Published online by Cambridge University Press: 12 February 2021
Despite the various advances and increasing success rates of assisted conception treatment in recent years, implantation continues to be a rate limiting step (). The first successful IVF treatment performed by the pioneers Patrick Steptoe and Robert Edwards which led to the birth of Louise Joy Brown in 1978, was achieved in a fresh embryo transfer cycle. The subsequent implementation of cryopreservation techniques in the IVF laboratory facilitated the cryopreservation and storage of supernumerary embryos which were not chosen for a fresh transfer. Laboratory techniques have improved significantly over the years and due to the improved survival rates of cryopreserved oocytes, cleavage and blastocyst-stage embryos, cryopreservation of gametes and embryos has become part of everyday routine clinical practice ().
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