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Obesity and metabolic syndrome in Brazilian patients with bipolar disorder

Published online by Cambridge University Press:  24 June 2014

Karla Mathias de Almeida ,
Márcia B. de Macedo-Soares ,
Cilly Kluger Issler ,
José Antonio Amaral ,
Sheila C. Caetano ,
Rodrigo da Silva Dias  and
Beny Lafer
Karla Mathias de Almeida*
Affiliation:
Bipolar Disorder Research Program (PROMAN), Institute of Psychiatry, University of São Paulo School of Medicine, São Paulo, Brazil
Márcia B. de Macedo-Soares
Affiliation:
Bipolar Disorder Research Program (PROMAN), Institute of Psychiatry, University of São Paulo School of Medicine, São Paulo, Brazil
Cilly Kluger Issler
Affiliation:
Bipolar Disorder Research Program (PROMAN), Institute of Psychiatry, University of São Paulo School of Medicine, São Paulo, Brazil
José Antonio Amaral
Affiliation:
Bipolar Disorder Research Program (PROMAN), Institute of Psychiatry, University of São Paulo School of Medicine, São Paulo, Brazil
Sheila C. Caetano
Affiliation:
Bipolar Disorder Research Program (PROMAN), Institute of Psychiatry, University of São Paulo School of Medicine, São Paulo, Brazil
Rodrigo da Silva Dias
Affiliation:
Bipolar Disorder Research Program (PROMAN), Institute of Psychiatry, University of São Paulo School of Medicine, São Paulo, Brazil
Beny Lafer
Affiliation:
Bipolar Disorder Research Program (PROMAN), Institute of Psychiatry, University of São Paulo School of Medicine, São Paulo, Brazil
*
Karla Mathias de Almeida, Programa de Transtorno Bipolar (PROMAN), Rua Dr Oví dio Pires de Campos, 785, São Paulo, SP, 05403—010, Brazil. Tel/Fax: 55 11 3069-7928; E-mail: kalmeida@uol.com.br
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Abstract

Objective:

We aimed to determine the prevalence of obesity and metabolic syndrome (O/MetS) in a sample of Brazilian outpatients with bipolar disorder.

Methods:

Eighty-four patients with bipolar disorder were evaluated. We used the definition of MetS established in the Third Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults, modified by the American Heart Association (AHA). Patients were classified as obese if their body mass index (BMI) was ≥ 30 kg/m2.

Results:

We found that 28.6% of our sample met the AHA criteria for MetS and 35.7% were obese. The percentage of patients meeting each criterion of the AHA was as follows: 46% for abdominal obesity; 44% for hypertriglyceridemia or cholesterol-lowering medication use; 26% for low high-density lipoprotein cholesterol or being on a lipid-lowering medication; 45% for hypertension; and 20% for high fasting glucose or anti-diabetic medication use.

Conclusions:

The prevalence of obesity in our sample of outpatients with bipolar disorder was higher than that observed for the general population of Brazil. The rate of MetS was similar to that observed for the general population. Our data indicate the need for prevention, early detection and treatment of O/MetS in patients with bipolar disorder.

Keywords

bipolar disorderdiabetesdyslipidemiainsulin resistancemetabolic syndromeobesity
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 21 , Issue 2 , April 2009 , pp. 84 - 88
Copyright
Copyright © 2009 Blackwell Munksgaard

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