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Association of demographic, lifestyle factors and serum biomarkers with hypertension in elderly Chinese people

  • XIUQIN HONG (a1), NUALNONG WONGTONGKAM (a2), PAUL RUSSELL WARD (a3), SHUIYUAN XIAIO (a4), SHULING WANG (a5), QIAN PENG (a5), QI ZUO (a5), DAN ZENG (a5), JIA WANG (a5) and CHENXU WANG (a5)...
Abstract

Hypertension is a major cause of premature death in China. Understanding risk factors including behavioural and predisposing factors may help to prevent development of hypertension and control the extent of premature mortality. In this case-control design conducted in Hunan province, 416 hypertensive subjects were matched with an equal number of normotensive persons from nearly 9,000 volunteers. A self-report questionnaire was employed to collect demographic and lifestyle information, and fasting serum biomarkers related to lipid profile, renal function, glucose level and uric acid were assessed. When age and sex were stratified, serum biomarkers such as blood urea nitrogen and triglycerides showed a significant difference for hypertension, while lifestyle behaviours including university degree, alcohol use, Body Mass Index and psychological stress (job and married life) were also associated with hypertension. After adjusting for covariate confounding factors, only elevated triglyceride levels were strongly linked to high blood pressure, odds ratio = 1.55, 95 per cent confidence level = 1.16–2.06. To control high blood pressure, hypertriglyceridemia should be included in hypertension treatment and followed up to assess the substantial risk of cardiovascular diseases.

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Corresponding author
Address for correspondence: Nualnong Wongtongkam, School of Biomedical Sciences, Charles Sturt University, 1448-Building, Bathurst, NSW 2795, Australia E-mail: nwongtongkam@csu.edu.au
References
Hide All
Cheng, T. O. 2005. Rising cholesterol levels in China. International Journal of Cardiology, 105, 3, 332–3.
Cheng, T. O. 2006. Effects of fast foods, rising blood pressure and increasing serum cholesterol on cardiovascular disease in China. American Journal of Cardiology, 97, 11, 1676–8.
China Population and Development Research Center 2012. People's University of China. Haidian District, Beijing, China. Available online at http://www.cpdrc.org.cn. [10 February 2015].
Chinese Nutrition Society, National Institute of Nutrition and Food Safety of China CDC, 2007. Dietary Guidelines for Chinese Residents. Available online at http://www.cnsoc.org/cn/nutrition. [12 February 2015].
Chobanian, A. V., Bakris, G. L., Black, H. R., Cushman, W. C., Green, L. A., Izzo, J. L. Jr, Jones, D. W., Materson, B. J., Oparil, S., Wright, J. T. Jr, Roccella, E. J. 2003. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA: The Journal of the American Medical Association, 289, 19, 2560–72.
Cui, Z., Huxley, R., Wu, Y. and Dibley, M. J. 2010. Temporal trends in overweight and obesity of children and adolescents from nine provinces in China from 1991–2006. International Journal of Pediatric Obesity, 5, 5, 365–74.
French, S. A., Harnack, L. and Jeffery, R. W. 2000. Fast food restaurant use among women in the Pound of Prevention study: dietary, behavioral and demographic correlates. International Journal of Obesity and Related Metabolic Disorders, 24, 10, 1353–9.
Frontini, M. G., Srinivasan, S. R., Elkasabany, A. and Berenson, G. S. 2001. Distribution and cardiovascular risk correlates of serum triglycerides in young adults from a biracial community: the Bogalusa Heart Study. Atherosclerosis, 155, 1, 201–9.
Gould, B. W. 2002. Household composition and food expenditures in China. Agribusiness, 18, 3, 387407.
Grundy, S. M. 1998. Hypertriglyceridemia, atherogenic dyslipidemia, and the metabolic syndrome. American Journal of Cardiology, 81, 4A, 18B25B.
He, J., Gu, D., Wu, X., Reynolds, K., Duan, X., Yao, C., Wang, J., Chen, C. S., Chen, J., Wildman, R. P., Klaq, M. J. and Whelton, P. K. 2005. Major causes of death among men and women in China. New England Journal of Medicine, 353, 11, 1124–34.
He, J. and Whelton, P. K. 1997. Epidemiology and prevention of hypertension. Medical Clinics of North America, 81, 5, 1077–97.
Ibrahim, M. M. and Damasceno, A. 2012. Hypertension in developing countries. Lancet, 380, 9841, 611–9.
Jeffery, R. W. and French, S. A. 1998. Epidemic obesity in the United States: are fast foods and television viewing contributing? American Journal of Public Health, 88, 2, 277–80.
Joshipura, K. J., Hu, F. B., Manson, J. E., Stampfer, M. J., Rimm, E. B., Speizer, F. E., Colditz, G., Ascherio, A., Spieqelman, D. and Willett, W. C. 2001. The effect of fruit and vegetable intake on risk for coronary heart disease. Annals of Internal Medicine, 134, 12, 1106–14.
Kearney, P. M., Whelton, M., Reynolds, K., Muntner, P., Whelton, P. K. and He, J. 2005. Global burden of hypertension: analysis of worldwide data. Lancet, 365, 9455, 217–23.
Laaksonen, D. E., Niskanen, L., Nyyssonen, K., Lakka, T. A., Laukkanen, J. A. and Salonen, J. T. 2008. Dyslipidaemia as a predictor of hypertension in middle-aged men. European Heart Journal, 29, 20, 2561–8.
Li, Y., Li, D., Ma, C. Y., Liu, C. Y., Hui, D., Wen, Z. M. and Peng, L. P. 2012. Consumption of, and factors influencing consumption of, fruit and vegetables among elderly Chinese people. Nutrition, 28, 5, 504–8.
Liu, L. 2007. Cardiovascular diseases in China. Biochemistry and Cell Biology, 85, 2, 157–63.
Ma, H., Rae, A., Huang, J. and Rozelle, S. 2004. Chinese animal product consumption in the 1990s. Australian Journal of Agricultural and Resource Economics, 48, 4, 569–90.
Mendez, M. and Popkin, B. 2004. Globalization, urbanization and nutritional change in the developing world. Electronic Journal of Agricultural and Development Economics, 1, 2, 220–41.
Ministry of Public Health 2004. Chinese Public Health Statistics Year Book 2004. Peking Union Medical College Press, Beijing.
National Center for Cardiovascular Disease, Drafting Committee of Chinese Guideline for Hypertension Management 2005. Guideline for hypertension management. Chinese Journal of Hypertension, 13, supplement, 341.
Niskanen, L., Laaksonen, D. E., Nyyssönen, K., Punnonen, K., Valkonen, V. P., Fuentes, R., Tuomainen, T. P., Salonen, R., Salonen, J. T. 2004. Inflammation, abdominal obesity, and smoking as predictors of hypertension. Hypertension, 44, 6, 859–65.
Pingali, P. 2006. Westernization of Asian diets and the transformation of food systems: implications for research and policy. Food Policy, 32, 3, 281–98.
Reynolds, K., Gu, D., Whelton, P. K., Wu, X., Duan, X., Mo, J., He, J. and InterASIA Collaborative Group. 2007. Prevalence and risk factors of overweight and obesity in China. Obesity, 15, 1, 1018.
Smith, J. P., Strauss, J. and Zhao, Y. 2014. Healthy aging in China. Journal of the Economics of Ageing, 4, 3743.
Song, A., Liang, Y., Yan, Z., Sun, B., Cai, C., Jiang, H. and Qiu, C. 2014. Highly prevalent and poorly controlled cardiovascular risk factors among Chinese elderly people living in the rural community. European Journal of Preventive Cardiology, 21, 10, 1267–74.
Ting, H. J., Stice, J. P., Schaff, U. Y., Hui, D. Y., Rutledge, J. C., Knowlton, A. A., Passerini, A. G. and Simon, S. I. 2007. Triglyceride-rich lipoproteins prime aortic endothelium for an enhanced inflammatory response to tumor necrosis factor-alpha. Circulation Research, 100, 3, 381–90.
Utsugi, M. T., Ohkubo, T., Kikuya, M., Kurimoto, A., Sato, R. I., Suzuki, K., Metoki, H., Tsubono, Y. and Imai, Y. 2008. Fruit and vegetable consumption and the risk of hypertension determined by self measurement of blood pressure at home: the Ohasama study. Hypertension Research, 31, 7, 1435–43.
Veeck, A. and Veeck, G. 2000. Consumer segmentation and changing food purchase patterns in Nanjing, PRC. World Development, 28, 3, 457–71.
Watson, J. L. 1997. Introduction: transnationalism, localization, and fast foods in East Asia. In Watson, J. L. (ed.), Golden Arches East McDonald's in East Asia. Stanford University Press, Stanford, California. pp 110.
Wu, Y., Huxley, R., Li, L., Anna, V., Xie, G., Yao, C., Woodward, M., Li, X., Chalmers, J., Gao, R., Kong, L., Yang, X., China NNHS Steering Committee and China NNHS Working Group 2008. Prevalence, awareness, treatment, and control of hypertension in China: data from the China National Nutrition and Health Survey 2002. Circulation, 118, 25, 2679–86.
Yan, Y. 1997. McDonald's in Beijing: the localization of Americana. In Watson, J. L. (ed.), Golden Arches East McDonald's in East Asia. Stanford University Press, Stanford, California. pp. 3945.
Yang, G., Wang, Y., Zeng, Y., Gao, G. F., Liang, X., Zhou, M., Wan, X., Yu, S., Jiang, Y., Naghavi, M., Vos, T., Wang, H., Lopez, A. D., Murray, C. J. 2013. Rapid health transition in China, 1990–2010: findings from the Global Burden of Disease Study 2010. Lancet, 381, 9882, 19872015.
Yki-Jarvinen, H. and Taskinen, M. R. 1988. Interrelationships among insulin's antilipolytic and glucoregulatory effects and plasma triglycerides in nondiabetic and diabetic patients with endogenous hypertriglyceridemia. Diabetes, 37, 9, 1271–8.
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Ageing & Society
  • ISSN: 0144-686X
  • EISSN: 1469-1779
  • URL: /core/journals/ageing-and-society
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