Hoskins, M, Pearce, J, Bethell, A, Dankova, L, Barbui, C, Tol, WA, et al. Pharmacotherapy for post-traumatic stress disorder: systematic review and metaanalysis. Br J Psychiatry
2015; 206: 93–100.
Jonas, DE, Cusack, K, Forneris, CA, Wilkins, TM, Sonis, J, Middleton, JC, et al. Psychological and Pharmacological Treatments for Adults with Posttraumatic Stress Disorder (PTSD). Agency for Healthcare Research and Quality, Rockville (MD), 2013.
Tanielian, TL, Jaycox, L, RAND Corporation. Invisible Wounds of War: Psychological and Cognitive Injuries, Their Consequences, and Services to Assist Recovery. RAND Corporation, 2008.
Harpaz-Rotem, I, Rosenheck, RA. Serving those who served: retention of newly returning veterans from Iraq and Afghanistan in mental health treatment. Psychiatr Serv
2011; 62: 22–7.
Hoge, CW, Castro, CA, Messer, SC, McGurk, D, Cotting, DI, Koffman, RL. Combat duty in Iraq and Afghanistan, mental health problems, and barriers to care. N Engl J Med
2004; 351: 13–22.
Hoge, CW, Auchterlonie, JL, Milliken, CS. Mental health problems, use of mental health services, and attrition from military service after returning from deployment to Iraq or Afghanistan. JAMA
2006; 295: 1023–32.
Milliken, CS, Auchterlonie, JL, Hoge, CW. Longitudinal assessment of mental health problems among active and reserve component soldiers returning from the Iraq war. JAMA
2007; 298: 2141–8.
Seal, KH, Bertenthal, D, Miner, CR, Sen, S, Marmar, C. Bringing the war back home: mental health disorders among 103,788 US veterans returning from Iraq and Afghanistan seen at Department of Veterans Affairs facilities. Arch Intern Med
2007; 167: 476–82.
Mohamed, S, Rosenheck, RA. Pharmacotherapy of PTSD in the U.S. Department of Veterans Affairs: diagnostic- and symptom-guided drug selection. J Clin Psychiatry
2008; 69: 959–65.
Harpaz-Rotem, I, Rosenheck, RA, Mohamed, S, Desai, RA. Pharmacologic treatment of posttraumatic stress disorder among privately insured Americans. Psychiatr Serv
2008; 59: 1184–90.
Management of Post-Traumatic Stress Working Group. VA/DoD Clinical Practice Guideline: Management of Post-Traumatic Stress, 2010: Guideline Summary. US Department of Veterans Affairs and the Department of Defense, 2010.
National Institute for Clinical Excellence. Post-Traumatic Stress Disorder: The Management of PTSD in Adults and Children in Primary and Secondary Care. The Royal College of Psychiatrists & The British Psychological Society, 2005.
Forbes, D, Creamer, M, Phelps, A, Bryant, R, McFarlane, A, Devilly, GJ, et al. Australian guidelines for the treatment of adults with acute stress disorder and post-traumatic stress disorder. Aust N Z J Psychiatry
2007; 41: 637–48.
Stein, DJ, Ipser, JC, Seedat, S. Pharmacotherapy for Post traumatic Stress Disorder (PTSD). The Cochrane Library, 2006.
Hamner, MB, Faldowski, RA, Ulmer, HG, Frueh, BC, Huber, MG, Arana, GW. Adjunctive risperidone treatment in post-traumatic stress disorder: a preliminary controlled trial of effects on comorbid psychotic symptoms. Int Clin Psychopharmacol
2003; 18: 1–8.
Carey, P, Suliman, S, Ganesan, K, Seedat, S, Stein, DJ. Olanzapine monotherapy in posttraumatic stress disorder: efficacy in a randomized, double-blind, placebo-controlled study. Hum Psychopharmacol
2012; 27: 386–91.
Krystal, JH, Rosenheck, RA, Cramer, JA, Vessicchio, JC, Jones, KM, Vertrees, JE, et al. Adjunctive risperidone treatment for antidepressant-resistant symptoms of chronic military service-related PTSD: a randomized trial. JAMA
2011; 306: 493–502.
Villarreal, G, Hamner, MB, Canive, JM, Robert, S, Calais, LA, Durklaski, V, et al. Efficacy of quetiapine monotherapy in posttraumatic stress disorder: a randomized, placebo-controlled trial. Am J Psychiatry
Leslie, DL, Mohamed, S, Rosenheck, RA. Off-label use of antipsychotic medications in the Department of Veterans Affairs health care system. Psychiatr Serv
2009; 60: 1175–81.
Lund, BC, Bernardy, NC, Vaughan-Sarrazin, M, Alexander, B, Friedman, MJ. Patient and facility characteristics associated with benzodiazepine prescribing for veterans with PTSD. Psychiatr Serv
2013; 64: 149–55.
Lader, M, Tylee, A, Donoghue, J. Withdrawing benzodiazepines in primary care. CNS Drugs
2009; 23: 19–34.
Rosen, CS, Greenbaum, MA, Schnurr, PP, Holmes, TH, Brennan, PL, Friedman, MJ. Do benzodiazepines reduce the effectiveness of exposure therapy for posttraumatic stress disorder?
J Clin Psychiatry
2013; 74: 1241–8.
Raskind, MA, Peskind, ER, Hoff, DJ, Hart, KL, Holmes, HA, Warren, D, et al. A parallel group placebo controlled study of prazosin for trauma nightmares and sleep disturbance in combat veterans with post-traumatic stress disorder. Biol Psychiatry
2007; 61: 928–34.
Raskind, MA, Peskind, ER, Kanter, ED, Petrie, EC, Radant, A, Thompson, CE, et al. Reduction of nightmares and other PTSD symptoms in combat veterans by prazosin: a placebo-controlled study. Am J Psychiatry
2003; 160: 371–3.
Raskind, MA, Peterson, K, Williams, T, Hoff, DJ, Hart, K, Holmes, H, et al. A trial of prazosin for combat trauma PTSD with nightmares in active-duty soldiers returned from Iraq and Afghanistan. Am J Psychiatry
2013; 170: 1003–10.
Raskind, MA, Thompson, C, Petrie, EC, Dobie, DJ, Rein, RJ, Hoff, DJ, et al. Prazosin reduces nightmares in combat veterans with posttraumatic stress disorder. J Clin Psychiatry
2002; 63: 565–8.
Taylor, FB, Lowe, K, Thompson, C, McFall, MM, Peskind, ER, Kanter, ED, et al. Daytime prazosin reduces psychological distress to trauma specific cues in civilian trauma posttraumatic stress disorder. Biol Psychiatry
2006; 59: 577–81.
Taylor, FB, Martin, P, Thompson, C, Williams, J, Mellman, TA, Gross, C, et al. Prazosin effects on objective sleep measures and clinical symptoms in civilian trauma posttraumatic stress disorder: a placebo-controlled study. Biol Psychiatry
2008; 63: 629–32.
Harpaz-Rotem, I, Rosenheck, RA. Tracing the flow of knowledge: geographic variability in the diffusion of prazosin use for the treatment of posttraumatic stress disorder nationally in the Department of Veterans Affairs. Arch Gen Psychiatry
2009; 66: 417–21.
Hermes, E, Harpaz-Rotem, I, Rosenheck, R. Diffusion of prazosin treatment for PTSD. Am J Psychiatry
2014; 171: 117.
Davidson, J. Vintage treatments for PTSD: a reconsideration of tricyclic drugs. J Psychopharmacol
2015; 29: 264–9.
Weathers, F, Huska, J, Keane, TM. The PTSD Checklist-Military Version (PCL-M). The National Center for Posttraumatic Stress Disorder, 1991.
Harpaz-Rotem, I, Rosenheck, RA, Pietrzak, RH, Southwick, SM. Determinants of prospective engagement in mental health treatment among symptomatic Iraq/Afghanistan veterans. J Nerv Ment Dis
2014; 202: 97–104.
Harpaz-Rotem, I, Tsai, J, Pietrzak, RH, Hoff, R. The dimensional structure of posttraumatic stress symptomatology in 323,903 U.S. veterans. J Psychiatr Res
2013; 49: 31–6.
Shevlin, M, McBride, O, Armour, C, Adamson, G. Reconciling the differences between the King et al. (1998) and Simms et al. (2002) factor models of PTSD. J Anxiety Disord
2009; 23: 995–1001.
Pietrzak, RH, Tsai, J, Harpaz-Rotem, I, Whealin, JM, Southwick, SM. Support for a novel five-factor model of posttraumatic stress symptoms in three independent samples of Iraq/Afghanistan veterans: a confirmatory factor analytic study. J Psychiatr Res
2012; 46: 317–22.
Insel, T, Cuthbert, B, Garvey, M, Heinssen, R, Pine, DS, Quinn, K, et al. Research domain criteria (RDoC): toward a new classification framework for research on mental disorders. Am J Psychiatry
2010; 167: 748–51.
Gaudiano, BA, Zimmerman, M. Evaluation of evidence for the psychotic subtyping of post-traumatic stress disorder. Br J Psychiatry
2010; 197: 326–7.
Seida, JC, Schouten, JR, Mousavi, SS, Hamm, M, Beaith, A, Vandermeer, B, et al. AHRQ Comparative Effectiveness Reviews. First- and Second-Generation Antipsychotics for Children and Young Adults. Agency for Healthcare Research and Quality (US), 2012.