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Bulking up the hippocampus in schizophrenia: a role for 5-HT1A agonists?

  • Sophia Frangou (a1)
Summary

The volume of the hippocampus is reduced in patients with schizophrenia, and this deficit tends to become more pronounced with chronicity. Newer antipsychotics may protect against the progressive reductions in hippocampal volume while preliminary data offer hope that specific antipsychotics may act to reverse it.

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Copyright
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Corresponding author
Sophia Frangou, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY 10029, USA. Email: sophia.frangou@mssm.edu
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Declaration of interest

None.

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References
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BJPsych Open
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Bulking up the hippocampus in schizophrenia: a role for 5-HT1A agonists?

  • Sophia Frangou (a1)
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