Skip to main content Accessibility help
×
  1. Home
  2. Browse subjects
  3. Life Sciences
  4. Genetics
  5. Content listing

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

83 results in Genetics

Page 1 of 5

Sex, Genes and Chromosomes
  • Their Discovery, Function and Evolution
  • Jennifer A. Marshall Graves
  • Expected online publication date:
    March 2026
    Print publication:
    19 March 2026
  • Biological sex is central to our continued existence. Yet the mechanism that determines sex, rather than being rational and conserved, is a battlefield of warring genes, sexual antagonism, unbalanced expression and self-destructing sex chromosomes that come in bewildering varieties.Drawing on 50 years of research in three fields in which the author has played key roles, this unique book explores the function, activity and evolution of sex genes and chromosomes in humans and other animals. Providing eye-witness stories of early discoveries and modern genomic insights, it examines how genes and chromosomes determine sex; delving into key breakthroughs, theories on gene and chromosome function, and the enormous scope for variation in body traits and behaviour.Reflecting the huge advances in genetics and genomics that help explain the wonders of human existence and evolution, this book is a fascinating resource for anyone interested in the biology of sex– particularly students and researchers in reproduction, genetics and evolution.

Understanding the Nature‒Nurture Debate
  • Eric Turkheimer
  • Published online:
    07 November 2024
    Print publication:
    21 November 2024
  • There are arguably few areas of science more fiercely contested than the question of what makes us who we are. Are we products of our environments or our genes? Is nature the governing force behind our behaviour or is it nurture? While it is now widely agreed that it is a mixture of both, discussions continue as to which is the dominant influence. This unique volume presents a clear explanation of heritability, the ongoing nature versus nurture debate and the evidence that is currently available. Starting at the beginning of the modern nature-nurture debate, with Darwin and Galton, this book describes how evolution posed a challenge to humanity by demonstrating that humans are animals, and how modern social science was necessitated when humans became an object of natural science. It clearly sets out the most common misconceptions such as the idea that heritability means that a trait is 'genetic' or that it is a justification for eugenics.

The Great Sea Floods of 1953
  • The Records of P. J. O. (John) Trist
  • Edited by Denise Parkinson
  • Published by:
    Boydell & Brewer
    Published online:
    09 May 2024
    Print publication:
    28 May 2024
  • A rare source, transcribed: stories, statistics, meticulous maps by John Trist, 'Mr. Agriculture' to Suffolk's farming community, reveal new insights into forgotten rural history of 1953 East Coast Floods.

Understanding Obesity
  • Stanley Ulijaszek
  • Published online:
    04 January 2024
    Print publication:
    25 January 2024
  • Most people have some dissatisfaction or concern about body weight, fatness, or obesity, either personally or professionally. This book shows how the popular understanding of obesity is often at odds with scientific understandings, and how misunderstandings about people with obesity can further contribute to the problem. It describes, in an approachable way, interconnected debates about obesity in public policy, medicine and public health, and how media and social media engage people in everyday life in those debates. In chapters considering body fat and fatness, genetics, metabolism, food and eating, inequality, blame and stigma, and physical activity, this book brings separate domains of obesity research into the field of complexity. By doing so, it aids navigation through the minefield of misunderstandings about body weight, fatness, and obesity that exist today, after decades of mostly failed policies and interventions.

Understanding Living Systems
  • Raymond Noble, Denis Noble
  • Published online:
    22 June 2023
    Print publication:
    06 July 2023
  • Life is definitively purposive and creative. Organisms use genes in controlling their destiny. This book presents a paradigm shift in understanding living systems. The genome is not a code, blueprint or set of instructions. It is a tool orchestrated by the system. This book shows that gene-centrism misrepresents what genes are and how they are used by living systems. It demonstrates how organisms make choices, influencing their behaviour, their development and evolution, and act as agents of natural selection. It presents a novel approach to fundamental philosophical and cultural issues, such as free-will. Reading this book will make you see life in a new light, as a marvellous phenomenon, and in some sense a triumph of evolution. We are not in our genes, our genes are in us.

An Introduction to Genetic Engineering
  • 4th edition
  • Desmond S. T. Nicholl
  • Published online:
    10 February 2023
    Print publication:
    02 March 2023
  • The fourth edition of this popular textbook retains its focus on the fundamental principles of gene manipulation, providing an accessible and broad-based introduction to the subject for beginning undergraduate students. It has been brought thoroughly up to date with new chapters on the story of DNA and genome editing, and new sections on bioethics, significant developments in sequencing technology and structural, functional and comparative genomics and proteomics, and the impact of transgenic plants. In addition to chapter summaries, learning objectives, concept maps, glossary and key word lists the book now also features new concluding sections, further reading lists and web-search activities for each chapter to provide a comprehensive suite of learning resources to help students develop a flexible and critical approach to the study of genetic engineering.

Textbook of Human Reproductive Genetics
  • 2nd edition
  • Edited by Stéphane Viville, Karen D. Sermon
  • Published online:
    15 December 2022
    Print publication:
    05 January 2023
  • A basic understanding of human genetics is vital for all those working in the field of assisted human reproduction. Genetic makeup can hamper reproduction and insight into this is making genetic diagnosis and counselling increasingly important. This fully updated textbook continues the clear structure of the original edition, beginning with a chapter on the basics of genetics and cytogenetics. Genetic causes of infertility and the effect of epigenetics and transposons on fertility are discussed in detail. Several new chapters are included in this edition, reflecting the advances of the field, including preconception genetic analysis and screening in IVF and mitochondrial genetics. Combining genetics, reproductive biology and medicine, this is an essential text for practitioners in reproductive medicine and geneticists involved in the field looking to improve their knowledge of the subject and provide outstanding patient care.

Why DNA?
  • From DNA Sequence to Biological Complexity
  • Andrew Travers
  • Published online:
    05 May 2022
    Print publication:
    17 February 2022
  • Information is central to the evolution of biological complexity, a physical system relying on a continuous supply of energy. Biology provides superb examples of the consequent Darwinian selection of mechanisms for efficient energy utilisation. Genetic information, underpinned by the Watson-Crick base-pairing rules is largely encoded by DNA, a molecule uniquely adapted to its roles in information storage and utilisation.This volume addresses two fundamental questions. Firstly, what properties of the molecule have enabled it to become the predominant genetic material in the biological world today and secondly, to what extent have the informational properties of the molecule contributed to the expansion of biological diversity and the stability of ecosystems. The author argues that bringing these two seemingly unrelated topics together enables Schrödinger's What is Life?, published before the structure of DNA was known, to be revisited and his ideas examined in the context of our current biological understanding.

Understanding Metaphors in the Life Sciences
  • Andrew S. Reynolds
  • Published online:
    11 April 2022
    Print publication:
    28 April 2022
  • Covering a range of metaphors from a diverse field of sciences, from cell and molecular biology to evolution, ecology, and biomedicine, Understanding Metaphors in the Life Sciences explores the positive and negative implications of the widespread use of metaphors in the biological and life sciences. From genetic codes, programs, and blueprints, to cell factories, survival of the fittest, the tree of life, selfish genes, and ecological niches, to genome editing with CRISPR's molecular scissors, metaphors are ubiquitous and vital components of the modern life sciences. But how exactly do metaphors help scientists to understand the objects they study? How can they mislead both scientists and laypeople alike? And what should we all understand about the implications of science's reliance on metaphorical speech and thought for objective knowledge and adequate public policy informed by science? This book will literally help you to better understand the metaphorical dimensions of science.

Foundations of Behavior Genetics
  • Scott F. Stoltenberg
  • Published online:
    31 March 2022
    Print publication:
    07 July 2022
  • Foundations of Behavior Genetics provides a forward-looking introduction to this fascinating field. Written by an experienced teacher and researcher, this text focuses on concepts, methods, and findings that inform our understanding of heredity–behavior relations. The book's neuroscience perspective asks students to think about potential neural mechanisms involved in pathways from genes to behavior. While the text is primarily focused on human behavior genetics, it also emphasizes the importance of non-human animal models in experimental studies, as well as their evolutionary connections to humans. Part I covers the history of behavior genetics and the basics of non-molecular genetics; Part II discusses molecular genetics and neurogenetics; Part III addresses various behavioral disorders; and Part IV explores health, social behavior, and ethical implications. The text includes detailed chapter summaries, several “Check-up” questions after major sections that test student understanding, and recommended readings. Instructors are provided with a test bank of multiple-choice items and hi-res JPEGs of the many illustrations created for the book.

Understanding Genes
  • Kostas Kampourakis
  • Published online:
    17 February 2022
    Print publication:
    04 November 2021
  • What are genes? What do genes do? These questions are not simple and straightforward to answer; at the same time, simplistic answers are quite prevalent and are taken for granted. This book aims to explain the origin of the gene concept, its various meanings both within and outside science, as well as to debunk the intuitive view of the existence of 'genes for' characteristics and disease. Drawing on contemporary research in genetics and genomics, as well as on ideas from history of science, philosophy of science, psychology and science education, it explains what genes are and what they can and cannot do. By presenting complex concepts and research in a comprehensible and rigorous manner, it examines the potential impact of research in genetics and genomics and how important genes actually are for our lives. Understanding Genes is an accessible and engaging introduction to genes for any interested reader.

New War Technologies and International Law
  • The Legal Limits to Weaponising Nanomaterials
  • Kobi Leins
  • Published online:
    20 January 2022
    Print publication:
    03 February 2022
  • The desire for humanity and the desire for security have co-existed as long as humans have been alive. As science has become increasingly sophisticated, so have the methods of self-defence by States. Nanotechnology is already changing warfare by increasing capabilities upon which armed forces are heavily reliant: more efficient energy storage, advanced photovoltaics, and improved military protective equipment to name a few of these developments. Some applications of nanomaterials by the military are both powerful and subtle, and have neurological and biological applications: 'devices that can infiltrate electronics and seize control at crucial moments, artificial “disease” agents that can rest harmlessly in victims' bodies until activated by an external signal'. The advance of the use or contemplation of use of these types of nanoscale applications by the military requires urgent analysis in light of existing international law, particularly in light of their potential effects on humans and on the environment.

The Genetics of African Populations in Health and Disease
  • Edited by Muntaser E. Ibrahim, Charles N. Rotimi
  • Published online:
    02 December 2019
    Print publication:
    19 December 2019
  • The birthplace of modern humans, Africa, has the highest genetic diversity in the world, yet it remains vastly understudied. With biomedical research increasingly focused on human variation, studying the large population size and number of mutations in African genomes could unravel the complexity of phenotypic traits underlying the biology of our species and hold huge potential for scientific and medical advances. An initial chapter 'conceptualizes Africa', providing relevant terminology. The first section covers genetic history and population structure. The next section looks at the genetic basis of common infectious diseases, such as leishmaniasis, malaria and tuberculosis, with a final part considering common non-communicable diseases, such as diabetes, hypertension, obesity, heart disease and cancer. Gene environment interaction under globalization and the burden of diseases of lifestyle are included. For researchers and graduate students in biological anthropology, genetic anthropology, human and population genetics, and public health.

Phylogenetic Inference, Selection Theory, and History of Science
  • Selected Papers of A. W. F. Edwards with Commentaries
  • Edited by Rasmus Grønfeldt Winther
  • Published online:
    29 June 2018
    Print publication:
    19 July 2018
  • A. W. F. Edwards is one of the most influential mathematical geneticists in the history of the discipline. One of the last students of R. A. Fisher, Edwards pioneered the statistical analysis of phylogeny in collaboration with L. L. Cavalli-Sforza, and helped establish Fisher's concept of likelihood as a standard of statistical and scientific inference. In this book, edited by philosopher of science Rasmus Grønfeldt Winther, Edwards's key papers are assembled alongside commentaries by leading scientists, discussing Edwards's influence on their own research and on thinking in their field overall. In an extensive interview with Winther, Edwards offers his thoughts on his contributions, their legacy, and the context in which they emerged. This book is a resource both for anyone interested in the history and philosophy of genetics, statistics, and science, and for scientists seeking to develop new algorithmic and statistical methods for understanding the genetic relationships between and among species both extant and extinct.

Optogenetics
  • From Neuronal Function to Mapping and Disease Biology
  • Edited by Krishnarao Appasani
  • Published online:
    28 April 2017
    Print publication:
    27 April 2017
  • Discovered little more than a decade ago, optogenetics - a revolutionary technique combining genetic and optical methods to observe and control the function of neurons - is now a widely used research tool. Optogenetics-driven research has led to insights into Parkinson's disease and other neurological and psychiatric disorders. With contributions from leaders and innovators from both academia and industry, this volume explores the discovery and application of optogenetics, from the basic science to its potential clinical use. Chapters cover a range of optogenetics applications, including for brain circuits, plasticity, memory, learning, sleep, vision and neurodegenerative and neuropsychiatric diseases. Providing authoritative coverage of the huge potential that optogenetics research carries, this is an ideal resource for researchers and graduate students, as well as for those working in the biotechnology and pharmaceutical industries and in a clinical setting.

Making Sense of Genes
  • Kostas Kampourakis
  • Published online:
    13 April 2017
    Print publication:
    30 March 2017
  • What are genes? What do genes do? These seemingly simple questions are in fact challenging to answer accurately. As a result, there are widespread misunderstandings and over-simplistic answers, which lead to common conceptions widely portrayed in the media, such as the existence of a gene 'for' a particular characteristic or disease. In reality, the DNA we inherit interacts continuously with the environment and functions differently as we age. What our parents hand down to us is just the beginning of our life story. This comprehensive book analyses and explains the gene concept, combining philosophical, historical, psychological and educational perspectives with current research in genetics and genomics. It summarises what we currently know and do not know about genes and the potential impact of genetics on all our lives. Making Sense of Genes is an accessible but rigorous introduction to contemporary genetics concepts for non-experts, undergraduate students, teachers and healthcare professionals.

Elemente der exakten Erblichkeitslehre
  • Deutsche wesentlich erweiterte Ausgabe in fünfundzwanzig Vorlesungen
  • Wilhelm Johannsen
  • Published online:
    05 June 2016
    Print publication:
    21 May 2015
    First published in:
    1909
  • The Danish plant scientist Wilhelm Johannsen (1857–1927) is remembered for his experimental work on plant heredity, and as a founding figure of modern genetics. The terms 'gene', 'genotype' and 'phenotype' were first used by him. The results of his studies on beans supported theories advanced during the 1890s by the Dutch botanist Hugo de Vries, who had unknowingly replicated the work of Gregor Mendel, published in English translation in 1902 (also reissued in this series) by William Bateson. Johannsen's proposal that changes in heredity resulted from sudden mutations rather than from slow processes of natural selection was seen at the time as a threat to Darwinian theory, though later research showed otherwise. This influential book, first published in 1909 (with later editions in 1913 and 1926), is a revised, expanded German translation of a 1905 Danish book by Johannsen, itself based on a journal article originally published in 1903.

Genome-Wide Association Studies
  • From Polymorphism to Personalized Medicine
  • Edited by Krishnarao Appasani
  • Foreword by Stephen W. Scherer, Peter M. Visscher
  • Published online:
    18 December 2015
    Print publication:
    14 January 2016
  • Over the last twenty years, genome-wide association studies (GWAS) have revealed a great deal about the genetic basis of a wide range of complex diseases and they will undoubtedly continue to have a broad impact as we move to an era of personalised medicine. This authoritative text, written by leaders and innovators from both academia and industry, covers the basic science as well as the clinical, biotechnological and pharmaceutical potential of these methods. With special emphasis given to highlighting pharmacogenomics and population genomics studies using next-generation technology approaches, this is the first book devoted to combining association studies with single nucleotide polymorphisms, copy number variants, haplotypes and expressed quantitative trait loci. A reliable guide for newcomers to the field as well as for experienced scientists, this is a unique resource for anyone interested in how the revolutionary power of genomics can be applied to solve problems in complex disease.

Systems Genetics
  • Linking Genotypes and Phenotypes
  • Edited by Florian Markowetz, Michael Boutros
  • Published online:
    05 July 2015
    Print publication:
    02 July 2015
  • Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies.

Population Genetics for Animal Conservation
  • Giorgio Bertorelle, Michael W. Bruford, Heidi C. Hauffe, Annapaolo Rizzoli, Cristiano Vernesi
  • Published online:
    05 July 2015
    Print publication:
    28 May 2009
  • It is widely accepted among conservation biologists that genetics is, more than ever, an essential and efficient tool for wild and captive population management and reserve design. However, a true synergy between population genetics and conservation biology is lacking. Following the first International Workshop on Population Genetics for Animal Conservation in 2003 at the Centro di Ecologia Alpina, Trento, Italy (recently incorporated into the Edmund Mach Foundation), the scientific committee felt that, given the global urgency of animal conservation, it was imperative that discussions at the conference were made accessible to graduate students and wildlife managers. This book integrates 'the analytical methods approach' with the 'real problems approach' in conservation genetics. Each chapter is an exhaustive review of one area of expertise, and a special effort has been made to explain the statistical tools available for the analysis of molecular data as clearly as possible. The result is a comprehensive volume of the state of the art in conservation genetics, illustrating the power and utility of this synergy.

Page 1 of 5