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Chapter 3 - Neuroanatomical Findings in Bipolar Disorder

from Section 2 - Anatomical Studies

Published online by Cambridge University Press:  12 January 2021

By
Giulia Tronchin  and
Colm McDonald
Edited by
Sudhakar Selvaraj ,
Paolo Brambilla  and
Jair C. Soares
Sudhakar Selvaraj
Affiliation:
UTHealth School of Medicine, USA
Paolo Brambilla
Affiliation:
Università degli Studi di Milano
Jair C. Soares
Affiliation:
UT Harris County Psychiatric Center, USA
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Summary

Over the past three decades, numerous cross-sectional neuroimaging studies have reported neuroanatomical abnormalities in patients with bipolar disorder compared with healthy volunteers. These studies have highlighted those anatomical regions likely to harbor pathophysiological abnormalities underpinning the disorder. However, there are inconsistencies in several of the findings reported, and the precise etiology of structural brain abnormalities remains unclear – for example, the extent to which neuroanatomical abnormalities are driving illness development as distinct from consequential to its treatment.

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Chapter
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Mood Disorders
Brain Imaging and Therapeutic Implications
 , pp. 16 - 27
Publisher: Cambridge University Press
Print publication year: 2021

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