Skip to main content
×
Home
    • Aa
    • Aa
  • Access
  • Cited by 15
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Cetin, Ihsan Nalbantcilar, Mahmut Tahir Tosun, Kezban and Nazik, Aydan 2016. How Trace Element Levels of Public Drinking Water Affect Body Composition in Turkey. Biological Trace Element Research,


    Hutchinson, Carol 2016. A review of iron studies in overweight and obese children and adolescents: a double burden in the young?. European Journal of Nutrition,


    2016. TEMPORARY REMOVAL: Canadian Consensus on Female Nutrition: Adolescence, Reproduction, Menopause, and Beyond. Journal of Obstetrics and Gynaecology Canada, Vol. 38, Issue. 6, p. 508.


    2016. TEMPORARY REMOVAL: Consensus canadien sur la nutrition féminine : adolescence, reproduction, ménopause et au-delà. Journal of Obstetrics and Gynaecology Canada, Vol. 38, Issue. 6, p. 555.


    Choma, Solomon Simon Ramphai Alberts, Marianne and Modjadji, Sewela Elizabeth Perpetua 2015. Conflicting effects of BMI and waist circumference on iron status. Journal of Trace Elements in Medicine and Biology, Vol. 32, p. 73.


    Feldman, Alexandra Aigner, Elmar Weghuber, Daniel and Paulmichl, Katharina 2015. The Potential Role of Iron and Copper in Pediatric Obesity and Nonalcoholic Fatty Liver Disease. BioMed Research International, Vol. 2015, p. 1.


    Ferrari, M Cuenca-García, M Valtueña, J Moreno, L A Censi, L González-Gross, M Androutsos, O Gilbert, C C Huybrechts, I Dallongeville, J Sjöström, M Molnar, D De Henauw, S Gómez-Martínez, S de Moraes, A C F Kafatos, A Widhalm, K and Leclercq, C 2015. Inflammation profile in overweight/obese adolescents in Europe: an analysis in relation to iron status. European Journal of Clinical Nutrition, Vol. 69, Issue. 2, p. 247.


    Wendt, Amanda S Jefferds, Maria E Perrine, Cria G Halleslevens, Patricia and Sullivan, Kevin M 2015. Obese women less likely to have low serum ferritin, Nicaragua. Public Health Nutrition, Vol. 18, Issue. 04, p. 736.


    Zhao, L. Zhang, X. Shen, Y. Fang, X. Wang, Y. and Wang, F. 2015. Obesity and iron deficiency: a quantitative meta-analysis. Obesity Reviews, Vol. 16, Issue. 12, p. 1081.


    Abd-El Wahed, Mohamed A. Mohamed, Maha H. Ibrahim, Samia S. and El-Naggar, Wafaa A. 2014. Iron profile and dietary pattern of primary school obese Egyptian children. Journal of the Egyptian Public Health Association, Vol. 89, Issue. 2, p. 53.


    Androutsos, Odysseas Moschonis, George Koumpitski, Alexandra Mantzou, Aimilia Roma-Giannikou, Eleftheria Chrousos, George P. Manios, Yannis and Kanaka-Gantenbein, Christina 2014. The correlation of right 2D:4D finger length ratio to the low-grade inflammation marker IL-6 in children. The Healthy Growth Study. Early Human Development, Vol. 90, Issue. 1, p. 61.


    Androutsos, O Moschonis, G Mavrogianni, C Roma-Giannikou, E Chrousos, G P Kanaka-Gantenbein, C and Manios, Y 2014. Identification of lifestyle patterns, including sleep deprivation, associated with insulin resistance in children: the Healthy Growth Study. European Journal of Clinical Nutrition, Vol. 68, Issue. 3, p. 344.


    Bouglé, Dominique and Brouard, Jacques 2013. Iron in Child Obesity. Relationships with Inflammation and Metabolic Risk Factors. Nutrients, Vol. 5, Issue. 6, p. 2222.


    Moschonis, George Papandreou, Dimitrios Mavrogianni, Christina Giannopoulou, Angeliki Damianidi, Louisa Malindretos, Pavlos Lionis, Christos Chrousos, George P. and Manios, Yannis 2013. Association of Iron Depletion with Menstruation and Dietary Intake Indices in Pubertal Girls: The Healthy Growth Study. BioMed Research International, Vol. 2013, p. 1.


    Androutsos, O. Grammatikaki, E. Moschonis, G. Roma-Giannikou, E. Chrousos, G. P. Manios, Y. and Kanaka-Gantenbein, C. 2012. Neck circumference: a useful screening tool of cardiovascular risk in children. Pediatric Obesity, Vol. 7, Issue. 3, p. 187.


    ×

Association of total body and visceral fat mass with iron deficiency in preadolescents: the Healthy Growth Study

  • George Moschonis (a1), George P. Chrousos (a2), Christos Lionis (a3), Vassilis Mougios (a4) and Yannis Manios (a1)
  • DOI: http://dx.doi.org/10.1017/S0007114511005952
  • Published online: 16 November 2011
Abstract

The aim of the present study was to examine the associations of obesity, percentage body fat and visceral fat mass with body Fe status in a representative sample of 1493 schoolchildren aged 9–13 years. Anthropometric, body composition, biochemical, clinical (Tanner stage, age of menarche) and dietary intake data were collected. Fe deficiency (ID) was defined as transferrin saturation (TS) < 16 %; and Fe-deficiency anaemia (IDA) as ID with Hb < 120 g/l. Obese boys and girls and those in the highest quartiles of percentage body fat mass had significantly higher levels of serum ferritin (P ≤ 0·05) compared to their normal-weight peers and those in the corresponding lowest quartiles. Similarly, obese boys and girls and those in the highest quartiles of percentage body fat and visceral fat mass had significantly lower levels of TS (P ≤ 0·05) compared to normal-weight children and those in the corresponding lowest quartiles. The prevalence of ID and IDA was significantly higher in boys and girls in the highest quartiles of percentage body fat than in peers in the lowest quartile. Higher quartiles of percentage body fat and visceral fat mass were the main significant predictors of ID in boys, after controlling for other important confounders, with OR of 2·48 (95 % CI, 1·26, 4·88) and 2·12 (95 % CI, 1·07, 4·19), respectively. Similar significant associations were observed for girls. In conclusion, percentage body fat and visceral fat mass were positively associated with ID in both sexes of preadolescents. These associations might be attributed to the chronic inflammation induced by excess adiposity.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Association of total body and visceral fat mass with iron deficiency in preadolescents: the Healthy Growth Study
      Your Kindle email address
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      Association of total body and visceral fat mass with iron deficiency in preadolescents: the Healthy Growth Study
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      Association of total body and visceral fat mass with iron deficiency in preadolescents: the Healthy Growth Study
      Available formats
      ×
Copyright
Corresponding author
*Corresponding author: Dr Y. Manios, fax +30 210 9514759, email manios@hua.gr
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1A Cattaneo , L Monasta , E Stamatakis , (2010) Overweight and obesity in infants and pre-school children in the European Union: a review of existing data. Obes Rev 11, 389398.

2CL Ogden , MD Carroll , LR Curtin , (2009) Prevalence of high body mass index in US children and adolescents, 2007–2008. JAMA 303, 242249.

3Y Wang & T Lobstein (2006) Worldwide trends in childhood overweight and obesity. Int J Pediatr Obes 1, 1125.

4Y Manios , F Magkos , G Christakis , (2005) Twenty-year dynamics in adiposity and blood lipids of Greek children: regional differences in Crete persist. Acta Paediatr 94, 859865.

8O Kaidar-Person , B Person , S Szomstein , (2008) Nutritional deficiencies in morbidly obese patients: a new form of malnutrition? Obes Surg 18, 870876.

10LM Tussing-Humphreys , E Nemeth , G Fantuzzi , (2010) Elevated systemic hepcidin and iron depletion in obese premenopausal females. Obesity (Silver Spring) 18, 14491456.

11JM Brotanek , J Gosz , M Weitzman , (2007) Iron deficiency in early childhood in the United States: risk factors and racial/ethnic disparities. Pediatrics 120, 568575.

12KG Nead , JS Halterman , JM Kaczorowski , (2004) Overweight children and adolescents: a risk group for iron deficiency. Pediatrics 114, 104108.

13A Amato , N Santoro , P Calabro , (2010) Effect of body mass index reduction on serum hepcidin levels and iron status in obese children. Int J Obes (Lond) 34, 17721774.

14O Pinhas-Hamiel , RS Newfield , I Koren , (2003) Greater prevalence of iron deficiency in overweight and obese children and adolescents. Int J Obes Relat Metab Disord 27, 416418.

15AC Cepeda-Lopez , I Aeberli & MB Zimmermann (2010) Does obesity increase risk for iron deficiency? A review of the literature and the potential mechanisms. Int J Vitam Nutr Res 80, 263270.

16CM Menzie , LB Yanoff , BI Denkinger , (2008) Obesity-related hypoferremia is not explained by differences in reported intake of heme and nonheme iron or intake of dietary factors that can affect iron absorption. J Am Diet Assoc 108, 145148.

17A Lecube , A Carrera , E Losada , (2006) Iron deficiency in obese postmenopausal women. Obesity (Silver Spring) 14, 17241730.

19JS Halterman , JM Kaczorowski , CA Aligne , (2001) Iron deficiency and cognitive achievement among schoolaged children and adolescents in the United States. Pediatrics 107, 13811386.

20B Lozoff , E Jimenez & AW Wolf (1991) Long-term developmental outcomes of infants with iron deficiency. N Engl J Med 325, 687694.

22V Subramanian & AW Ferrante Jr (2009) Obesity, inflammation, and macrophages. Nestle Nutr Workshop Ser Pediatr Program 63, 151159, 259–168.

23T Iwasaki , A Nakajima , M Yoneda , (2005) Serum ferritin is associated with visceral fat area and subcutaneous fat area. Diabetes Care 28, 24862491.

25TJ Cole , KM Flegal , D Nicholls , (2007) Body mass index cut offs to define thinness in children and adolescents: international survey. BMJ 335, 194.

26TJ Cole , MC Bellizzi , KM Flegal , (2000) Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 320, 12401243.

27JR Fernandez , DT Redden , A Pietrobelli , (2004) Waist circumference percentiles in nationally representative samples of African-American, European-American, and Mexican-American children and adolescents. J Pediatr 145, 439444.

29M Ryo , K Maeda , T Onda , (2005) A new simple method for the measurement of visceral fat accumulation by bioelectrical impedance. Diabetes Care 28, 451453.

30BM Nielsen , M Dencker , L Ward , (2007) Prediction of fat-free body mass from bioelectrical impedance among 9- to 11-year-old Swedish children. Diabetes Obes Metab 9, 521539.

35BE Wisse (2004) The inflammatory syndrome: the role of adipose tissue cytokines in metabolic disorders linked to obesity. J Am Soc Nephrol 15, 27922800.

36RF Gillum (2001) Association of serum ferritin and indices of body fat distribution and obesity in Mexican American men – the Third National Health and Nutrition Examination Survey. Int J Obes Relat Metab Disord 25, 639645.

37CE Wrede , R Buettner , LC Bollheimer , (2006) Association between serum ferritin and the insulin resistance syndrome in a representative population. Eur J Endocrinol 154, 333340.

38M Hassapidou , E Fotiadou , E Maglara , (2006) Energy intake, diet composition, energy expenditure, and body fatness of adolescents in northern Greece. Obesity (Silver Spring) 14, 855862.

40LM Tussing-Humphreys , E Nemeth , G Fantuzzi , (2010) Decreased serum hepcidin and improved functional iron status 6 months after restrictive bariatric surgery. Obesity (Silver Spring) 18, 20102016.

41MV Verga Falzacappa , M Vujic Spasic & R Kessler (2007) STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation. Blood 109, 353358.

42C Zafon , A Lecube & R Simo (2009) Iron in obesity. An ancient micronutrient for a modern disease. Obes Rev 11, 322328.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords: