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Chapter 9 - Dermatological Complications in Transplant Patients and Composite Tissue Allotransplant Pathology

Published online by Cambridge University Press:  17 March 2018

Phillip Ruiz
Affiliation:
University of Miami School of Medicine
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Publisher: Cambridge University Press
Print publication year: 2018

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References

Kuijken, I, B. 2000. Skin Cancer Risk Associated with Immunosuppressive Therapy in Organ Transplant Recipients: Epidemiology and Proposed Mechanisms. BioDrugs, 14(5): 319–29.Google Scholar
Ulrich, C, Hackethal, M, Meyer, T, Geusau, A, Nindl, I, Ulrich, M, Forschner, T, Sterry, W, Stockfleth, E. 2008. Skin Infections in Organ Transplant Recipients. JDDG, 6: 98104.Google Scholar
Belloni-Fortina, A, Piaserico, S, Bordignon, M, Gambato, M, Senzolo, M, Russo, FP, Peserico, A, De Matteis, G, Perissinotto, E, Cillo, U, Vitale, A, Alaibac, M, Burra, P. Skin Cancer and Other Cutaneous Disorders in Liver Transplant Recipients. Acta Derm Venereol, 2012 Jul;92(4): 411–5.Google Scholar
Mays, SR, K.J., Truong, E, Kontoyiannis, DPHymes, SR. 2007. Approach to the Morbilliform Eruption in the Hematopoietic Transplant Patient. Seminars in Cutaneous Medicine and Surgery, 26: 155162.Google Scholar
Kohler, S, H.M., Chao, NJ, Smoller, BR. 1997. Value of Skin Biopsies in Assessing Prognosis and Progression of Acute Graft-versus-Host Disease. Am J Surg Pathol, 21: 988996.CrossRefGoogle ScholarPubMed
Baack, BR, B.W. 1991. Chemotherapy-induced Acral Erythema. Journal of American Academy of Dermatology, 24: 457–61.Google Scholar
Bauer, DJ, H.A., Horn, TD. 1993. Histologic Comparison of Autologous Graft-vs-Host Reaction and Cutaneous Eruption of Lymphocyte Recovery. Archives of Dermatology, 129: 855–8.Google Scholar
Sandoval, M, Ortiz, M, Díaz, C, Majerson, D, Molgó, M. Cutaneous Manifestations in Renal Transplant Recipients of Santiago, Chile. Transplant Proc, 2009 Nov;41(9): 3752–4.Google Scholar
Radwan-Oczko, M, Boratynska, M, Klinger, M, Zietek, M. Risk Factors of Gingival Overgrowth in Kidney Transplant Recipients Treated with Cyclosporine A. Ann Transplant, 2003;8(4): 5762.Google Scholar
Güleç, AT, Haberal, M. Lip and Oral Mucosal Lesions in 100 Renal Transplant Recipients. J Am Acad Dermatol, 2010 Jan;62(1): 96101.Google Scholar
Aboujaoude, W, M.M., Govani, MV. 2004. Lymphedema Associated with Sirolimus in Renal Transplant Recipients. Transplantation, 77(7): 1094–6.Google Scholar
Mahé, E, M.E., Lechaton, S, Sang, KH, Mansouri, R, Ducasse, MF, Mamzer-Bruneel, MF, de Prost, Y, Kreis, H, Bodemer, C. 2005. Cutaneous Adverse Events in Renal Transplant Recipients Receiving Sirolimus-based Therapy. Transplantation, 79(4): 476–82.Google Scholar
Mohaupt, MG, V.B., Frey, FJ. 2001. Sirolimus-associated Eyelid Edema in Kidney Transplant Recipients. Transplantation, 72(1): 162–4.Google Scholar
van Gelder, T, T.M.C., Hené, R, Weimar, W, Hoitsma, A. 2003. Oral Ulcers in Kidney Transplant Recipients Treated with Sirolimus and Mycophenolate Mofetil. Transplantation, 75(6): 788–91.Google Scholar
Mahé, E, M.E., Lechaton, S, Drappier, JC, de Prost, Y, Kreis, H, Bodemer, C. 2006. Acne in Recipients of Renal Transplantation Treated with Sirolimus: Clinical, Microbiologic, Histologic, Therapeutic, and Pathogenic Aspects. Journal of American Academy of Dermatology, 55(1): 139–42.Google Scholar
Lehmkuhl, H, R.H., Eisen, H, Valantine, H. 2005. Everolimus (Certican) in Heart Transplantation: Optimizing Renal Function through Minimizing Cyclosporine Exposure. Transplantation Proceedings, 37(10): 4145–9.Google Scholar
Cowper, SE, S.L., Bhawan, J, Robin, HS, LeBoit, PE. 2001. Nephrogenic Fibrosing Dermopathy. American Journal of Dermatopathology, 23(5): 383–93.Google Scholar
Girardi, M, Kay, J, Elston, DM, Leboit, PE, Abu-Alfa, A, Cowper, SE. Nephrogenic Systemic Fibrosis: Clinicopathological Definition and Workup Recommendations. J Am Acad Dermatol, 2011 Dec;65(6): 1095–106.Google Scholar
Levine, JM, T.R., Elman, LB, Bird, SJ, Lavi, E, Stolzenberg, ED, McGarvey, ML, Asbury, AK, Jimenez, SA. 2004. Involvement of Skeletal Muscle in Dialysis-associated Systemic Fibrosis (Nephrogenic Fibrosing Dermopathy). Muscle Nerve, 30(5): 569–77.Google Scholar
Filipovich, AH, Weisdorf, D, Pavletic, S, Socie, G, Wingard, JR, Lee, SJ, Martin, P, Chien, J, Przepiorka, D, Couriel, D, Cowen, EW, Dinndorf, P, Farrell, A, Hartzman, R, Henslee-Downey, J, Jacobsohn, D, McDonald, G, Mittleman, B, Rizzo, JD, Robinson, M, Schubert, M, Schultz, K, Shulman, H, Turner, M, Vogelsang, G, Flowers, ME. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: I. Diagnosis and Staging Working Group Report. Biol Blood Marrow Transplant, 2005 Dec;11(12): 945–56Google Scholar
Aractingi, S, C.O. 1998. Cutaneous Graft-versus-Host Disease. Archives of Dermatology, 134(5): 602–12.Google Scholar
Johnson, ML, F.E. 1998. Graft-versus-Host Reactions in Dermatology. Journal of American Academy of Dermatology, 38(3): 369–92.Google Scholar
Lerner, KG, Kao, GF, Storb, R, Buckner, CD, Clift, RA, Thomas, ED. Histopathology of Graft-vs-Host Reaction (GvHR) in Human Recipients of Marrow from HL-A Matched Sibling Donors. Transplant Proc, 1974 Dec;6(4): 367–71.Google Scholar
Horn, TD. Acute Cutaneous Eruptions after Marrow Ablation: Roses by Other Names? J Cutan Pathol, 1994 Oct;21(5): 385–92.Google Scholar
Häusermann, P, Walter, RB, Halter, J, Biedermann, BC, Tichelli, A, Itin, P, Gratwohl, A. Cutaneous Graft-versus-Host Disease: A Guide for the Dermatologist. Dermatology, 2008;216(4): 287304.CrossRefGoogle ScholarPubMed
Tsoi, MS, S.R., Jones, E, Weiden, PL, Shulman, H, Witherspoon, R, Atkinson, K, Thomas, ED. 1978. Deposition of IgM and Complement at the Dermoepidermal Junction in Acute and Chronic Cutaneous Graft-vs-Host Disease in Man. Journal of Immunology, 120(5): 1485–92.Google Scholar
Gilliam, A, W.-M.D., Korngold, R, Murphy, G. 1996. Apoptosis is the Predominant Form of Epithelial Target Cell Injury in Acute Experimental Graft versus Host Disease. Journal of Investigative Dermatology, 107: 377383.Google Scholar
Leskinen, R, T.E., Volin, L, Ruutu, T, Häyry, P. 1992. Immunohistology of Skin and Rectum Biopsies in Bone Marrow Transplant Recipients. APMIS, 100: 1115–22.CrossRefGoogle ScholarPubMed
Drijkoningen, M, D.W.-P.C., Tricot, G, Degreef, H, Desmet, V. 1988. Drug-induced Skin Reactions and Cutaneous Graft-versus-Host Reaction: A Comparative Immunohistochemical Study. Blut, 56: 6973.Google Scholar
Sale, GE, L.K., Barker, EA, Shulman, HM, Thomas, ED. 1977. The Skin Biopsy in the Diagnosis of Acute Graft-versus-Host Disease in Man. American Journal of Pathology, 89(3): 621–35.Google Scholar
Zhou, Y, B.M., Rivers, JK. 2000. Clinical Significance of Skin Biopsies in the Diagnosis and Management of Graft-vs-Host Disease in Early Postallogeneic Bone Marrow Transplantation. Archives of Dermatology, 136(6): 717–21.Google Scholar
Paczesny, S, Braun, TM, Levine, JE, Hogan, J, Crawford, J, Coffing, B, Olsen, S, Choi, SW, Wang, H, Faca, V, Pitteri, S, Zhang, Q, Chin, A, Kitko, C, Mineishi, S, Yanik, G, Peres, E, Hanauer, D, Wang, Y, Reddy, P, Hanash, S, Ferrara, JL. Elafin is a Biomarker of Graft-versus-Host Disease of the Skin. Sci Transl Med, 2010 Jan 6;2(13): 13ra2.Google Scholar
Atkinson, K. 1990. Chronic Graft-versus-Host Disease. Bone Marrow Transplant, 5(2):6982.Google Scholar
Rouquette-Gally, AM, B.D., Gluckman, E, Abuaf, N, Combrisson, A. 1987. Autoimmunity in 28 Patients after Allogeneic Bone Marrow Transplantation: Comparison with Sjögren Syndrome and Scleroderma. British Journal of Haematology, 66(1): 45–7.Google Scholar
Leber, B, W.I., Rodriguez, A, McBride, JA, Carter, R, Brain, MC. 1993. Reinduction of Remission of Chronic Myeloid Leukemia by Donor Leukocyte Transfusion Following Relapse after Bone Marrow Transplantation: Recovery Complicated by Initial Pancytopenia and Late Dermatomyositis. Bone Marrow Transplantation, 12(4): 405–7.Google Scholar
Ollivier, I, W.P., Gherardi, R, Wechsler, J, Kuentz, M, Cosnes, A, Revuz, J, Bagot, M. 1998. Dermatomyositis-like Graft-versus-Host Disease. British Journal of Dermatology, 138(3): 558–9.CrossRefGoogle ScholarPubMed
Creamer, D, M.-S.C., Osborne, G, Kenyon, M, Salisbury, JR, Devereux, S, Pagliuca, A, Ho, AY, Mufti, GJ, du Vivier, AW. 2007. Eczematoid Graft-vs-Host Disease: A Novel Form of Chronic Cutaneous Graft-vs-Host Disease and Its Response to Psoralen UV-A Therapy. Archives of Dermatology, 143(9): 1157–62.Google Scholar
Sloane, JP, T.J., Imrie, SF, Easton, DF, Powles, RL. 1984. Morphological and Immunohistological Changes in the Skin in Allogeneic Bone Marrow Recipients. Journal of Clinical Pathology, 37(8): 919–30.Google Scholar
Tanasescu, S, B.X., Thomine, E, Boullie, MC, Vannier, JP, Tron, P, Joly, P, Lauret, P. 1999. Eczema-like Cutaneous Graft versus Host Disease Treated by UV-B Therapy in a 2-Year-Old Child. Annals of Dermatology and Venereology, 126(1): 51–3.Google Scholar
Andrews, ML, R.I., Weedon, D. 1997. Cutaneous Manifestations of Chronic Graft-versus-Host Disease. Australasian Journal of Dermatology, 38(2): 5362.Google Scholar
Farmer, E. 1985. Human Cutaneous Graft-versus-Host Disease. Journal of Investigative Dermatology, 85(1, suppl): 124S–8S.Google Scholar
White, JM, C.D., du Vivier, AW, Pagliuca, A, Ho, AY, Devereux, S, Salisbury, JR, Mufti, GJ. 2007. Sclerodermatous Graft-versus-Host Disease: Clinical Spectrum and Therapeutic Challenges. British Journal of Dermatology, 156(5): 1032–8.Google Scholar
Beers, B, K.R., Kaye, V, Dahl, M. 1993. Unilateral Linear Lichenoid Eruption after Bone Marrow Transplantation: An Unmasking of Tolerance to an Abnormal Keratinocyte Clone? Journal of American Academy of Dermatology, 28: 888–92.Google Scholar
Peñas, PF, J.-C.M., Aragüés, M, Fernández-Herrera, J, Fraga, J, García-Díez, A. 2002. Sclerodermatous Graft-vs-Host Disease: Clinical and Pathological Study of 17 Patients. Archives of Dermatology, 138(7): 924–34.Google Scholar
Shulman, HM, Kleiner, D, Lee, SJ, Morton, T, Pavletic, SZ, Farmer, E, Moresi, JM, Greenson, J, Janin, A, Martin, PJ, McDonald, G, Flowers, ME, Turner, M, Atkinson, J, Lefkowitch, J, Washington, MK, Prieto, VG, Kim, SK, Argenyi, Z, Diwan, AH, Rashid, A, Hiatt, K, Couriel, D, Schultz, K, Hymes, S, Vogelsang, GB. Histopathologic Diagnosis of Chronic Graft-versus-Host Disease: National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: II. Pathology Working Group Report. Biol Blood Marrow Transplant. 2006 Jan;12(1):3147.Google Scholar
Roujeau, JC, R.J., Touraine, R. 1980. Graft versus Host Reactions. In: Rook, A, Savin, J, eds. Recent Advances in Dermatology, 5: 131–57.Google Scholar
Nakhleh, RE, Miller, W, Snover, DC. Significance of Mucosal vs Salivary Gland Changes in Lip Biopsies in the Diagnosis of Chronic Graft-vs-Host Disease. Arch Pathol Lab Med, 1989 Aug;113(8): 932–4.Google Scholar
Rubin, R. 1994. Clinical Approach to Infection in the Compromised Host, 3rd ed. Plenum Medical Book Company. New York, N.Y.Google Scholar
Gourishankar, S, M.J., Jhangri, GS, Preiksaitis, JK. 2004. Herpes Zoster Infection Following Solid Organ Transplantation: Incidence, Risk Factors and Outcomes in the Current Immunosuppressive Era. American Journal of Transplantation, 4(1): 108–15.Google Scholar
Smith, SR, B.D., Alexander, BD, Greenberg, A. 2001. Viral Infections after Renal Transplantation. American Journal of Kidney Diseases, 37: 659–76.Google Scholar
LaRocco, MT, B.S. 1997. Infection in the Bone Marrow Transplant Recipient and Role of the Microbiology Laboratory in Clinical Transplantation. Clinical Microbiology Reviews, 10(2):277–97.CrossRefGoogle Scholar
Appleton, AL, S.L., Peiris, JS, Taylor, CE, Wilkes, J, Green, MA, Pearson, AD, Kelly, PJ, Malcolm, AJ, Proctor, SJ, et al. 1995. Human Herpes Virus-6 Infection in Marrow Graft Recipients: Role in Pathogenesis of Graft-versus-Host Disease. Bone Marrow Transplantation, 16(6).Google Scholar
Bakir, M, B.J., Newell, KA, Millis, JM, Buell, JF, Arnow, PM. 2001 Epidemiology and Clinical Consequences of Vancomycin-resistant Ente-Rococci in Liver Transplant Patients. Transplantation, 72(6): 1032–7.CrossRefGoogle ScholarPubMed
Singh, N, P.D., Chang, FY Gayowski, T, Squier, C, Wagener, MM, Marino, IR. 2000. Methicillin-resistant Staphylococcus Aureus: The Other Emerging Resistant Gram-positive Coccus among Liver Transplant Recipients. Clinical Infectious Disease, 30(2): 322–7.Google Scholar
Schmied, E, D.J., Euvrard, S. 2004. Nontumoral Dermatologic Problems after Liver Transplantation. Liver Transplantation, 10(3): 331–9.CrossRefGoogle ScholarPubMed
Strauss, G, M.A., Rasmussen, A, Kirkegaard, P. 1997. Staphylococcal Scalded Skin Syndrome in a Liver Transplant Patient. Liver Transplantation Surgery, 3(4): 435–6.Google Scholar
Fishman, JA, R.R. 1998. Infection in Organ-transplant Recipients. New England Journal of Medicine, 338(24):1741–51.Google Scholar
Varon, NF, A.G. 2004 Emerging Trends in Infections among Renal Transplant Recipients. Expert Rev Anti Infect Ther, 2(1): 95109.Google Scholar
Nathan, DL, S.S. Kestenbaum, TM, Casparian, JM. 2000. Cutaneous Mycobacterium Chelonae in a Liver Transplant Patient. Journal of American Academy of Dermatology, 43: 333–6.Google Scholar
Patel, R, R.G. Keating, MR, Paya, CV. 1994. Infections Due to Nontuberculous Mycobacteria in Kidney, Heart, and Liver Transplant Recipients. Clinical Infectious Disease, 19: 263.Google Scholar
Paya, C. 1993. Fungal Infections in Solid-organ Transplantation. Clinical Infectious Disease, 16(5): 677–88.Google Scholar
Panackal, A, I.A., Hanley, EW, Marr, KA. 2006. Aspergillus Ustus Infections among Transplant Recipients. Emerging Infectious Diseases, 12(3): 403–8.Google Scholar
Stiller, MJ, T.L., Rosenthal, SA, Riordan, A, Potter, J, Shupack, JL, Gordon, MA. 1994. Primary Cutaneous Infection by Aspergillus Ustus in a 62-Year-Old Liver Transplant Recipient. Journal of American Academy of Dermatology, 31(2 Pt 2): 344–7.Google Scholar
Vagefi, PA, Cosimi, AB, Ginns, LC, Kotton, CN. 2008. Cutaneous Aspergillus Ustus in a Lung Transplant Recipient: Emergence of a New Opportunistic Fungal Pathogen. The Journal of Heart and Lung Transplantation, 27: 131134.Google Scholar
Husain, S, Wagener, MM, Singh, N. 2001. Cryptococcus Neoformans Infection in Organ Transplant Recipients: Variables Influencing Clinical Characteristics and Outcome. Emerging Infectious Diseases, 7: 375–81.Google Scholar
Virgili, A, Z.M., La Malfa, V, Strumia, R, Bedani, PL. 1999. Prevalence of Superficial Dermatomycoses in 73 Renal Transplant Recipients. Dermatology, 199(1): 31–4.Google Scholar
Greenlee, RT, Murray, T, Bolden, S, Wingo, PA. 2000. Cancer Statistics, 2000. CA: A Cancer Journal for Clinicians, 50: 733.Google ScholarPubMed
Ulrich, C, S.T., Nindl, I, Meyer, T, Sterry, W, Stockfleth, E. 2003 Cutaneous Precancers in Organ Transplant Recipients: An Old Enemy in a New Surrounding. Br J Dermatol, 149(Suppl 66): 40–2.Google Scholar
Berg, D, Otley, CC. 2002. Skin Cancer in Organ Transplant Recipients: Epidemiology, Pathogenesis, and Management. Journal of the American Academy of Dermatology, 47: 117; quiz 18–20.Google Scholar
Herman, S, Rogers, HD, Ratner, D. 2007. Immunosuppression and Squamous Cell Carcinoma: A Focus on Solid Organ Transplant Recipients. SKINmed, 6: 234–8.Google Scholar
Perrem, K, L.A., Conneely, M, Wahlberg, H, Murphy, G, Leader, M, Kay, E. 2007. The Higher Incidence of Squamous Cell Carcinoma in Renal Transplant Recipients Is Associated with Increased Telomere Lengths. Human Pathology, 38(2): 351–8.Google Scholar
Dang, C, Koehler, A, Forschner, T, Sehr, P, Michael, K, Pawlita, M, Stockfleth, E, Nindl, I. 2006. E6/E7 Expression of Human Papillomavirus Types in Cutaneous Squamous Cell Dysplasia and Carcinoma in Immunosuppressed Organ Transplant Recipients. British Journal of Dermatology, 155: 129–36.Google Scholar
Fuchs, A, Marmur, E. 2007. The Kinetics of Skin Cancer: Progression of Actinic Keratosis to Squamous Cell Carcinoma. Dermatologic Surgery, 33: 1099–101.Google Scholar
Euvard, S, Kanitakis, J, Claudy, A. 2003. Skin Cancers after Organ Transplantation. The New England Journal of Medicine, 348: 1681–91.Google Scholar
Boukamp, P. 2005. Non-melanoma Skin Cancer: What Drives Tumor Development and Progression? Carcinogenesis, 26(10): 1657–67.Google Scholar
Harwood, CA, P.C., McGregor, JM, Sheaff, MT, Leigh, IM, Cerio, R. 2006. Clinicopathologic Features of Skin Cancer in Organ Transplant Recipients: A Retrospective Case-control Series. Journal of American Academy of Dermatology, 54(2): 290300.Google Scholar
McGibbon, D. 1985. Malignant Epidermal Tumours. Journal of Cutaneous Pathology, 12(3–4): 224–38.Google Scholar
Penn, I. 1996. Malignant Melanoma in Organ Allograft Recipients. Transplantation, 61(2): 274–8.Google Scholar
Kubica, AW, Brewer, JD. 2012. Melanoma in Immunosuppressed Patients. Mayo Clinic Proceedings. Mayo Clinic, 87(10):9911003.Google Scholar
van Dijk, MC, A.K., van Hees, F, Klaasen, A, Blokx, WA, Kiemeney, LA, Ruiter, DJ. 2008. Expert Review Remains Important in the Histopathological Diagnosis of Cutaneous Melanocytic Lesions. Histopathology, 52(2): 139–46.Google Scholar
Neuburg, M. 2007. Transplant-associated Skin Cancer: Role of Reducing Immunosuppression. Journal of the National Comprehensive Cancer Network, 5: 541–9.Google Scholar
Sampio, MS, Cho, YW, Qazi, Y, Bunnapradist, S, Hutchinson, IV, Shah, T. 2012. Posttransplant Malignancies in Solid Organ Adult Recipients: An Analysis of the U.S. National Transplant Database. Transplantation, 94(10): 990–8.Google Scholar
Marcelin, AG, C.V., Dussaix, E. 2007. KSHV after an Organ Transplant: Should We Screen? Current Topics in Microbiology and Immunology, 312: 245–62.Google Scholar
Campistol, JM, Schena, FP. 2007. Kaposi’s Sarcoma in Renal Transplant Recipients–The Impact of Proliferation Signal Inhibitors. Nephrology Dialysis Transplantation, 22(Suppl 1): i1722.Google Scholar
Chow, JW, L.S. 1990. Endemic and Atypical Kaposi’s Sarcoma in Africa– Histopathological Aspects. Clinical and Experimental Dermatology, 15(4): 253–9.Google Scholar
Nagy, S, G.R., Kemeny, L, Szenohradszky, P, Dobozy, A. 2000. Iatrogenic Kaposi’s Sarcoma: HHV8 Positivity Persists but the Tumors Regress Almost Completely without Immunosuppressive Therapy. Transplantation, 69(10): 2230–1.Google Scholar
Gonthier, DM, Hartman, G, Holley, JL. 1992. Posttransplant Lymphoproliferative Disorder Presenting as an Isolated Skin Lesion. American Journal of Kidney Diseases, 19: 600–3.Google Scholar
Schumann, KW, Oriba, HA, Bergfeld, WF, Hsi, ED, Hollandsworth, K. 2000. Cutaneous Presentation of Posttransplant Lymphoproliferative Disorder. Journal of the American Academy of Dermatology, 42: 923–6.Google Scholar
Takahashi, S, Watanabe, D, Miura, K., Ozawa, H, Tamada, Y, Hara, K, Matsumoto, Y. 2007. Epstein-Barr Virus-associated Post-transplant Lymphoproliferative Disorder Presenting with Skin Involvement after CD34-selected Autologous Peripheral Blood Stem Cell Transplantation. European Journal of Dermatology, 17: 242–4.Google Scholar
Coyne, JD, Banerjee, SS, Bromley, M, Mills, S, Diss, TC, Harris, M. 2004. Post-transplant T-cell Lymphoproliferative Disorder/T-cell Lymphoma: A Report of Three Cases of T-anaplastic Large-cell Lymphoma with Cutaneous Presentation and a Review of the Literature. Histopathology, 44: 387–93.Google Scholar
Dreno, B, Mansat, E, Legoux, B, Litoux, P. 1998. Skin Cancers in Transplant Patients. Nephrol Dial Transplant, 13: 1374–9.Google Scholar
O’Connor, JP, Quinn, J, Wall, D, Petrie, JJ, Hardie, JR, Woodruff, PW. 1986. Cutaneous Angiosarcoma Following Graft Irradiation in a Renal Transplant Patient. Clinical Nephrology, 25: 54–5.Google Scholar
Kanitakis, J, Euvrard, S, Montazeri, A, Garnier, JL, Faure, M, Claudy, A. 1996. Atypical Fibroxanthoma in a Renal Graft Recipient. Journal of the American Academy of Dermatology, 35: 262–4.Google Scholar
Kolker, AR, Wolfort, FG, Upton, J, Tahan, SR, Hein, KD, Zewert, TE. 1998. Plantar Verrucous Carcinoma Following Transmetatarsal Amputation and Renal Transplantation. Annals of Plastic Surgery, 40: 515–9.Google Scholar
Lanzetta, M, Petruzzo, P, Dubernard, JM, Margreiter, R, Schuind, F, Breidenbach, W, Nolli, R, Schneeberger, S, van Holder, C, Gorantla, VS., et al. 2007. Second Report (1998–2006) of the International Registry of Hand and Composite Tissue Transplantation. Transplant Immunology, 18: 16.Google Scholar
Gabl, M, Pechlaner, S, Lutz, M, Bodner, G, Piza, H, Margreiter, R. 2004. Bilateral Hand Transplantation: Bone Healing under Immunosuppression with Tacrolimus, Mycophenolate Mofetil, and Prednisolone. Journal of Hand Surgery – American Volume, 29: 1020–7.Google Scholar
Levi, DM, Tzakis, AG, Kato, T, Madariaga, J, Mittal, NK, Nery, J, Nishida, S, Ruiz, P. 2003. Transplantation of the Abdominal Wall. Lancet, 361: 2173–6.Google Scholar
Devauchelle, B, Badet, L, Lengele, B, Morelon, E, Testelin, S, Michallet, M, D’Hauthuille, C, Dubernard, JM. 2006. First Human Face Allograft: Early Report. Lancet, 368: 203–9.Google Scholar
Kanitakis, J, Petruzzo, P, Jullien, D, Badet, L, Dezza, MC, Claudy, A, Lanzetta, M, Hakim, N, Owen, E, Dubernard, JM. 2005. Pathological Score for the Evaluation of Allograft Rejection in Human Hand (Composite Tissue) Allotransplantation. European Journal of Dermatology, 15: 235–8.Google Scholar
Cendales, LC, Kirk, AD, Moresi, JM, Ruiz, P, Kleiner, DE. 2006. Composite Tissue Allotransplantation: Classification of Clinical Acute Skin Rejection. Transplantation, 81: 418–22.Google Scholar
Bejarano, PA, Levi, D, Nassiri, M, Vincek, V, Garcia, M, Weppler, D, Selvaggi, G, Kato, T, Tzakis, A. 2004. The Pathology of Full-thickness Cadaver Skin Transplant for Large Abdominal Defects: A Proposed Grading System for Skin Allograft Acute Rejection. American Journal of Surgical Pathology, 28: 670–5.CrossRefGoogle ScholarPubMed
Cendales, LC, K.J., Schneeberger, S, Burns, C, Ruiz, P, Landin, L, Remmelink, M, Hewitt, CW, Landgren, T, Lyons, B, Drachenberg, CB, Solez, K, Kirk, AD, Kleiner, DE, Racusen, L. 2008. The BANFF 2007 Working Classification of Skin-containing Composite Tissue Allograft Pathology. American Journal of Transplantation, 8(7):1396–400.Google Scholar
Morelon, E, Kanitakis, J, Petruzzo, P. 2012. Immunological Issues in Clinical Composite Tissue Allotransplantation: Where Do We Stand Today? Transplantation, 93(9):855–9.Google Scholar
Weissenbacher, A, et al. (2013). Vascularized Composite Allografts and Solid Organ Transplants: Similarities and Differences. Curr Opin Organ Transplant, 18(6): 640644.Google Scholar

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