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Avian influenza: our current understanding

  • David L. Suarez (a1)
Abstract

Avian influenza (AI) virus is one of the most important diseases of the poultry industry around the world. The virus has a broad host range in birds and mammals, although the natural reservoir is wild birds where it typically causes an asymptomatic to mild infection. The virus in poultry can cause a range of clinical diseases and is defined either as low pathogenic AI (LPAI) or highly pathogenic AI (HPAI) depending on the type of disease it causes in chickens. Viruses that replicate primarily on mucosal surfaces and cause mild disease with low mortality are termed LPAI. Viruses that replicate on mucosal surfaces and systemically and cause severe disease with a mortality rate of 75% or greater in experimentally infected chickens are referred to as HPAI. A virus that is highly pathogenic in chickens may infect but result in a completely different disease and replication pattern in other host species. Outbreaks of HPAI have been relatively uncommon around the world in the last 50 years and have had limited spread within a country or region with one major exception, Asian lineage H5N1 that was first identified in 1996. This lineage of virus has spread to over 60 countries and has become endemic in poultry in at least four countries. AI virus also represents a public health threat, with some infected humans having severe disease and with a high case fatality rate. AI remains a difficult disease to control because of the highly infectious nature of the virus and the interface of domestic and wild animals. A better understanding of the disease and its transmission is important for control.

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Alexander, DJ (2007). Summary of avian influenza activity in Europe, Asia, Africa, and Australasia, 2002–2006. Avian Diseases 51 (suppl. 1): 161166.
Becker, WB (1966). The isolation and classification of Tern virus: influenza A-Tern South Africa 1961. Journal of Hygiene (London) 64: 309320.
Brown, JD, Goekjian, G, Poulson, R, Valeika, S and Stallknecht, DE (2009a). Avian influenza virus in water: infectivity is dependent on pH, salinity and temperature. Veterinary Microbiology 136: 2026.
Brown, JD, Stallknecht, DE, Beck, JR, Suarez, DL and Swayne, DE (2006). Susceptibility of North American ducks and gulls to H5N1 highly pathogenic avian influenza viruses. Emerging Infectious Diseases 12: 16631670.
Brown, JD, Stallknecht, DE, Berghaus, RD and Swayne, DE (2009b). Infectious and lethal doses of H5N1 highly pathogenic avian influenza virus for house sparrows (Passer domesticus) and rock pigeons (Columbia livia). Journal of Veterinary Diagnostic Investigation 21: 437445.
Brown, JD, Stallknecht, DE and Swayne, DE (2008). Experimental infection of swans and geese with highly pathogenic avian influenza virus (H5N1) of Asian lineage. Emerging Infectious Diseases 14: 136142.
Brown, JD, Stallknecht, DE, Valeika, S and Swayne, DE (2007). Susceptibility of wood ducks to H5N1 highly pathogenic avian influenza virus. Journal of Wildlife Diseases 43: 660667.
Bulaga, LL, Garber, L, Senne, DA, Myers, TJ, Good, R, Wainwright, S, Trock, S and Suarez, DL (2003). Epidemiologic and surveillance studies on avian influenza in live-bird markets in New York and New Jersey, 2001. Avian Diseases 47 (suppl. 3): 9961001.
Capua, I and Mutinelli, F (2001). Mortality in Muscovy ducks (Cairina moschata) and domestic geese (Anser anser var. domestica) associated with natural infection with a highly pathogenic avian influenza virus of H7N1 subtype. Avian Pathology 30: 179183.
Cauthen, AN, Swayne, DE, Schultz-Cherry, S, Perdue, ML and Suarez, DL (2000). Continued circulation in China of highly pathogenic avian influenza viruses encoding the hemagglutinin gene associated with the 1997 H5N1 outbreak in poultry and humans. Journal of Virology 74: 65926599.
Centers for Disease Control and Prevention (CDC) (2004). Outbreaks of avian influenza A (H5N1) in Asia and interim recommendations for evaluation and reporting of suspected cases – United States, 2004. Morbidity Mortality Weekly Reports 53: 97100.
Chen, H, Deng, G, Li, Z, Tian, G, Li, Y, Jiao, P, Zhang, L, Liu, Z, Webster, RG and Yu, K (2004). The evolution of H5N1 influenza viruses in ducks in southern China. Proceedings of the National Academy of Sciences, USA 101: 1045210457.
Chen, H, Li, Y, Li, Z, Shi, J, Shinya, K, Deng, G, Qi, Q, Tian, G, Fan, S, Zhao, H, Sun, Y and Kawaoka, Y (2006a). Properties and dissemination of H5N1 viruses isolated during an influenza outbreak in migratory waterfowl in western China. Journal of Virology 80: 59765983.
Chen, H, Matsuoka, Y, Swayne, D, Chen, Q, Cox, NJ, Murphy, BR and Subbarao, K (2003). Generation and characterization of a cold-adapted influenza A H9N2 reassortant as a live pandemic influenza virus vaccine candidate. Vaccine 21: 44304436.
Chen, H, Smith, GJ, Li, KS, Wang, J, Fan, XH, Rayner, JM, Vijaykrishna, D, Zhang, JX, Zhang, LJ, Guo, CT, Cheung, CL, Xu, KM, Duan, L, Huang, K, Qin, K, Leung, YH, Wu, WL, Lu, HR, Chen, Y, Xia, NS, Naipospos, TS, Yuen, KY, Hassan, SS, Bahri, S, Nguyen, TD, Webster, RG, Peiris, JS and Guan, Y (2006b). Establishment of multiple sublineages of H5N1 influenza virus in Asia: implications for pandemic control. Proceedings of the National Academy of Sciences, USA 103: 28452850.
Chen, H, Smith, GJ, Zhang, SY, Qin, K, Wang, J, Li, KS, Webster, RG, Peiris, JS and Guan, Y (2005). Avian flu: H5N1 virus outbreak in migratory waterfowl. Nature 436: 191192.
Choi, YK, Seo, SH, Kim, JA, Webby, RJ and Webster, RG (2005). Avian influenza viruses in Korean live poultry markets and their pathogenic potential. Virology 332: 529537.
Colman, PM (1989). Neuraminidase enzyme and antigen. In: Krug, RM (ed.) The Influenza Viruses. New York: Plenum Press, pp. 175218.
Costa, TP, Brown, JD, Howerth, EW and Stallknecht, DE (2010). The effect of age on avian influenza viral shedding in Mallards (Anas platyrhynchos). Avian Diseases 54: 581585.
Deibel, R, Emord, DE, Dukelow, W, Hinshaw, VS and Wood, JM (1985). Influenza viruses and paramyxoviruses in ducks in the Atlantic flyway, 1977–1983, including an H5N2 isolate related to the virulent chicken virus. Avian Diseases 29: 970985.
Domenech, J, Dauphin, G, Rushton, J, McGrane, J, Lubroth, J, Tripodi, A, Gilbert, J and Sims, LD (2009). Experiences with vaccination in countries endemically infected with highly pathogenic avian influenza: the Food and Agriculture Organization perspective. Revue Scientifique et Technique (International Office of Epizootics) 28: 293305.
Dung Nguyen, T, Vinh Nguyen, T, Vijaykrishna, D, Webster, RG, Guan, Y, Malik Peiris, JS and Smith, GJ (2008). Multiple sublineages of influenza A virus (H5N1), Vietnam, 2005–2007. Emerging Infectious Diseases 14: 632636.
Ellis, TM, Sims, LD, Wong, HK, Wong, CW, Dyrting, KC, Chow, KW, Leung, C and Peiris, JS (2006). Use of avian influenza vaccination in Hong Kong. Developmental Biology (Basel) 124: 133143.
Fang, TH, Lien, YY, Cheng, MC and Tsai, HJ (2006). Resistance of immune-suppressed pigeons to subtypes H5N2 and H6N1 low pathogenic avian influenza virus. Avian Diseases 50: 269272.
Feare, CJ (2010). Role of wild birds in the spread of highly pathogenic avian influenza virus H5N1 and implications for global surveillance. Avian Diseases 54: 201212.
Gilbert, M, Xiao, X, Domenech, J, Lubroth, J, Martin, V and Slingenbergh, J (2006). Anatidae migration in the western Palearctic and spread of highly pathogenic avian influenza H5NI virus. Emerging Infectious Diseases 12: 16501656.
Guan, Y, Peiris, JS, Lipatov, AS, Ellis, TM, Dyrting, KC, Krauss, S, Zhang, LJ, Webster, RG and Shortridge, KF (2002a). Emergence of multiple genotypes of H5N1 avian influenza viruses in Hong Kong, SAR. Proceedings of the National Academy of Science, USA 99: 89508955.
Guan, Y, Peiris, M, Kong, KF, Dyrting, KC, Ellis, TM, Sit, T, Zhang, LJ and Shortridge, KF (2002b). H5N1 influenza viruses isolated from geese in Southeastern China: evidence for genetic reassortment and interspecies transmission to ducks. Virology 292: 1623.
Guan, Y, Poon, LL, Cheung, CY, Ellis, TM, Lim, W, Lipatov, AS, Chan, KH, Sturm-Ramirez, KM, Cheung, CL, Leung, YH, Yuen, KY, Webster, RG and Peiris, JS (2004). H5N1 influenza: a protean pandemic threat. Proceedings of the National Academy of Sciences, USA 101: 81568161.
Guan, Y, Shortridge, KF, Krauss, S and Webster, RG (1999). Molecular characterization of H9N2 influenza viruses: were they the donors of the ‘internal’ genes of H5N1 viruses in Hong Kong? Proceedings of the National Academy of Sciences, USA 96: 93639637.
Halvorson, DA (2008). Control of low pathogenicity avian influenza. In: Swayne, DE (ed) Avian Influenza. Ames, IA: Blackwell Publishing, pp. 513536.
Halvorson, DA, Kelleher, CJ and Senne, DA (1985). Epizootiology of avian influenza: effect of season on incidence in sentinel ducks and domestic turkeys in Minnesota. Applied and Environmental Microbiology 49: 914919.
Hanson, BA, Luttrell, MP, Goekjian, VH, Niles, L, Swayne, DE, Senne, DA and Stallknecht, DE (2008). Is the occurrence of avian influenza virus in Charadriiformes species and location dependent? Journal of Wildlife Diseases 44: 351361.
Harder, TC, Teuffert, J, Starick, E, Gethmann, J, Grund, C, Fereidouni, S, Durban, M, Bogner, KH, Neubauer-Juric, A, Repper, R, Hlinak, A, Engelhardt, A, Nöckler, A, Smietanka, K, Minta, Z, Kramer, M, Globig, A, Mettenleiter, TC, Conraths, FJ and Beer, M (2009). Highly pathogenic avian influenza virus (H5N1) in frozen duck carcasses, Germany, 2007. Emerging Infectious Diseases 15: 272279.
Hatta, M, Hatta, Y, Kim, JH, Watanabe, S, Shinya, K, Nguyen, T, Lien, PS, Le, QM and Kawaoka, Y (2007). Growth of H5N1 influenza A viruses in the upper respiratory tracts of mice. PLoS Pathogens 3: 13741379.
Hill, NJ, Takekawa, JY, Cardona, CJ, Ackerman, JT, Schultz, AK, Spragens, KA and Boyce, WM (2010). Waterfowl ecology and avian influenza in California: do host traits inform us about viral occurrence? Avian Diseases 54: 426432.
Hinshaw, VS, Webster, RG and Turner, B (1979). Water-bone transmission of influenza A viruses? Intervirology 11: 6668.
Hoffmann, E, Stech, J, Leneva, I, Krauss, S, Scholtissek, C, Chin, PS, Peiris, M, Shortridge, KF and Webster, RG (2000). Characterization of the influenza A virus gene pool in avian species in southern China: was H6N1 a derivative or a precursor of H5N1? Journal of Virology 74: 63096315.
Kawaoka, Y, Chambers, TM, Sladen, WL and Webster, RG (1988). Is the gene pool of influenza viruses in shorebirds and gulls different from that in wild ducks? Virology 163: 247250.
L'Vov, DK, Shchelkanov, M, Deriabin, PG, Grebennikova, TV, Prilipov, AG, Nepoklonov, EA, Onishchenko, GG, Vlasov, NA, Aliper, TI, Zaberezhny, AD, Kireev, DE, Krasheninnikov, OP, Kiriukhin, ST, Burtseva, EI and Slepushkin, AN (2006). [Isolation of influenza A/H5N1 virus strains from poultry and wild birds in West Siberia during epizooty (July 2005) and their depositing to the state collection of viruses (August 8, 2005)]. Voprosy Virusologii 51: 111114.
Lau, EH, Leung, YH, Zhang, LJ, Cowling, BJ, Mak, SP, Guan, Y, Leung, GM and Peiris, JS (2007). Effect of interventions on influenza A (H9N2) isolation in Hong Kong's live poultry markets, 1999–2005. Emerging Infectious Diseases 13: 13401347.
Lee, CW and Suarez, DL (2005). Avian influenza virus: prospects for prevention and control by vaccination. Animal Health Research Reviews 6: 115.
Lee, CW, Swayne, DE, Linares, JA, Senne, DA and Suarez, DL (2005). H5N2 avian influenza outbreak in Texas in 2004: the first highly pathogenic strain in the United States in 20 years? Journal of Virology 79: 1141211421.
Li, KS, Guan, Y, Smith, GJ, Xu, KM, Duan, L, Rahardjo, AP, Puthavathana, P, Buranathai, C, Nguyen, TD, Estoepangestie, AT, Chaisingh, A, Auewarakul, P, Long, HT, Hanh, NT, Webby, RJ, Poon, LL, Chen, H, Shortridge, KF, Yuen, KY, Webster, RG and Peiris, JS (2004). Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia. Nature 430: 209213.
Liu, C, Eichelberger, MC, Compans, RW and Air, GM (1995). Influenza type A virus neuraminidase does not play a role in viral entry, replication, assembly, or budding. Journal of Virology 69: 10991106.
Liu, J, Xiao, H, Lei, F, Zhu, Q, Qin, K, Zhang, XW, Zhang, XL, Zhao, D, Wang, G, Feng, Y, Ma, J, Liu, W, Wang, J and Gao, GF (2005). Highly pathogenic H5N1 influenza virus infection in migratory birds. Science 309: 1206.
Liu, M, He, S, Walker, D, Zhou, N, Perez, DR, Mo, B, Li, F, Huang, X, Webster, RG and Webby, RJ (2003). The influenza virus gene pool in a poultry market in South central china. Virology 305: 267275.
Liu, Y, Zhou, J, Yang, H, Yao, W, Bu, W, Yang, B, Song, W, Meng, Y, Lin, J, Han, C, Zhu, J, Ma, Z, Zhao, J and Wang, X (2007). Susceptibility and transmissibility of pigeons to Asian lineage highly pathogenic avian influenza virus subtype H5N1. Avian Pathology 36: 461465.
Long, JX, Peng, DX, Liu, YL, Wu, YT and Liu, XF (2008). Virulence of H5N1 avian influenza virus enhanced by a 15-nucleotide deletion in the viral nonstructural gene. Virus Genes 36: 471478.
Lvov, DK, Shchelkanov, MY, Prilipov, AG, Vlasov, NA, Fedyakina, IT, Deryabin, PG, Alkhovsky, SV, Grebennikova, TV, Zaberezhny, AD and Suarez, DL (2010). Evolution of HPAI H5N1 Virus in Natural Ecosystems of Northern Eurasia (2005–2008). Avian Diseases 54: 483495.
Massin, P, van der Werf, S and Naffakh, N (2001). Residue 627 of PB2 is a determinant of cold sensitivity in RNA replication of avian influenza viruses. Journal of Virology 75: 53985404.
Matrosovich, M, Zhou, N, Kawaoka, Y and Webster, R (1999). The surface glycoproteins of H5 influenza viruses isolated from humans, chickens, and wild aquatic birds have distinguishable properties. Journal of Virology 73: 11461155.
McLeod, A (2008). The economics of avian influenza. In: Swayne, DE (ed) Avian Influenza. Ames, IA, Blackwell Publishing, pp. 537560.
Mitnaul, LJ, Matrosovich, MN, Castrucci, MR, Tuzikov, AB, Bovin, NV, Kobasa, D and Kawaoka, Y (2000). Balanced hemagglutinin and neuraminidase activities are critical for efficient replication of influenza A virus. Journal of Virology 74: 60156020.
Munier, S, Larcher, T, Cormier-Aline, F, Soubieux, D, Su, B, Guigand, L, Labrosse, B, Cherel, Y, Quéré, P, Marc, D and Naffakh, N (2010). A genetically engineered waterfowl influenza virus with a deletion in the stalk of the neuraminidase has increased virulence for chickens. Journal of Virology 84: 940952.
Nakamura, K, Imada, T, Imai, K, Yamamoto, Y, Tanimura, N, Yamada, M, Mase, M, Tsukamoto, K and Yamaguchi, S (2008). Pathology of specific-pathogen-free chickens inoculated with H5N1 avian influenza viruses isolated in Japan in 2004. Avian Diseases 52: 813.
Nguyen, DC, Uyeki, TM, Jadhao, S, Maines, T, Shaw, M, Matsuoka, Y, Smith, C, Rowe, T, Lu, X, Hall, H, Xu, X, Balish, A, Klimov, A, Tumpey, TM, Swayne, DE, Huynh, LP, Nghiem, HK, Nguyen, HH, Hoang, LT, Cox, NJ and Katz, JM (2005). Isolation and characterization of avian influenza viruses, including highly pathogenic H5N1, from poultry in live bird markets in Hanoi, Vietnam, in 2001. Journal of Virology 79: 42014212.
Nguyen, T, Davis, CT, Stembridge, W, Shu, B, Balish, A, Inui, K, Do, HT, Ngo, HT, Wan, XF, McCarron, M, Lindstrom, SE, Cox, NJ, Nguyen, CV, Klimov, AI and Donis, RO (2009). Characterization of a highly pathogenic avian influenza H5N1 virus sublineage in poultry seized at ports of entry into Vietnam. Virology 387: 250256.
Okamatsu, M, Saito, T, Yamamoto, Y, Mase, M, Tsuduku, S, Nakamura, K, Tsukamoto, K and Yamaguchi, S (2007). Low pathogenicity H5N2 avian influenza outbreak in Japan during the 2005–2006. Veterinary Microbiology 124: 3546.
Pantin-Jackwood, M, Wasilenko, JL, Spackman, E, Suarez, DL and Swayne, DE (2010). Susceptibility of turkeys to pandemic-H1N1 virus by reproductive tract insemination. Virology Journal 7: 27.
Pantin-Jackwood, MJ and Swayne, DE (2007). Pathobiology of Asian highly pathogenic avian influenza H5N1 virus infections in ducks. Avian Diseases 51 (suppl. 1): 250259.
Pasick, J, Berhane, Y, Hisanaga, T, Kehler, H, Hooper-McGrevy, K, Handel, K, Neufeld, J, Argue, C and Leighton, F (2010). Diagnostic test results and pathology associated with the 2007 Canadian H7N3 highly pathogenic avian influenza outbreak. Avian Diseases 54: 213219.
Pelzel, AM, McCluskey, BJ and Scott, AE (2006). Review of the highly pathogenic avian influenza outbreak in Texas, 2004. Journal of the American Veterinary Medical Association 228: 18691875.
Perdue, ML (2008). Molecular determinants of pathogencity for avian influenza viruses. In: Swayne, DE (ed.) Avian Influenza. Ames, IA: Blackwell Publishing, pp. 2341.
Perez, DR, Lim, W, Seiler, JP, Yi, G, Peiris, M, Shortridge, KF and Webster, RG (2003a). Role of quail in the interspecies transmission of H9 influenza A viruses: molecular changes on HA that correspond to adaptation from ducks to chickens. Journal of Virology 77: 31483156.
Perez, DR, Webby, RJ, Hoffmann, E and Webster, RG (2003b). Land-based birds as potential disseminators of avian mammalian reassortant influenza A viruses. Avian Diseases 47 (suppl. 3): 11141117.
Perkins, LE and Swayne, DE (2001). Pathobiology of A/chicken/Hong Kong/220/97 (H5N1) avian influenza virus in seven gallinaceous species. Veterinary Pathology 38: 149164.
Perkins, LE and Swayne, DE (2002). Pathogenicity of a Hong Kong-origin H5N1 highly pathogenic avian influenza virus for emus, geese, ducks, and pigeons. Avian Diseases 46: 5363.
Pfeiffer, J, Pantin-Jackwood, M, To, TL, Nguyen, T and Suarez, DL (2009). Phylogenetic and biological characterization of highly pathogenic H5N1 avian influenza viruses (Vietnam 2005) in chickens and ducks. Virus Research 142: 108120.
Pillai, SPS, Pantin-Jackwood, M, Yassine, HM, Saif, YM, and Lee, CW (2010). The high susceptibility of Turkeys to influenza viruses of different origins implies their importance as potential intermediate hosts. Avian Diseases 54: 522526.
Pittman, M and Laddomada, A (2008). Legislation for the control of avian influenza in the European Union. Zoonoses and Public Health 55: 2936.
Ramirez-Nieto, G, Shivaprasad, HL, Kim, C-H, Lillehoj, HS, Song, H, Osorio, IG, and Perez, DR (2010). Adaptation of a mallard H5N2 low pathogenic influenza virus in chickens with prior history of infection with infectious bursal disease virus. Avian Diseases 54: 513521.
Senne, DA (2007). Avian influenza in North and South America, 2002–2005. Avian Diseases 51 (suppl. 1): 167173.
Senne, DA, Pearson, JE and Pahigrahy, B (1992). Live poultry markets: a missing link in the epidemiology of avian influenza. Proceedings of the Third International Symposium on Avian Influenza, Madison, WI, United States Animal Health Association, pp. 5058.
Sharshov, K, Silko, N, Sousloparov, I, Zaykovskaya, A, Shestopalov, A and Drozdov, I (2010). Avian influenza (H5N1) outbreak among wild birds, Russia, 2009. Emerging Infectious Diseases 16: 349351.
Shortridge, KF, Zhou, NN, Guan, Y, Gao, P, Ito, T, Kawaoka, Y, Kodihalli, S, Krauss, S, Markwell, D, Murti, KG, Norwood, M, Senne, D, Sims, L, Takada, A and Webster, RG (1998). Characterization of avian H5N1 influenza viruses from poultry in Hong Kong. Virology 252: 331342.
Sims, LD and Brown, IH (2008). Multicontinental Epidemic of H5N1 HPAI Virus (1996–2007). Ames, IA: Blackwell Publishing.
Sims, LD, Ellis, TM, Liu, KK, Dyrting, K, Wong, H, Peiris, M, Guan, Y and Shortridge, KF (2003). Avian influenza in Hong Kong 1997–2002. Avian Diseases 47 (suppl. 3): 832838.
Sivanandan, V, Halvorson, DA, Laudert, E, Senne, DA and Kumar, MC (1991). Isolation of H13N2 influenza A virus from turkeys and surface water. Avian Diseases 35: 974977.
Slemons, RD, Johnson, DC, Osborn, JS and Hayes, F (1974). Type-A influenza viruses isolated from wild free-flying ducks in California. Avian Diseases 18: 119124.
Slemons, RD, Shieldcastle, MC, Heyman, LD, Bednarik, KE and Senne, DA (1991). Type A influenza viruses in waterfowl in Ohio and implications for domestic turkeys. Avian Diseases 35: 165173.
Sorrell, EM and Perez, DR (2007). Adaptation of influenza A/Mallard/Potsdam/178-4/83 H2N2 virus in Japanese quail leads to infection and transmission in chickens. Avian Diseases 51 (suppl. 1): 264268.
Spackman, E, McCracken, KG, Winker, K and Swayne, DE (2006). H7N3 avian influenza virus found in a South American wild duck is related to the Chilean 2002 poultry outbreak, contains genes from equine and North American wild bird lineages, and is adapted to domestic turkeys. Journal of Virology 80: 77607764.
Spackman, E, McCracken, KG, Winker, K and Swayne, DE (2007a). An avian influenza virus from waterfowl in South America contains genes from North American avian and equine lineages. Avian Diseases 51 (suppl. 1): 273274.
Spackman, E, Senne, DA, Davison, S and Suarez, DL (2003). Sequence analysis of recent H7 avian influenza viruses associated with three different outbreaks in commercial poultry in the United States. Journal of Virology 77: 1339913402.
Spackman, E, Swayne, DE, Suarez, DL, Senne, DA, Pedersen, JC, Killian, ML, Pasick, J, Handel, K, Pillai, SP, Lee, CW, Stallknecht, D, Slemons, R, Ip, HS and Deliberto, T (2007b). Characterization of low pathogenicity H5N1 avian influenza viruses from North America. Journal of Virology 81: 1161211619.
Stallknecht, DE (1998). Ecology and epidemiology of avian influenza viruses in wild bird populations: waterfowl, shorebirds, pelicans, cormorants, etc. Proceedings of the Fourth International Symposium on Avian Influenza, Athens, GA, United States Animal Health Association, pp. 6169.
Stallknecht, DE and Brown, JD (2008). Ecology of avian influenza in wild birds. In: Swayne, DE (ed.) Avian Influenza. Ames, IA: Blackwell Publishing, pp. 4358.
Sturm-Ramirez, KM, Ellis, T, Bousfield, B, Bissett, L, Dyrting, K, Rehg, JE, Poon, L, Guan, Y, Peiris, M and Webster, RG (2004). Reemerging H5N1 influenza viruses in Hong Kong in 2002 are highly pathogenic to ducks. Journal of Virology 78: 48924901.
Suarez, DL (2000). Evolution of avian influenza viruses. Veterinary Microbiology 74: 1527.
Suarez, DL (2008). Influenza A virus. In: Swayne, DE (ed.) Avian Influenza. Ames, IA: Blackwell Publishing, pp. 322.
Suarez, DL, Garcia, M, Latimer, J, Senne, D and Perdue, M (1999). Phylogenetic analysis of H7 avian influenza viruses isolated from the live bird markets of the Northeast United States. Journal of Virology 73: 35673573.
Suarez, DL, Perdue, ML, Cox, N, Rowe, T, Bender, C, Huang, J and Swayne, DE (1998). Comparisons of highly virulent H5N1 influenza A viruses isolated from humans and chickens from Hong Kong. Journal of Virology 72: 66786688.
Suarez, DL, Senne, DA, Banks, J, Brown, IH, Essen, SC, Lee, CW, Manvell, RJ, Mathieu-Benson, C, Moreno, V, Pedersen, JC, Panigrahy, B, Rojas, H, Spackman, E and Alexander, DJ (2004). Recombination resulting in virulence shift in avian influenza outbreak, Chile. Emerging Infectious Diseases 10: 693699.
Subbarao, EK, London, W and Murphy, BR (1993). A single amino acid in the PB2 gene of influenza A virus is a determinant of host range. Journal of Virology 67: 17611764.
Subbarao, K, Chen, H, Swayne, D, Mingay, L, Fodor, E, Brownlee, G, Xu, X, Lu, X, Katz, J, Cox, N and Matsuoka, Y (2003). Evaluation of a genetically modified reassortant H5N1 influenza A virus vaccine candidate generated by plasmid-based reverse genetics. Virology 305: 192200.
Subbarao, K, Klimov, A, Katz, J, Regnery, H, Lim, W, Hall, H, Perdue, M, Swayne, D, Bender, C, Huang, J, Hemphill, M, Rowe, T, Shaw, M, Xu, X, Fukuda, K and Cox, N (1998). Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness. Science 279: 393396.
Sun, Y (1997). Avian influenza in China. Fourth International Symposium on Avian Influenza, Athens, GA, US Animal Health Association, pp. 4749.
Suzuki, Y (2005). Sialobiology of influenza: molecular mechanism of host range variation of influenza viruses. Biological and Pharmacological Bulletin 28: 399408.
Swayne, DE (2008a). Epidemiology of avian influenza in agricultural and other man-made systems. In: Swayne, DE (ed.) Avian Influenza. Ames, IA: Blackwell Publishing, pp. 5985.
Swayne, DE (2008b). The global nature of avian influenza. In: Swayne, DE (ed) Avian Influenza. Ames, IA: Blackwell Publishing, pp. 123143.
Swayne, DE and Beck, JR (2005). Experimental study to determine if low-pathogenicity and high-pathogenicity avian influenza viruses can be present in chicken breast and thigh meat following intranasal virus inoculation. Avian Diseases 49: 8185.
Swayne, DE and Suarez, DL (2005). U.S. Strategies for Controlling Avian Influenza in Agricultural Systems. Washington, DC: National Academies Press.
Swayne, DE and Slemons, RD (2008). Using mean infectious dose of high- and low-pathogenicity avian influenza viruses originating from wild duck and poultry as one measure of infectivity and adaptation to poultry. Avian Diseases 52: 455460.
Swayne, DE, Senne, DA and Beard, CW (2008). Avian influenza. In: Dufour-Zavala, L (ed.) A Laboratory Manual for the Isolation, Identification, and Characterization of Avian Pathogens. 5th edn.Jacksonville, FL: American Association of Avian Pathologists. pp. 128134.
Swayne, DE, Beck, JR, Perdue, ML, Brugh, M and Slemons, RD (1996). Assessment of the ability of ratite-origin influenza viruses to infect and produce disease in rheas and chickens. Avian Diseases 40: 438447.
Tran, TH, Nguyen, TL, Nguyen, TD, Luong, TS, Pham, PM, Nguyen, VC, Pham, TS, Vo, CD, Le, TQ, Ngo, TT, Dao, BK, Le, PP, Nguyen, TT, Hoang, TL, Cao, VT, Le, TG, Nguyen, DT, Le, HN, Nguyen, KT, Le, HS, Le, VT, Christiane, D, Tran, TT, Menno de, J, Schultsz, C, Cheng, P, Lim, W, Horby, P, Farrar, J; World Health Organization International Avian Influenza Investigative Team (2004). Avian influenza A (H5N1) in 10 patients in Vietnam. New England Journal of Medicine 350: 11791188.
Tsukamoto, K, Imada, T, Tanimura, N, Okamatsu, M, Mase, M, Mizuhara, T, Swayne, D and Yamaguchi, S (2007). Impact of different husbandry conditions on contact and airborne transmission of H5N1 highly pathogenic avian influenza virus to chickens. Avian Diseases 51: 129132.
Tumpey, TM, Kapczynski, DR and Swayne, DE (2004). Comparative susceptibility of chickens and turkeys to avian influenza A H7N2 virus infection and protective efficacy of a commercial avian influenza H7N2 virus vaccine. Avian Diseases 48: 167176.
Tumpey, TM, Suarez, DL, Perkins, LE, Senne, DA, Lee, JG, Lee, YJ, Mo, IP, Sung, HW and Swayne, DE (2002). Characterization of a highly pathogenic H5N1 avian influenza A virus isolated from duck meat. Journal of Virology 76: 63446355.
van der Goot, JA, de Jong, MC, Koch, G and Van Boven, M (2003). Comparison of the transmission characteristics of low and high pathogenicity avian influenza A virus (H5N2). Epidemiology and Infection 131: 10031013.
van der Goot, JA, Koch, G, de Jong, MC and van Boven, M (2005). Quantification of the effect of vaccination on transmission of avian influenza (H7N7) in chickens. Proceedings of the National Academy of Sciences, USA 102: 1814118146.
Wallace, RG and Fitch, WM (2008). Influenza A H5N1 immigration is filtered out at some international borders. PLoS One 3: e1697.
Wan, H and Perez, DR (2006). Quail carry sialic acid receptors compatible with binding of avian and human influenza viruses. Virology 346: 278286.
Wang, J, Vijaykrishna, D, Duan, L, Bahl, J, Zhang, JX, Webster, RG, Peiris, JS, Chen, H, Smith, GJ and Guan, Y (2008). Identification of the progenitors of Indonesia and Vietnam avian influenza A (H5N1) viruses from southern China. Journal of Virology 82: 34053414.
Webster, RG, Guan, Y, Peiris, M, Walker, D, Krauss, S, Zhou, NN, Govorkova, EA, Ellis, TM, Dyrting, KC, Sit, T, Perez, DR and Shortridge, KF (2002). Characterization of H5N1 influenza viruses that continue to circulate in geese in southeastern China. Journal of Virology 76: 118126.
Werner, O, Starick, E, Teifke, J, Klopfleisch, R, Prajitno, TY, Beer, M, Hoffmann, B and Harder, TC (2007). Minute excretion of highly pathogenic avian influenza virus A/chicken/Indonesia/2003 (H5N1) from experimentally infected domestic pigeons (Columbia livia) and lack of transmission to sentinel chickens. Journal of General Virology 88: 30893093.
World Health Organization Global Influenza Program Surveillance Network (2005). Evolution of H5N1 avian influenza viruses in Asia. Emerging Infectious Diseases 11: 15151521.
World Organization for Animal Health (2006). Avian Influenza 2.7.12. Terrestrial Animal Health Code-2006, World Organization for Animal Health (Office International Epizooties).
Xu, X, Subbarao, K, Cox, NJ and Guo, Y (1999). Genetic characterization of the pathogenic influenza A/Goose/Guangdong/1/96 (H5N1) virus: similarity of its hemagglutinin gene to those of H5N1 viruses from the 1997 outbreaks in Hong Kong. Virology 261: 1519.
Yee, KS, Carpenter, TE, Farver, TB and Cardona, CJ (2009). An evaluation of transmission routes for low pathogenicity avian influenza virus among chickens sold in live bird markets. Virology 394: 1927.
Zhang, G, Shoham, D, Gilichinsky, D, Davydov, S, Castello, JD and Rogers, SO (2006). Evidence of influenza a virus RNA in Siberian lake ice. Journal of Virology 80: 1222912235.
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Animal Health Research Reviews
  • ISSN: 1466-2523
  • EISSN: 1475-2654
  • URL: /core/journals/animal-health-research-reviews
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