This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.
CL Adam and PA Findlay 2010. Decreased blood-brain leptin transfer in an ovine model of obesity and weight loss: resolving the cause of leptin resistance. International Journal of Obesity 34, 980–988.
CL Adam , PA Findlay and DW Miller 2006. Blood-brain leptin transport and appetite and reproductive neuroendocrine responses to intracerebroventricular leptin injection in sheep: influence of photoperiod. Endocrinology 147, 4589–4598.
RS Ahima and JS Flier 2000. Leptin. Annual Review of Physiology 62, 413–437.
RS Ahima , D Prabakaran , C Mantzoros , D Qu , B Lowell , E Maratos-Flier and JS Flier 1996. Role of leptin in the neuroendocrine response to fasting. Nature 382, 250–252.
DE Bauman and BW Currie
1980. Partitioning of nutrients during pregnancy and lactation: a review of mechanisms involving homeostasis and homeorhesis. Journal of Dairy Science
A Bell and D Bauman 1997. Adaptations of glucose metabolism during pregnancy and lactation. Journal of Mammary Gland Biology and Neoplasia 2, 265–278.
AW Bell 1995. Regulation of organic nutrient metabolism during transition from late pregnancy to early lactation. Journal of Animal Science 73, 2804–2819.
D Blache , R Tellam , L Chagas , M Blackberry , P Vercoe and G Martin
2000. Level of nutrition affects leptin concentrations in plasma and cerebrospinal fluid in sheep. Journal of Endocrinology
S Block , W Butler , R Ehrhardt , A Bell , M Van Amburgh and Y Boisclair 2001. Decreased concentration of plasma leptin in periparturient dairy cows is caused by negative energy balance. Journal of Endocrinology 171, 339–348.
N Chinookoswong , JL Wang and ZQ Shi
1999. Leptin restores euglycemia and normalizes glucose turnover in insulin-deficient diabetes in the rat. Diabetes
R Ehrhardt , R Slepetis , J Siegal-Willott , M Van Amburgh , A Bell and Y Boisclair 2000. Development of a specific radioimmunoassay to measure physiological changes of circulating leptin in cattle and sheep. Journal of Endocrinology 166, 519–528.
CAN Evans , JM Reynolds , ML Reynolds , NR Saunders and MB Segal 1974. The development of a blood-brain barrier mechanism in foetal sheep. The Journal of Physiology 238, 371–386.
IS Farooqi , S O'Rahilly 2009. Leptin: a pivotal regulator of human energy homeostasis. The American Journal of Clinical Nutrition 89, 980S–984S.
IS Farooqi , G Matarese , GM Lord , JM Keogh , E Lawrence , C Agwu , V Sanna , SA Jebb , F Perna , S Fontana , RI Lechler , AM DePaoli and S Rahilly
2002. Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. The Journal of Clinical Investigation
BA Henry , JW Goding , AJ Tilbrook , FR Dunshea , D Blache and IJ Clarke 2004. Leptin-mediated effects of undernutrition or fasting on luteinizing hormone and growth hormone secretion in ovariectomized ewes depend on the duration of metabolic perturbation. Journal of Neuroendocrinology 16, 244–255.
BA Henry , JW Goding , WS Alexander , AJ Tilbrook , BJ Canny , F Dunshea , A Rao , A Mansell and IJ Clarke 1999. Central administration of leptin to ovariectomized ewes inhibits food intake without affecting the secretion of hormones from the pituitary gland: evidence for a dissociation of effects on appetite and neuroendocrine function. Endocrinology 140, 1175–1182.
S Hidaka , H Yoshimatsu , S Kondou , Y Tsuruta , K Oka , H Noguchi , K Okamoto , H Sakino , Y Teshima , T Okeda and T Sakata
2002. Chronic central leptin infusion restores hyperglycemia independent of food intake and insulin level in streptozotocin-induced diabetic rats. The FASEB Journal
SM Hileman , KK Schillo and JB Hall 1993. Effects of acute, intracerebroventricular administration of insulin on serum concentrations of luteinizing hormone, insulin, and glucose in ovariectomized lambs during restricted and ad libitum feed intake. Biology of Reproduction 48, 117–124.
Q Huang , R Rivest and D Richard 1998. Effects of leptin on corticotropin-releasing factor (CRF) synthesis and CRF neuron activation in the paraventricular hypothalamic nucleus of obese (ob/ob) mice. Endocrinology 139, 1524–1532.
KL Ingvartsen and YR Boisclair 2001. Leptin and the regulation of food intake, energy homeostasis and immunity with special focus on periparturient ruminants. Domestic Animal Endocrinology 21, 215–250.
RL Leibel 2008. Molecular physiology of weight regulation in mice and humans. International Journal of Obesity 32, S98–S108.
C-Y Lin , DA Higginbotham , RL Judd and BD White 2002. Central leptin increases insulin sensitivity in streptozotocin-induced diabetic rats. American Journal of Physiology – Endocrinology and Metabolism 282, E1084–E1091.
C Morrison , J Daniel , B Holmberg , J Djiane , N Raver , A Gertler and D Keisler 2001. Central infusion of leptin into well-fed and undernourished ewe lambs: effects on feed intake and serum concentrations of growth hormone and luteinizing hormone. Journal of Endocrinology 168, 317–324.
CD Morrison , R Wood , EL McFadin , NC Whitley and DH Keisler 2002. Effect of intravenous infusion of recombinant ovine leptin on feed intake and serum concentrations of GH, LH, insulin, IGF-1, cortisol, and thyroxine in growing prepubertal ewe lambs. Domestic Animal Endocrinology 22, 103–112.
R Mullur , YY Liu and GA Brent
2014. Thyroid hormone regulation of metabolism. Physiological Reviews
MG Myers and DP Olson 2012. Central nervous system control of metabolism. Nature 491, 357–363.
L Niv-Spector , D Gonen-Berger , I Gourdou , E Biener , EE Gussakovsky , Y Benomar , KV Ramanujan , M Taouis , B Herman , I Callebaut , J Djiane and A Gertler 2005. Identification of the hydrophobic strand in the A-B loop of leptin as major binding site III: implications for large-scale preparation of potent recombinant human and ovine leptin antagonists. Biochemical Journal 391, 221–230.
G Paz-Filho , ML Wong and J Licinio 2011. Ten years of leptin replacement therapy. Obesity Reviews 12, E315–E323.
RJ Perry , X-M Zhang , D Zhang , N Kumashiro , J-PG Camporez , GW Cline , DL Rothman and GI Shulman 2014. Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis. Natural Medicine 20, 759–763.
M Reist , D Erdin , D von Euw , K Tschuemperlin , H Leuenberger , C Delavaud , Y Chilliard , HM Hammon , N Kuenzi and JW Blum 2003. Concentrate feeding strategy in lactating dairy cows: metabolic and endocrine changes with emphasis on leptin. Journal of Dairy Science 86, 1690–1706.
M Rosenbaum , R Goldsmith , D Bloomfield , A Magnano , L Weimer , S Heymsfield , D Gallagher , L Mayer , E Murphy and RL Leibel 2005. Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight. The Journal of Clinical Investigation 115, 3579–3586.
1984. Body condition scoring of sheep. In Practice
RA Shipley and ER Clark 1972. Tracer methods for in vivo kinetics: theory and applications. Academic Press Inc., New York, NY.
SR Thorn , RA Ehrhardt , WR Butler , SM Quirk and YR Boisclair 2008. Insulin regulates hepatic leptin receptor expression in early lactating dairy cows. American Journal of Physiology – Regulatory, Integrative and Comparative Physiology 295, R1455–R1462.
J Zhang , MK Matheny , N Tumer , MK Mitchell and PJ Scarpace
2007. Leptin antagonist reveals that the normalization of caloric intake and the thermic effect of food after high-fat feeding are leptin dependent. American Journal of Physiology – Regulatory, Integrative and Comparative Physiology