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    Yarnell, Eric and Abascal, Kathy 2014. Herbs for Diabetes: Update—Part 1. Alternative and Complementary Therapies, Vol. 20, Issue. 6, p. 328.


    Beejmohun, Vickram Peytavy-Izard, Marie Mignon, Cyril Muscente-Paque, Delphine Deplanque, Xavier Ripoll, Christophe and Chapal, Nicolas 2014. Acute effect of Ceylon cinnamon extract on postprandial glycemia: alpha-amylase inhibition, starch tolerance test in rats, and randomized crossover clinical trial in healthy volunteers. BMC Complementary and Alternative Medicine, Vol. 14, Issue. 1,


    Wickenberg, Jennie Lindstedt, Sandra Nilsson, Jan and Hlebowicz, Joanna 2014. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutrition Journal, Vol. 13, Issue. 1,


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Ceylon cinnamon does not affect postprandial plasma glucose or insulin in subjects with impaired glucose tolerance

  • Jennie Wickenberg (a1) (a2), Sandra Lindstedt (a3), Kerstin Berntorp (a4), Jan Nilsson (a1) (a2) and Joanna Hlebowicz (a1) (a2) (a5)
  • DOI: http://dx.doi.org/10.1017/S0007114511005113
  • Published online: 20 September 2011
Abstract

Previous studies on healthy subjects have shown that the intake of 6 g Cinnamomum cassia reduces postprandial glucose and that the intake of 3 g C. cassia reduces insulin response, without affecting postprandial glucose concentrations. Coumarin, which may damage the liver, is present in C. cassia, but not in Cinnamomum zeylanicum. The aim of the present study was to study the effect of C. zeylanicum on postprandial concentrations of plasma glucose, insulin, glycaemic index (GI) and insulinaemic index (GII) in subjects with impaired glucose tolerance (IGT). A total of ten subjects with IGT were assessed in a crossover trial. A standard 75 g oral glucose tolerance test (OGTT) was administered together with placebo or C. zeylanicum capsules. Finger-prick capillary blood samples were taken for glucose measurements and venous blood for insulin measurements, before and at 15, 30, 45, 60, 90, 120, 150 and 180 min after the start of the OGTT. The ingestion of 6 g C. zeylanicum had no significant effect on glucose level, insulin response, GI or GII. Ingestion of C. zeylanicum does not affect postprandial plasma glucose or insulin levels in human subjects. The Federal Institute for Risk Assessment in Europe has suggested the replacement of C. cassia by C. zeylanicum or the use of aqueous extracts of C. cassia to lower coumarin exposure. However, the positive effects seen with C. cassia in subjects with poor glycaemic control would then be lost.

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Corresponding author
*Corresponding author: J. Hlebowicz, fax +46 40 92 32 72, email joanna.hlebowicz@med.lu.se
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British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
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