References
Allfrey, V. G., Faulkner, R., and Mirsky, A. E. (1964). Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis. Proceedings of the National Academy of Sciences USA, 51, 786–794.
Allis, C. D., Jenuwein, T., Reinberg, D., and Caparros, M. L. (2007). Epigenetics. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
Appasani, K. (2007). Epigenomics and sequencing: an intertwined and emerging big science of the next decade. Pharmacogenomics, 8, 1109–1113.
Barr, M. L. and Bertram, E. G. (1949). A morphological distinction between neurons of the male and female, and the behaviour of the nucleolar satellite during accelerated nucleoprotein synthesis. Nature, 163, 676–677.
Bernstein, B. E., Stamatoyannopoulos, J. A., Costello, J. F., et al. (2010). The NIH Roadmap epigenomics mapping consortium. Nature Biotechnology, 28, 1045–1048.
Bird, A. (2007). Perceptions of epigenetics. Nature, 447, 396–398.
Brownell, J. E. and Allis, C. D. (1995). An activity gel assay detects a single, catalytically active histone acetyltransferase subunit in Tetrahymena macronuclei. Proceedings of the National Academy of Sciences USA, 92, 6364–6368.
Callinan, P. A. and Feinberg, A. P. (2006). The emerging science of epigenomics. Human Molecular Genetics, 15, R95–R101.
Cloud, J. (2010). Why your DNA isn’t your destiny. Time Magazine, January 06.
Cyranoski, D. (2009). Two by two. Nature, 458, 826–829.
ENCODE Project Consortium (
2007).
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.
Nature,
447,
799–816.
Esteller, M. (2008). Epigenetics in evolution and disease. Lancet, 372, S90–S96.
Esteller, M. (2009). Epigenetics in Biology and Medicine. Boca Raton, FL: CRC Press.
Feinberg, A. P. (2010). Epigenomics reveals a functional genome anatomy and a new approach to common disease. Nature Biotechnology, 28, 1049–1052.
Feinberg, A. P. and Vogelstein, B. (1983). Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature, 301, 89–92.
Ferguson-Smith, A. C., Greally, J. M., and Martienssen, R. A. (2009). Epigenomics. New York: Springer.
Flemming, W. (1879). Beitrage zur Kenntniss der Zelle und ihrer Lebenserscheinungen. Archives für mikroskopische Anatomie, 16, 302–436.
Holliday, R. and Pugh, J. E. (1975). DNA modification mechanisms and gene activity during development. Science, 187, 226–232.
Jablonka, E. and Lamb, M. (1995). Epigenetic Inheritance and Evolution: The Lamarckian Dimension. New York: Oxford University Press.
Kouzarides, T. (2007). Chromatin modifications and their function. Cell, 128, 693–705.
Lyon, M. (1961). Gene action in the X-chromosome of the mouse (Mus musculus L). Nature, 190, 372–373.
Petronis, A. (2010). Epigenetics as a unifying principle in the aetiology of complex traits and diseases. Nature, 465, 721–727.
Plath, K., Fang, J., Mlynarczyk-Evans, S. K., et al. (2003). Role of histone H3 lysine 27 methylation in X inactivation. Science, 300, 131–135.
Richards, E. J. (
2006).
Opinion: Inherited epigenetic variation – revisiting soft inheritance.
Nature Reviews Genetics,
7,
395–401.
Riggs, A. D. (
1975).
X-inactivation, differentiation and DNA methylation.
Cytogenetics and Cell Genetics,
14,
9–25.
Ronaghi, M., Uhlen, M., and Nyren, P. (1998). A sequencing method based on real-time pyrophosphate detection. Science, 281, 363–365.
Satterlee, J. S., Schubeler, D., and Ng, H. H. (2010). Tackling the epigenome: challenges and opportunities for collaboration. Nature Biotechnology, 28, 1039–1044.
Schones, D. E., Cui, K., Cuddapah, S., et al. (2008). Dynamic regulation of nucleosome positioning in the human genome. Cell, 132, 887–898.
Tost, J. (2010). DNA Methylation: Methods and Protocols. New York: Springer.
Waddington, C. H. (
1939).
Introduction to Modern Genetics.
London:
Macmillan.
Waddington, C. H. (
1942).
The epigenotype.
Endeavour,
1,
18–20.
