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12 - The baby with an abnormal antenatal scan: congenital malformations

from Section III - Solving clinical problems and interpretation of test results

Published online by Cambridge University Press:  07 December 2009

By
Cornelia F. Hagmann ,
Janet M. Rennie  and
Nicola J. Robertson
Edited by
Janet M. Rennie ,
Cornelia F. Hagmann  and
Nicola J. Robertson
Cornelia F. Hagmann
Affiliation:
Clinical Lecturer and Honorary Consultant Neonatologist, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London Hospitals
Janet M. Rennie
Affiliation:
Consultant and Senior Lecturer in Neonatal Medicine, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London Hospitals
Nicola J. Robertson
Affiliation:
Senior Lecturer in Neonatology and Honorary Consultant Neonatologist, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London Hospitals
Janet M. Rennie
Affiliation:
University College London
Cornelia F. Hagmann
Affiliation:
University College London
Nicola J. Robertson
Affiliation:
University College London
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Summary

Introduction – clinical presentation

Increasingly, neonatologists are asked to advise women whose fetus is thought to have a congenital malformation of the brain or spinal cord because of abnormal antenatal ultrasound imaging. Counseling women and their partners in this situation is delicate and important work, but can be very difficult given the current state of knowledge about the natural history of antenatally diagnosed abnormalities and the imprecision of diagnosis. Antenatal magnetic resonance imaging (MRI) can assist, but this technique should not be used solely “for reassurance” – in our experience this can generate more problems than it solves. Our aim in this chapter is not only to provide examples of images including some rare conditions, but also to give guidance regarding further investigation and prognosis to help neonatologists who are faced with the management of a fetus and baby with a suspected cerebral malformation.

The commonest problems presenting to the neonatologist are agenesis of the corpus callosum, ventriculomegaly, and cystic lesions (arachnoid cysts, suspected Dandy Walker cysts or persisting choroid plexus cysts). Postnatally the findings of subependymal cysts and striate vasculopathy are also common. Midline lesions of the skin over the spinal cord are not rare. As a result we make no excuse for concentrating on these conditions, but we have chosen to present the material in a systematic way.

Disorders of prosencephalic development

The spectrum of pathology varies from profound derangement (aprosencephaly) to disturbances of the midline prosencephalic development (agenesis of the corpus callosum).

Type
Chapter
Information
Neonatal Cerebral Investigation , pp. 248 - 268
Publisher: Cambridge University Press
Print publication year: 2008

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  • The baby with an abnormal antenatal scan: congenital malformations
    • By Cornelia F. Hagmann, Clinical Lecturer and Honorary Consultant Neonatologist, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London Hospitals, Janet M. Rennie, Consultant and Senior Lecturer in Neonatal Medicine, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London Hospitals, Nicola J. Robertson, Senior Lecturer in Neonatology and Honorary Consultant Neonatologist, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London Hospitals
  • Edited by Janet M. Rennie, University College London, Cornelia F. Hagmann, University College London, Nicola J. Robertson, University College London
  • Book: Neonatal Cerebral Investigation
  • Online publication: 07 December 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511544750.014
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  • The baby with an abnormal antenatal scan: congenital malformations
    • By Cornelia F. Hagmann, Clinical Lecturer and Honorary Consultant Neonatologist, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London Hospitals, Janet M. Rennie, Consultant and Senior Lecturer in Neonatal Medicine, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London Hospitals, Nicola J. Robertson, Senior Lecturer in Neonatology and Honorary Consultant Neonatologist, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London Hospitals
  • Edited by Janet M. Rennie, University College London, Cornelia F. Hagmann, University College London, Nicola J. Robertson, University College London
  • Book: Neonatal Cerebral Investigation
  • Online publication: 07 December 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511544750.014
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • The baby with an abnormal antenatal scan: congenital malformations
    • By Cornelia F. Hagmann, Clinical Lecturer and Honorary Consultant Neonatologist, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London Hospitals, Janet M. Rennie, Consultant and Senior Lecturer in Neonatal Medicine, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London Hospitals, Nicola J. Robertson, Senior Lecturer in Neonatology and Honorary Consultant Neonatologist, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London Hospitals
  • Edited by Janet M. Rennie, University College London, Cornelia F. Hagmann, University College London, Nicola J. Robertson, University College London
  • Book: Neonatal Cerebral Investigation
  • Online publication: 07 December 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511544750.014
Available formats
×