This chapter introduces social scientific perspectives and methods applicable to observing the relationship between artificial intelligence (AI) and religion. It discusses the contributions that anthropological and sociological approaches can make to this entanglement of two modern social phenomena while also drawing attention to the inherent biases and perspectives that both fields bring with them due to their histories. Examples of research on religion and AI are highlighted, especially when they demonstrate agile and new methodologies for engaging with AI in its many applications; including but not limited to online worlds, multimedia formats, games, social media and the new spaces made by technological innovation such as the innovations such as the platforms underpinning the gig economy. All these AI-enabled spaces can be entangled with religious and spiritual conceptions of the world. This chapter also aims to expand upon the relationship between AI and religion as it is perceived as a general concept or object within human society and civilisation. It explains how both anthropology and sociology can provide frameworks for conceptualising that relationship and give us ways to account for our narratives of secularisation – informed by AI development – that see religion as a remnant of a prior, less rational stage of human civilisation.