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The acute effect of D-tagatose on food intake in human subjects

Published online by Cambridge University Press:  09 March 2007

Benjamin Buemann*
Affiliation:
Research Department of Human Nutrition & Centre for Food Research, The Royal Veterinary and Agricultural University, 1958 Frederiksberg, Denmark
Søren Toubro
Affiliation:
Research Department of Human Nutrition & Centre for Food Research, The Royal Veterinary and Agricultural University, 1958 Frederiksberg, Denmark
Anne Raben
Affiliation:
Research Department of Human Nutrition & Centre for Food Research, The Royal Veterinary and Agricultural University, 1958 Frederiksberg, Denmark
John Blundell
Affiliation:
Research Department of Human Nutrition & Centre for Food Research, The Royal Veterinary and Agricultural University, 1958 Frederiksberg, Denmark
Arne Astrup
Affiliation:
Research Department of Human Nutrition & Centre for Food Research, The Royal Veterinary and Agricultural University, 1958 Frederiksberg, Denmark
*
*Corresponding author: Dr Benjamin Buemann, fax +45 35 282 483, email bbu@kvl.dk
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Abstract

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A double-blind randomized crossover study was performed with nineteen normal-weight men to investigate the effect on subsequent ad libitum food intake of replacing 29 g sucrose with 29 g D-TAGATOSE AS SWEETENER TO A BREAKFAST MEAL. d-Tagatose is a malabsorbed stereoisomer of fructose with potential application as a bulk sweetener. Food intake was measured at lunch offered 4 h after the breakfast meal, during the afternoon with access to abundant snacks, and finally at a supper buffet 9 h after the breakfast. Energy intake at lunch and during the snacking period was similar after ingesting the two sugars, while it was 15 % lower after ingesting d-tagatose than with sucrose at supper (P < 0·05). Gastrointestinal factors such as the osmotic effects of unabsorbed d-tagatose causing distension of the gut might have mediated the acute appetite-suppressing effect. The present paper also refers to data from a preceding study in which we observed an increased self-reported energy intake after ingestion of d-tagatose compared with sucrose which, in fact, suggests a relative hyperphagic effect of d-tagatose. However, self-reported food intake may be biased by selective under-reporting and this subsequent study with a more controlled assessment of food intake was therefore conducted. This present study did not support any hyperphagic effect of d-tagatose, but rather suggests that d-tagatose may contribute to a reduced energy intake.

Type
Research Article
Copyright
Copyright © The Nutrition Society 2000

References

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