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Look Inside Essential Evidence-based Medicine

Essential Evidence-based Medicine
with CD-ROM

2nd Edition


  • Author: Dan Mayer, Albany Medical College, New York
Sandi Pirozzo, Elizabeth Irish, John E. Kaplan, Laura J. Zakowski, Shobhina G. Chheda, Christing S. Seibert, Steven R. Simon
View all contributors
  • Date Published: November 2009
  • availability: In stock
  • format: Mixed media product
  • isbn: 9780521712415

£ 41.99
Mixed media product

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About the Authors
  • Essential Evidence-Based Medicine teaches the principles of research study methodology and design so that the reader can become better at critically analysing scientific and clinical studies. It describes the basic elements needed to understand biostatistics and epidemiology as applied to health care studies, and how to become a more discriminating reader of the medical literature by adopting the skills of critical appraisal. This new edition is extensively edited and updated, and includes two entirely new chapters on critical appraisal of qualitative research and communicating risks and evidence to patients. The text is geared towards the new learner, and assumes little clinical experience, starting with the basic principles of critical appraisal. A CD-ROM accompanies the book to enable students to test their learning through a series of questions, with answers provided. This is an ideal introductory text for medical students, health sciences students and a wide range of other healthcare professionals.

    • Easy to follow layout for students and teachers with examples of study designs and research issues
    • Includes new chapters on critical appraisal of qualitative research and communicating risks and evidence to patients
    • Accompanying CD-ROM for readers to test their learning through multiple choice and short answer questions
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    Reviews & endorsements

    'This is the best book on evidence-based medicine and the foundations for the evidence that I have ever come across. It is very easy to read, and each chapter can be read as a standalone explanation of a particular concept. I highly recommend this for the personal libraries of students, residents and attending physicians.' Doody's Book Reviews

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    Product details

    • Edition: 2nd Edition
    • Date Published: November 2009
    • format: Mixed media product
    • isbn: 9780521712415
    • length: 445 pages
    • dimensions: 247 x 192 x 29 mm
    • weight: 1.3kg
    • contains: 45 tables
    • availability: In stock
  • Table of Contents

    1. A brief history of medicine and statistics
    2. What is evidence-based medicine?
    3. Causation
    4. The medical literature: an overview
    5. Searching the medical literature Sandi Pirozzo and Elizabeth Irish
    6. Study design and strength of evidence
    7. Instruments and measurements: precision and validity
    8. Sources of bias
    9. Review of basic statistics
    10. Hypothesis testing
    11. Type I errors and number needed to treat
    12. Negative studies and Type II errors
    13. Risk assessment
    14. Multivariate analysis
    15. Randomized clinical trials (RCTs)
    16. Scientific integrity and the responsible conduct of research John E. Kaplan
    17. Applicability and strength of evidence
    18. Communicating evidence to patients Laura J. Zakowski, Shobhina G. Chheda and Christing S. Seibert
    19. Critical appraisal of qualitative research studies Steven R. Simon
    20. An overview of decision making in medicine
    21. Sources of error in the clinical encounter
    22. The use of diagnostic tests
    23. Utility and characteristics of diagnostic tests: likelihood ratios, sensitivity and specificity
    24. Bayes' theorem, predictive values, post-test probabilities, and interval likelihood ratios
    25. Comparing tests and using ROC curves
    26. Incremental gain and the threshold approach to diagnostic testing
    27. Sources of bias and critical appraisal of studies of diagnostic tests
    28. Screening tests
    29. Practice guidelines and clinical prediction rules
    30. Decision analysis and quantifying patient values
    31. Cost-effectiveness analysis
    32. Outcome analysis
    33. Meta-analysis and systematic reviews
    Appendix 1. Levels of evidence and grades of recommendations
    Appendix 2. Overview of critical appraisal
    Appendix 3. Formulas
    Appendix 4. Commonly used statistical tests
    Appendix 5. Proof of Bayes' theorem
    Appendix 6. Using balance sheets to calculate thresholds

  • Author

    Dan Mayer, Albany Medical College, New York
    Dan Mayer is Professor of Emergency Medicine, Albany Medical College, New York, USA.


    Sandi Pirozzo, Elizabeth Irish, John E. Kaplan, Laura J. Zakowski, Shobhina G. Chheda, Christing S. Seibert, Steven R. Simon

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