1Larsson SC & Wolk A (2006) Meat consumption and risk of colorectal cancer: a meta-analysis of prospective studies. Int J Cancer 119, 2657–2664.
2Norat T, Lukanova A, Ferrari P & Riboli E (2002) Meat consumption and colorectal cancer risk: dose-response meta-analysis of epidemiological studies. Int J Cancer 98, 241–256.
3Lee DH, Anderson KE, Harnack LJ, Folsom AR & Jacobs DR Jr (2004) Heme iron, zinc, alcohol consumption, and colon cancer: Iowa Women's Health Study. J Natl Cancer Inst 96, 403–407.
4Larsson SC, Rafter J, Holmberg L, Bergkvist L & Wolk A (2005) Red meat consumption and risk of cancers of the proximal colon, distal colon and rectum: the Swedish Mammography Cohort. Int J Cancer 113, 829–834.
5Sesink ALA, Termont DSML, Kleibeuker JH & Vandermeer R (1999) Red meat and colon cancer: the cytotoxic and hyperproliferative effects of dietary heme. Cancer Res 59, 5704–5709.
6Pierre F, Tache S, Petit CR, Van der Meer R & Corpet DE (2003) Meat and cancer: haemoglobin and haemin in a low-calcium diet promote colorectal carcinogenesis at the aberrant crypt stage in rats. Carcinogenesis 24, 1683–1690.
7Pierre F, Freeman A, Tache S, Van der Meer R & Corpet DE (2004) Beef meat and blood sausage promote the formation of azoxymethane-induced mucin-depleted foci and aberrant crypt foci in rat colons. J Nutr 134, 2711–2716.
8Pierre F, Peiro G, Tache S, Cross AJ, Bingham SA, Gasc N, Gottardi G, Corpet DE & Gueraud F (2006) New marker of colon cancer risk associated with heme intake: 1,4-dihydroxynonane mercapturic acid. Cancer Epidemiol Biomarkers Prev 15, 2274–2279.
9Sesink ALA, Termont DSML, Kleibeuker JH & VanDerMeer R (2001) Red meat and colon cancer: dietary haem-induced colonic cytotoxicity and epithelial hyperproliferation are inhibited by calcium. Carcinogenesis 22, 1653–1659.
10Karkare MR, Clark TD & Glauert HP (1991) Effect of dietary calcium on colon carcinogenesis induced by a single injection of 1,2-dimethylhydrazine in rats. J Nutr 121, 568–577.
11American Institute of Nutrition (1977) Report of the American Institute of Nutrition Ad Hoc Committee on standards for nutritional studies. J Nutr 107, 1340–1348.
12Bird RP (1987) Observation and quantification of aberrant crypts in murine colon treated with a colon carcinogen: preliminary findings. Cancer Lett 37, 147–151.
13Femia AP, Dolara P, Giannini A, Salvadori M, Biggeri A & Caderni G (2007) Frequent mutation of Apc gene in rat colon tumors and mucin-depleted foci, preneoplastic lesions in experimental colon carcinogenesis. Cancer Res 67, 445–449.
14Caderni G, Femia AP, Giannini A, Favuzza A, Luceri C, Salvadori M & Dolara P (2003) Identification of mucin-depleted foci in the unsectioned colon of azoxymethane-treated rats: correlation with carcinogenesis. Cancer Res 63, 2388–2392.
15Ohkawa H, Ohishi N & Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95, 351–358.
16Van den Berg JW, Koole-Lesuis R, Edixhoven-Bosdijk A & Brouwers N (1988) Automating the quantification of heme in feces. Clin Chem 34, 2125–2126.
17Bonneson C, Eggleston IM & Hayes JD (2001) Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines. Cancer Res 61, 6120–6130.
18Gueraud F, Peiro G, Bernard H, et al. (2006) Enzyme immunoassay for a urinary metabolite of 4-hydroxynonenal as a marker of lipid peroxidation. Free Radic Biol Med 40, 54–62.
19Bingham SA, Pignatelli B, Pollock JRA, Ellul A, Malaveille C, Gross G, Runswick S, Cummings JH & Oneill IK (1996) Does increased endogenous formation of N-nitroso compounds in the human colon explain the association between red meat and colon cancer? Carcinogenesis 17, 515–523.
20Lunn JC, Kuhnle G, Mai V, Frankenfeld C, Shuker DE, Glen RC, Goodman JM, Pollock JR & Bingham SA (2006) The effect of haem in red and processed meat on the endogenous formation of N-nitroso compounds in the upper gastrointestinal tract. Carcinogenesis 28, 685–690.
21Pierre F, Tache S, Gueraud F, Rerole AL, Jourdan ML & Petit C (2007) Apc mutation induces resistance of colonic cells to lipoperoxide-triggered apoptosis induced by faecal water from haem-fed rats. Carcinogenesis 28, 321–327.
22Yang LP, Mutanen M, Cheng YJ & Duan RD (2002) Effects of red meat and fiber in high fat diet on activities of sphingomyelinase, ceramidase and caspase-3 in rat colonic mucosa. J Nutr Biochem 13, 499–504.
23Huang X & Guo B (2006) Adenomatous polyposis coli determines sensitivity to histone deacetylase inhibitor-induced apoptosis in colon cancer cells. Cancer Res 66, 9245–9251.
24Zhu P, Martin E, Mengwasser J, Schlag P, Janssen KP & Gottlicher M (2004) Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis. Cancer Cell 5, 455–463.
25Rahman I, Marwick J & Kirkham P (2004) Redox modulation of chromatin remodeling: impact on histone acetylation and deacetylation, NF-kappaB and pro-inflammatory gene expression. Biochem Pharmacol 68, 1255–1267.
26Balder HF, Vogel J, Jansen MC, Weijenberg MP, van den Brandt PA, Westenbrink S, van der Meer R & Goldbohm RA (2006) Heme and chlorophyll intake and risk of colorectal cancer in the Netherlands cohort study. Cancer Epidemiol Biomarkers Prev 15, 717–725.
27Newmark HL & Lipkin M (1992) Calcium, vitamin-D, and colon cancer. Cancer Res 52, S2067–S2070.
28Corpet DE & Pierre F (2005) How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men. Eur J Cancer 41, 1911–1922.
29Weisburger JH, Braley J, Reinhardt J, Aliaga C, Rivenson A, Hard GC, Zhang XM, Takahashi M, Esumi H & Sugimura T (1994) The role of fat and calcium in the production of foci of aberrant crypts in the colon of rats fed 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Environ Health Perspect 102, 53–55.
30Bull A, Bird RP, Bruce WR, Nigro N & Medline A (1987) Effect of calcium on azoxymethane induced intestinal tumors in rats. Gastroenterology 92, 1332.
31Bruce WR, Giacca A & Medline A (2001) Possible mechanisms relating diet to colorectal cancer risk. In European Conference on Nutrition and Cancer, pp. 1–7, . Lyon, France: IARC Scientific Publications.
32Gasc N, Tache S, Rathahao E, Bertrand-Michel J, Roques V & Gueraud F (2007) 4-Hydroxynonenal in foodstuffs: heme concentration, fatty acid composition and freeze-drying are determining factors. Redox Rep 12, 40–44.
33Blei AT & Cordoba J (2001) Hepatic encephalopathy. Am J Gastroenterol 96, 1968–1976.