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Gabapentin

Published online by Cambridge University Press:  01 June 2018

Philip N. Patsalos
Affiliation:
UCL Institute for Neurology
Erik K. St Louis
Affiliation:
Mayo Clinic
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Publisher: Cambridge University Press
Print publication year: 2018

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Bergey, GK, Morris, HH, Rosenfeld, W, Blume, WT, Penovich, PE, Morrell, MJ, Leiderman, DB, Crockatt, JG, LaMoreaux, L, Garofalo, E, Pierce, M. Gabapentin monotherapy: I. An 8-day, double-blind, dose-controlled, multicenter study in hospitalized patients with refractory complex partial or secondarily generalized seizures. The US Gabapentin Study Group 88/89. Neurology 1997; 49: 739745.CrossRefGoogle ScholarPubMed
Costa, J, Fareleira, F, Ascenção, R, Borges, M, Sampaio, C, Vaz-Carneiro, A. Clinical comparability of the new antiepileptic drugs in refractory partial epilepsy: a systematic review and meta-analysis. Epilepsia 2011; 52: 12801291.CrossRefGoogle ScholarPubMed
Fink, K, Dooley, DJ, Meder, WP, Suman-Chauhan, N, Duffy, S, Clusmann, H, Gothert, M. Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex. Neuropharmacology 2002; 42: 229236.CrossRefGoogle ScholarPubMed
French, J, Glue, P, Friedman, D, Almas, M, Yardi, N, Knapp, L, Pitman, V, Posner, HB. Adjunctive pregabalin vs gabapentin for focal seizures: interpretation of comparative outcomes. Neurology 2016; 87: 12421249.CrossRefGoogle ScholarPubMed
French, JA, Kanner, AM, Bautista, J, et al. Efficacy and tolerability of the new antiepileptic drugs I: treatment of new onset epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology 2004; 62: 12521260.CrossRefGoogle Scholar
French, JA, Kanner, AM, Bautista, J, et al. Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy: efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology 2004; 62: 12611273.CrossRefGoogle Scholar
Fujii, H, Goel, A, Bernard, N, Pistelli, A, Yates, LM, Stephens, S, Han, JY, Matsui, D, Etwell, F, Einarson, TR, Koren, G, Einarson, A. Pregnancy outcomes following gabapentin use: results of a prospective comparative cohort study. Neurology 2013; 80: 15651570.CrossRefGoogle ScholarPubMed
Gidal, BE, Radulovic, LL, Kruger, S, Rutecki, P, Pitterle, M, Bockbrader, HN. Inter- and intra-subject variability in gabapentin absorption and absolute bioavailability. Epilepsy Research 2000; 40: 123127.Google Scholar
Johannessen Landmark, C, Patsalos, PN. Drug interactions involving the new second- and third-generation antiepileptic drugs. Expert Reviews in Neurotherapeutics 2010; 10: 119140.CrossRefGoogle ScholarPubMed
Marson, AG, Kadir, ZA, Hutton, JL, Chadwick, DW. The new antiepileptic drugs: a systematic review of their efficacy and tolerability. Epilepsia 1997; 38: 859880.Google Scholar
McLean, MJ, Gidal, BE. Gabapentin dosing in the treatment of epilepsy. Clinical Therapeutics 2003; 25: 13821406.CrossRefGoogle ScholarPubMed
Ohman, I, Vitolis, S, Tomson, T. Pharmacokinetics of gabapentin during delivery, in the neonatal period and lactation. Epilepsia 2005; 46: 16211624.CrossRefGoogle ScholarPubMed
Patsalos, PN. Antiepileptic drug interactions: a clinical guide, 3rd edition. Springer, London, UK; 2016.CrossRefGoogle Scholar
Patsalos, PN, Zugman, M, Lake, C, James, A, Ratnaraj, N, Sander, JW. Serum protein binding of 25 antiepileptic drugs in a routine clinical setting: a comparison of free non-protein-bound concentrations. Epilepsia 2017; 58: 12341243.CrossRefGoogle Scholar
St. Louis, EK. The art of managing conversions between antiepileptic drugs; maximizing patient tolerability and quality of life. Pharmaceuticals 2010; 3: 29562969.Google Scholar
St. Louis, EK, Gidal, BE, Henry, TR, Kaydanova, Y, Krumholz, A, McCabe, PH, Montouris, GD, Rosenfeld, WE, Smith, BJ, Stern, JM, Waterhouse, EJ, Schulz, RM, Garnett, WR, Bramley, T. Conversions between monotherapies in epilepsy: expert consensus. Epilepsy and Behavior 2007; 11: 222234.CrossRefGoogle ScholarPubMed
Vollmer, KO, von Hodenberg, A, Kolle, EU. Pharmacokinetics and metabolism of gabapentin in rat, dog and man. Arzneimittel Forschung Drug Research 1988; 36: 830839.Google Scholar
Wolf, SM, Shinner, S, Kang, H, Gil, KB, Moshe, SL. Gabapentin toxicity in children manifesting as behavioural changes. Epilepsia 1995; 36: 12031205.Google Scholar

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