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Bound Carbohydrates in Nature

Bound Carbohydrates in Nature

$59.99 (P)

Part of Lezioni Lincee

  • Author: Leonard Warren, The Wistar Institute of Anatomy and Biology, Philadelphia
  • Date Published: April 1994
  • availability: Available
  • format: Paperback
  • isbn: 9780521447430

$ 59.99 (P)

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About the Authors
  • Bound carbohydrates are an important and fascinating topic in biochemical and cancer research. Based on a series of invited lectures, this book focuses on the special role that bound carbohydrates play in nature and reflect the author's distinguished career in biochemical research. Some other topics covered are the properties of membrane glycoproteins, involved in the resistance of cells to drugs, and the metabolism of sugars and sialic acids, both of which form a pivotal role in the author's studies. The book chronicles just some of the huge advances that have been made in biochemistry over the past few decades.

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    Product details

    • Date Published: April 1994
    • format: Paperback
    • isbn: 9780521447430
    • length: 128 pages
    • dimensions: 216 x 140 x 8 mm
    • weight: 0.17kg
    • contains: 30 b/w illus. 7 tables
    • availability: Available
  • Table of Contents

    1. Introduction, history, microheterogeneity of bound carbohydrates
    function of bound carbohydrates
    inducible changes in bound carbohydrates
    programmed changes in bound carbohydrates
    a possible role for bound carbohydrates
    2. Sialic acids
    distribution of sialic acids in nature
    the metabolism of hexamines and sialic acids
    metabolic control of hexosamines and sialic acids
    asparagine N-glycosylation
    processing of lysomal enzymes
    biosynthesis of O-linked oligosaccarides
    modification of sialic acids
    genetic metabolic disorders involving sialic acids, glycosidases, bound carbohydrates in malignancy
    3. Multidrug resistance, properties of P-glycoprotein
    lysomes and multidrug resistance
    kinetics of influx and efflux of drugs, modulation of multidrug resistance
    the role of lipids in the accumulation of drugs by MDR cells
    P-170 and membrane lipids

  • Author

    Leonard Warren, The Wistar Institute of Anatomy and Biology, Philadelphia

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