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1EJ Lennon , J Lemann Jr & JR Litzow (1966) The effects of diet and stool composition on the net external acid balance of normal subjects. J Clin Invest 45, 1601–1607.
2AD Goodman , J Lemann Jr, EJ Lennon , (1965) Production, excretion, and net balance of fixed acid in patients with renal acidosis. J Clin Invest 44, 495–506.
3I Kurtz , JA Kraut , V Ornekian , (2008) Acid–base analysis: a critique of the Stewart and bicarbonate-centered approaches. Am J Physiol Renal Physiol 294, F1009–F1031.
4F Manz (2001) History of nutrition and acid–base physiology. Eur J Nutr 40, 189–199.
5DA Story (2004) Bench-to-bedside review: a brief history of clinical acid–base. Crit Care 8, 253–258.
6LA Frassetto , RC Morris Jr & A Sebastian (2007) Dietary sodium chloride intake independently predicts the degree of hyperchloremic metabolic acidosis in healthy humans consuming a net acid-producing diet. Am J Physiol Renal Physiol 293, F521–F525.
10SL Gluck (1998) Acid–base. Lancet 352, 474–479.
14A Brandao-Burch , JC Utting , IR Orriss , (2005) Acidosis inhibits bone formation by osteoblasts in vitro by preventing mineralization. Calcif Tissue Int 77, 167–174.
17KK Frick , NS Krieger , K Nehrke , (2009) Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1. J Bone Miner Res 24, 305–313.
18T Buclin , M Cosma , M Appenzeller , (2001) Diet acids and alkalis influence calcium retention in bone. Osteoporos Int 12, 493–499.
19WS Yancy Jr, MK Olsen , T Dudley , (2007) Acid–base analysis of individuals following two weight loss diets. Eur J Clin Nutr 61, 1416–1422.
20L Frassetto , RC Morris Jr, DE Sellmeyer , (2001) Diet, evolution and aging – the pathophysiologic effects of the post-agricultural inversion of the potassium-to-sodium and base-to-chloride ratios in the human diet. Eur J Nutr 40, 200–213.
21A Sebastian , ST Harris , JH Ottaway , (1994) Improved mineral balance and skeletal metabolism in postmenopausal women treated with potassium bicarbonate. N Engl J Med 330, 1776–1781.
22L Frassetto , RC Morris Jr & A Sebastian (2005) Long-term persistence of the urine calcium-lowering effect of potassium bicarbonate in postmenopausal women. J Clin Endocrinol Metab 90, 831–834.
23PJ Osther (2006) Effect of acute acid loading on acid–base and calcium metabolism. Scand J Urol Nephrol 40, 35–44.
25PJ Osther , J Bollerslev , AB Hansen , (1993) Pathophysiology of incomplete renal tubular acidosis in recurrent renal stone formers: evidence of disturbed calcium, bone and citrate metabolism. Urol Res 21, 169–173.
26S Domrongkitchaiporn , W Stitchantrakul & W Kochakarn (2006) Causes of hypocitraturia in recurrent calcium stone formers: focusing on urinary potassium excretion. Am J Kidney Dis 48, 546–554.
27L Borghi , T Schianchi , T Meschi , (2002) Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria. N Engl J Med 346, 77–84.
28A Trinchieri , R Lizzano , F Marchesotti , (2006) Effect of potential renal acid load of foods on urinary citrate excretion in calcium renal stone formers. Urol Res 34, 1–7.
29WE Mitch , R Medina , S Grieber , (1994) Metabolic acidosis stimulates muscle protein degradation by activating the adenosine triphosphate-dependent pathway involving ubiquitin and proteasomes. J Clin Invest 93, 2127–2133.
31J Du & WE Mitch (2005) Identification of pathways controlling muscle protein metabolism in uremia and other catabolic conditions. Curr Opin Nephrol Hypertens 14, 378–382.
32JA Kraut & NE Madias (2007) Serum anion gap: its uses and limitations in clinical medicine. Clin J Am Soc Nephrol 2, 162–174.
39T Remer & F Manz (1995) Potential renal acid load of foods and its influence on urine pH. J Am Diet Assoc 95, 791–797.
40DS Michaud , RP Troiano , AF Subar , (2003) Comparison of estimated renal net acid excretion from dietary intake and body size with urine pH. J Am Diet Assoc 103, 1001–1007.
41SJ Whiting & JA Muirhead (2005) Measurement of net acid excretion by use of paper strips. Nutrition 21, 961–963.
42R Jajoo , L Song , H Rasmussen , (2006) Dietary acid-base balance, bone resorption, and calcium excretion. J Am Coll Nutr 25, 224–230.
43F Pietschmann , NA Breslau & CY Pak (1992) Reduced vertebral bone density in hypercalciuric nephrolithiasis. J Bone Miner Res 7, 1383–1388.
48BA Ince , EJ Anderson & RM Neer (2004) Lowering dietary protein to U.S. recommended dietary allowance levels reduces urinary calcium excretion and bone resorption in young women. J Clin Endocrinol Metab 89, 3801–3807.
49T Remer (2001) Influence of nutrition on acid–base balance – metabolic aspects. Eur J Nutr 40, 214–220.
52P Frings-Meuthen , N Baecker & M Heer (2008) Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 23, 517–524.
53JA Kellum (2000) Determinants of blood pH in health and disease. Crit Care 4, 6–14.
54AM Sharma , A Kribben , S Schattenfroh , (1990) Salt sensitivity in humans is associated with abnormal acid–base regulation. Hypertension 16, 407–413.
55J Lemann Jr, RW Gray & JA Pleuss (1989) Potassium bicarbonate, but not sodium bicarbonate, reduces urinary calcium excretion and improves calcium balance in healthy men. Kidney Int 35, 688–695.
57RM Bersin , K Chatterjee & AI Arieff (1989) Metabolic and hemodynamic consequences of sodium bicarbonate administration in patients with heart disease. Am J Med 87, 7–14.
59R Coppoolse , TJ Barstow , WW Stringer , (1997) Effect of acute bicarbonate administration on exercise responses of COPD patients. Med Sci Sports Exerc 29, 725–732.
62K Sakhaee , NM Maalouf , SA Abrams , (2005) Effects of potassium alkali and calcium supplementation on bone turnover in postmenopausal women. J Clin Endocrinol Metab 90, 3528–3533.
63DE Sellmeyer , M Schloetter & A Sebastian (2002) Potassium citrate prevents increased urine calcium excretion and bone resorption induced by a high sodium chloride diet. J Clin Endocrinol Metab 87, 2008–2012.
64B Teucher , JR Dainty , CA Spinks , (2008) Sodium and bone health: the impact of moderately high and low salt intakes on calcium metabolism in postmenopausal women. J Bone Miner Res 23, 1477–1485.
65F Vescini , A Buffa , G La Manna , (2005) Long-term potassium citrate therapy and bone mineral density in idiopathic calcium stone formers. J Endocrinol Invest 28, 218–222.
66S Jehle , A Zanetti , J Muser , (2006) Partial neutralization of the acidogenic Western diet with potassium citrate increases bone mass in postmenopausal women with osteopenia. J Am Soc Nephrol 17, 3213–3222.
68B Dawson-Hughes , SS Harris , NJ Palermo , (2009) Treatment with potassium bicarbonate lowers calcium excretion and bone resorption in older men and women. J Clin Endocrinol Metab 94, 96–102.
70TR Fenton , AW Lyon , M Eliasziw , (2009) Meta-analysis of the effect of the acid-ash hypothesis of osteoporosis on calcium balance. J Bone Miner Res 24, 1835–1840.
71J Lemann Jr (1999) Relationship between urinary calcium and net acid excretion as determined by dietary protein and potassium: a review. Nephron 81, Suppl. 1, 18–25.
72JE Zerwekh , CV Odvina , LA Wuermser , (2007) Reduction of renal stone risk by potassium-magnesium citrate during 5 weeks of bed rest. J Urol 177, 2179–2184.
73PO Schwille , A Schmiedl , U Herrmann , (1999) Magnesium, citrate, magnesium citrate and magnesium-alkali citrate as modulators of calcium oxalate crystallization in urine: observations in patients with recurrent idiopathic calcium urolithiasis. Urol Res 27, 117–126.
74LA Frassetto , E Nash , RC Morris Jr, (2000) Comparative effects of potassium chloride and bicarbonate on thiazide-induced reduction in urinary calcium excretion. Kidney Int 58, 748–752.
75Y Kato , S Yamaguchi , S Yachiku , (2004) Changes in urinary parameters after oral administration of potassium-sodium citrate and magnesium oxide to prevent urolithiasis. Urology 63, 7–12.
76B Ettinger , CY Pak , JT Citron , (1997) Potassium-magnesium citrate is an effective prophylaxis against recurrent calcium oxalate nephrolithiasis. J Urol 158, 2069–2073.
77E Löfberg , A Gutierrez , B Anderstam , (2006) Effect of bicarbonate on muscle protein in patients receiving hemodialysis. Am J Kidney Dis 48, 419–429.
79L Frassetto , RC Morris Jr & A Sebastian (1997) Potassium bicarbonate reduces urinary nitrogen excretion in postmenopausal women. J Clin Endocrinol Metab 82, 254–259.
80F Douroudos II, IG atouros , V Gourgoulis , (2006) Dose-related effects of prolonged NaHCO3 ingestion during high-intensity exercise. Med Sci Sports Exerc 38, 1746–1753.
81D Bishop & B Claudius (2005) Effects of induced metabolic alkalosis on prolonged intermittent-sprint performance. Med Sci Sports Exerc 37, 759–767.
82L McNaughton , K Backx , G Palmer , (1999) Effects of chronic bicarbonate ingestion on the performance of high-intensity work. Eur J Appl Physiol Occup Physiol 80, 333–336.
83GH Raymer , GD Marsh , JM Kowalchuk , (2004) Metabolic effects of induced alkalosis during progressive forearm exercise to fatigue. J Appl Physiol 96, 2050–2056.
84AM Lindh , MC Peyrebrune , SA Ingham , (2008) Sodium bicarbonate improves swimming performance. Int J Sports Med 29, 519–523.
85D Ball , PL Greenhaff & RJ Maughan (1996) The acute reversal of a diet-induced metabolic acidosis does not restore endurance capacity during high-intensity exercise in man. Eur J Appl Physiol Occup Physiol 73, 105–112.
86A Cupisti , M Meola , C D'Alessandro , (2007) Insulin resistance and low urinary citrate excretion in calcium stone formers. Biomed Pharmacother 61, 86–90.
87M Daudon , O Traxer , P Conort , (2006) Type 2 diabetes increases the risk for uric acid stones. J Am Soc Nephrol 17, 2026–2033.
88MA Cameron , NM Maalouf , B Adams-Huet , (2006) Urine composition in type 2 diabetes: predisposition to uric acid nephrolithiasis. J Am Soc Nephrol 17, 1422–1428.
89NM Maalouf , MA Cameron , OW Moe , (2007) Low urine pH: a novel feature of the metabolic syndrome. Clin J Am Soc Nephrol 2, 883–888.
90N Abate , M Chandalia , JAV Cabo-Chan Jr, (2004) The metabolic syndrome and uric acid nephrolithiasis: novel features of renal manifestation of insulin resistance. Kidney Int 65, 386–392.
91F Birklein , M Weber , M Ernst , (2000) Experimental tissue acidosis leads to increased pain in complex regional pain syndrome (CRPS). Pain 87, 227–234.
92B Duan , LJ Wu , YQ Yu , (2007) Upregulation of acid-sensing ion channel ASIC1a in spinal dorsal horn neurons contributes to inflammatory pain hypersensitivity. J Neurosci 27, 11139–11148.
93H Cadiou , M Studer , NG Jones , (2007) Modulation of acid-sensing ion channel activity by nitric oxide. J Neurosci 27, 13251–13260.
94WZ Wang , XP Chu , MH Li , (2006) Modulation of acid-sensing ion channel currents, acid-induced increase of intracellular Ca2+, and acidosis-mediated neuronal injury by intracellular pH. J Biol Chem 281, 29369–29378.