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1PM Ueland (2011) Choline and betaine in health and disease. J Inherit Metab Dis 34, 3–15.
4JK Blusztajn , M Liscovitch & UI Richardson (1987) Synthesis of acetylcholine from choline derived from phosphatidylcholine in a human neuronal cell line. Proc Natl Acad Sci U S A 84, 5474–5477.
5SH Zeisel & KA da Costa (2009) Choline: an essential nutrient for public health. Nutr Rev 67, 615–623.
7JC McCann , M Hudes & BN Ames (2006) An overview of evidence for a causal relationship between dietary availability of choline during development and cognitive function in offspring. Neurosci Biobehav Rev 30, 696–712.
8CD Albright , MH Mar , CB Friedrich , et al. (2001) Maternal choline availability alters the localization of p15Ink4B and p27Kip1 cyclin-dependent kinase inhibitors in the developing fetal rat brain hippocampus. Dev Neurosci 23, 100–106.
9CD Albright , AY Tsai , MH Mar , et al. (1998) Choline availability modulates the expression of TGFbeta1 and cytoskeletal proteins in the hippocampus of developing rat brain. Neurochem Res 23, 751–758.
10SJ Wong-Goodrich , MJ Glenn , TJ Mellott , et al. (2008) Spatial memory and hippocampal plasticity are differentially sensitive to the availability of choline in adulthood as a function of choline supply in utero. Brain Res 1237, 153–166.
12S Grantham-McGregor , YB Cheung , S Cueto , et al. (2007) Developmental potential in the first 5 years for children in developing countries. Lancet 369, 60–70.
14SH Ryan , JK Williams & JD Thomas (2008) Choline supplementation attenuates learning deficits associated with neonatal alcohol exposure in the rat: effects of varying the timing of choline administration. Brain Res 1237, 91–100.
15BC Ward , NH Kolodny , N Nag , et al. (2009) Neurochemical changes in a mouse model of Rett syndrome: changes over time and in response to perinatal choline nutritional supplementation. J Neurochem 108, 361–371.
16SH Zeisel (2006) The fetal origins of memory: the role of dietary choline in optimal brain development. J Pediatr 149, S131–S136.
18BTF Wu , RA Dyer , DJ King , et al. (2012) Early second trimester maternal plasma choline and betaine are related to measures of early cognitive development in term infants. PLoS One 7, e43448.
19FJ Rosales , JS Reznick & SH Zeisel (2009) Understanding the role of nutrition in the brain and behavioral development of toddlers and preschool children: identifying and addressing methodological barriers. Nutr Neurosci 12, 190–202.
20A Busche , A Bagorda , K Lehmann , et al. (2006) The maturation of the acetylcholine system in the dentate gyrus of gerbils (Meriones unguiculatus) is affected by epigenetic factors. J Neural Transm 113, 113–124.
21JD Sweatt (2010) Neuroscience. Epigenetics and cognitive aging. Science 328, 701–702.
22TL Roth , ED Roth & JD Sweatt (2010) Epigenetic regulation of genes in learning and memory. Essays Biochem 48, 263–274.
24M de Onis , AW Onyango , E Borghi , et al. (2007) Development of a WHO growth reference for school-aged children and adolescents. Bull World Health Organ 85, 660–667.
28PI Holm , PM Ueland , G Kvalheim , et al. (2003) Determination of choline, betaine, and dimethylglycine in plasma by a high-throughput method based on normal-phase chromatography-tandem mass spectrometry. Clin Chem 49, 286–294.
29PW Davidson , GJ Myers , C Cox , et al. (1998) Effects of prenatal and postnatal methylmercury exposure from fish consumption on neurodevelopment: outcomes at 66 months of age in the Seychelles Child Development Study. JAMA 280, 701–707.
30TW Chew , X Jiang , J Yan , et al. (2011) Folate intake, MTHFR genotype, and sex modulate choline metabolism in mice. J Nutr 141, 1475–1481.
31S Weisberg (2005) Applied Linear Regression. New York, NY: Wiley.
32JJ Strain , PW Davidson , SW Thurston , et al. (2012) Maternal PUFA status but not prenatal methylmercury exposure is associated with children's language functions at age five years in the Seychelles. J Nutr 142, 1943–1949.
34TV Perneger (1998) What's wrong with Bonferroni adjustments? BMJ 316, 1236–1238.
35N Nag & JE Berger-Sweeney (2007) Postnatal dietary choline supplementation alters behavior in a mouse model of Rett syndrome. Neurobiol Dis 26, 473–480.
36WH Meck , RA Smith & CL Williams (1988) Pre- and postnatal choline supplementation produces long-term facilitation of spatial memory. Dev Psychobiol 21, 339–353.
37RK Cheng , CJ MacDonald , CL Williams , et al. (2008) Prenatal choline supplementation alters the timing, emotion, and memory performance (TEMP) of adult male and female rats as indexed by differential reinforcement of low-rate schedule behavior. Learn Mem 15, 153–162.
38SJ Eussen , PM Ueland , R Clarke , et al. (2007) The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people. Br J Nutr 98, 960–968.
39EY Shen , KH Wu , MF Lin , et al. (2010) Study of brain growth in children – a new approach to volume measurements using MRI-reconstructed 3D neuroimaging. Childs Nerv Syst 26, 1619–1623.
40J Dobbing & J Sands (1973) Quantitative growth and development of human brain. Arch Dis Child 48, 757–767.
41FJ Rosales & SH Zeisel (2008) Perspectives from the symposium: the role of nutrition in infant and toddler brain and behavioral development. Nutr Neurosci 11, 135–143.
42J Klein , A Koppen , K Loffelholz , et al. (1992) Uptake and metabolism of choline by rat brain after acute choline administration. J Neurochem 58, 870–876.
43SH Zeisel (2004) Nutritional importance of choline for brain development. J Am Coll Nutr 23, 621S–626S.
44F Amenta & SK Tayebati (2008) Pathways of acetylcholine synthesis, transport and release as targets for treatment of adult-onset cognitive dysfunction. Curr Med Chem 15, 488–498.
45SM Innis , AG Davidson , BN Bay , et al. (2011) Plasma choline depletion is associated with decreased peripheral blood leukocyte acetylcholine in children with cystic fibrosis. Am J Clin Nutr 93, 564–568.