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MR Adams & P Marteau (1995) On the safety of lactic acid bacteria from food. International Journal of Food Microbiology 27, 262–264.
M Aguirre & MD Collins (1993) Lactic acid bacteria and human clinical infection. Journal of Applied Bacteriology 75, 95–107.
M Alander , R Korpela , M Saxelin , T Vilpponon-Salmila , T Mattila-Sandholm & A von Wright (1996) Recovery of Lactobacillus rhamnosus GG from human colonic biopsies. Letters in Applied Microbiology 24, 361–364.
B Ansari , PJ Coates , B Greenstein & PA Hall (1993) In situ end labelling (ISEL) detects DNA strand breaks in apoptosis and in other physiological and pathological states. Journal of Pathology 170, 1–8.
Y Aso & H Akazan (1992) Prophylactic effect of Lactobacillus casei preparation on the recurrence of superficial bladder cancer. Urology International 49, 125–129.
A Awad , PJ Horvath & MS Anderson (1991) Influence of butyrate on lipid metabolism, survival, and differentiation Of colon cancer cells. Nutrition and Cancer 16, 125–133.
J Ballongue , C Schumann & P Quignon (1997) Effects of lactulose and lactitol on colonic microflora and enzymatic activity. Scandinavian Journal of Gastroenterology 32, Suppl. 222, 41–44.
L Bedenne , J Faivre , MC Boutron , F Piard , JM Cauvin & P Hillon (1992) Adenoma-carcinoma sequence or 'de novo' carcinogenesis? A study of adenomatous remnants in a population-based series of large bowel cancers. Cancer 69, 883–888.
N Benlounes , C Dupont , C Candahl , MA Blaton , JF Desjeux & M Heyman (1996) The threshold for immune cell reactivity to milk antigens decreases in cow's milk allergy with intestinal symptoms. Journal of Allergy and Clinical Immunology 98, 781–789.
Y Benno , F He , M Hosoda , H Hashimoto , T Kojima , K Yamazaki , H Iino , H Mykkänen & S Salminen (1996) Effects of Lactobacillus GG yogurt on human intestinal microecology in Japanese subjects. Nutrition Today 31, 9–11.
J Biewenga , EP Rees & T Sminia (1993) Induction and regulation of IgA responses in the microenvironment of the gut. Short analytical review. Clinical Immunology and Immunopathology 67, 1–7.
MC Boutron & J Faivre (1993) Diet and the adenoma-carcinoma sequence. European Journal of Cancer Prevention 2, 95–98.
MC Boutron , J Faivre , P Marteau , C Couillaut , P Senesse & V Quipourt (1996) Calcium, phosphorus, vitamin D, products and colorectal carcinogenesis: a French case-control study. British Journal of Cancer 74, 145–151.
P Brandtzaeg (1995) Molecular and cellular aspects of the secretory immunoglobulin system. Acta Pathologica, Microbiologica et Immunologica Scandinavica 103, 1–19.
P Brandtzaeg , TS Halstensen , K Kett , P Krajci , D Kvale , TO Rognum , H Scott & LM Sollid (1989) Immunobiology and immuno-pathology of human gut mucosa: humoral immunity and intraepithelial lymphocytes. Gastroenterology 97, 1562–1584.
L Bry , PG Falk , T Midtvedt & J Gordon (1996) A model for host-microbial interactions in an open mammalian ecosystem. Science 273, 1380–1383.
M Bugaut & M Bentejac (1993) Biological effects of short-chain fatty acids in nonruminant mammals. Annual Review of Nutrition 13, 217–241.
DP Burkitt (1971) Epidemiology of cancer of the colon and rectum. Cancer 28, 3–13.
JH Cummings , SA Bingham , KW Heaton & MA Eastwood (1992) Faecal weight, colon cancer risk and dietary intake of non-starch polysaccharides (dietary fiber). Gastroenterology 103, 1783–1789.
JH Cummings , EW Pomare , WJ Branch , CPE Naylor & GT Macfarlane (1987) Short chain fatty acids in human large intestine, portal, hepatic and venous blood. Gut 28, 1221–1227.
JH Cummings , MB Roberfroid , H Anderson , C Barth , A Ferro-Luzzi , Y Ghoos , M Gibney , K Hermonsen , WPT James , O Korver , D Lairon , G Pascal & AGS Voragen (1997) A new look at dietary carbohydrate: chemistry, physiology and health. European Journal of Clinical Nutrition 51, 417–423.
R Duchmann , I Kaiser , E Hermann , W Mayet , K Ewe & KH Meyer zum Büschenfelde (1995) Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD). Clinical and Experimental Immunology 102, 448–455.
MJ Fargeas , V Theodorou , J More , JM Wal , J Fioramonti & L Bueno (1995) Boosted systemic immune and local responsiveness after intestinal inflammation in orally sensitized guinea pigs. Gastroenterology 109, 53–62.
WL Frankel , W Zhang , A Singh , DM Klurfeld , S Don , T Sakata , I Modlin & JL Rombeau (1994) Mediation of the trophic effects of short-chain fatty acids on the rat jejunum and colon. Gastroenterology 106, 375–380.
R Fuller (1991) Probiotics in human medicine. Gut 32, 439–442.
V Gaboriau-Routhiau & MC Moreau (1996) Gut flora allows recovery of oral tolerance to ovalbumin in mice after transient breakdown mediated by cholera toxin or Escherichia coli heat-labile enterotoxin. Pediatrics Research 39, 625–629.
GR Gibson , ER Beatty , X Wang & JH Cummings (1995) Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin. Gastroenterology 108, 975–982.
PR Gibson , I Moeller , O Kagelari , M Folino & GP Young (1992) Contrasting effects of butyrate on the expression of phenotypic markers of differentiation in neoplastic and non-neoplastic colonic epithelial cells in vitro. Journal of Gastroenterology and Hepatology 7, 165–172.
RA Goodlad (1989) Gastrointestinal cell proliferation. Digestive Diseases 7, 169–177.
M Gracey (1993) Transmission and epidemiology. Bailliere's Clinical Gastroenterology 7, 195–214.
ER Greenberg , JA Baron , TD Tosteson , DH Freeman Jr, GJ Beck , JH Bond , TA Colacchio , JA Coller , HD Frankl & RW Haile (1994) A clinical trial of antioxidant vitamins to prevent colorectal adenoma. New England Journal of Medicine 331, 141–147.
A Guarino , RB Canani , MI Spagnuolo , F Albano & LD Benedetto (1997) Oral bacterial therapy reduces the duration of symptoms and of viral excretion in children with mild diarrhoea. Journal of Pediatric Gastroenterology and Nutrition (In the Press).
A Hague , AM Manning , KA Hanlon , LI Huschtscha , D Hart & C Paraskeva (1993) Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer. International Journal of Cancer 55, 498–505.
RJ Hambly , CJ Rumney , JME Fletcher , P Rijken & IR Rowland (1997) Effects of high and low risk diets on gut-microflora-associated biomarkers of colon cancer in human-flora-associated rats. Nutrition and Cancer 27, 250–255.
M Heyman & JF Desjeux (1992) Significance of intestinal food protein transport. Journal of Pediatric Gastroenterology and Nutrition 15, 48–57.
M Heyman , G Gorthier , A Petit , J-C Mesh , C Moreau & J-F Desjeux (1987) Intestinal absorption of macromolecules during viral enteritis: an experimental study on rotavirus-infected conventional and germ-free mice. Pediatrics Research 22, 72–78.
G Howe , E Benito , R Casteleto , J Cornée , J Estéve , RP Gallagher , JM Iscovich , J Deng-ao , R Kaaks , GA Kune , S Kune , KA L'AbbC , HP Lee , AB Miller , RK Peters , JD Potter , E Riboli , ML Slattery , D Trichopoulos , A Tuyns , A Tzonou , AS Whittemore , AH Wu-Williams & S Zeng (1992) Dietary intake of fiber and decreased risk of cancers of the colon and rectum: evidence from the combined analysis of 13 case–control studies. Journal of the National Cancer Institute 84, 1887–1896.
E Isolauri , M Kaila , T Arvola , H Majamaa , I Rantala , E Virtanen & H Arvilommi (1993 a) Diet during rotavirus enteritis affects jejunal permeability to macromolecules in suckling rats. Pediatrics Research 33, 548–553.
E Isolauri , H Majamaa , T Arvola , I Rantala , F Virtanen & H Arvilommi (1993 b) Lactobacillus casei strain GG reverses increased intestinal permeability induced by cow milk in suckling rats. Gastroenterology 105, 1643–1650.
M Ito , M Kimura , Y Deguchi , A Miyamori-Watabe , T Yajima & T Kan (1993) Effects of transgalactosylated disaccharides on the human intestinal microflora and their metabolism. Journal of Nutritional Science and Vitaminology 39, 279–288.
T Jalonen , E Isolauri , M Heyman , A-M Crain-Denoyelle , P Sillanaukee & T Koivula (1991) Increased β-lactoglobulin absorption during rotavirus enteritis in infants: relationship to sugar permeability. Pediatrics Research 30, 290–293.
M Kaila , E Isolauri , E Soppi , V Virtanen , S Laine & H Arvilommi (1992) Enhancement of the circulating antibody secreting cell response in human diarrhea by a human Lactobacillus strain. Pediatrics Research 32, 141–144.
YS Kim , D Tsao , B Siddiqui , JS Whitehead , P Arnstein , J Bennett & J Hicks (1980) Effects of sodium butyrate and dimethylsulf-oxide on biochemical properties of human colon cancer cells. Cancer 45, 1185–1192.
JC Kolars , MD Levitt , M Aouiji & DA Savaiano (1984) Yogurt – an autodigesting source of lactose. New England Journal of Medicine 310, 1–3.
YK Lee & S Salminen (1995) The coming of age of probiotics. Trends in Food Science Technology 6, 241–245.
CH Lifschitz , FR Carrazza , AS Feste & PD Klein (1995) In vivo study of colonic fermentation of carbohydrate in infants. Journal of Paediatric Gastroenterology and Nutrition 20, 59–64.
TT MacDonald (1993) Aetiology of Crohn's disease. Archives of Disease in Childhood 68, 623–625.
A McIntyre , PR Gibson & GP Young (1993) Butyrate production from dietary fibre and protection against large bowel cancer in a rat model. Gut 34, 386–391.
A McIntyre , GP Young , T Taranto , PR Gibson & PB Ward (1991) Different fibres have different regional effects on luminal contents of rat colon. Gastroenterology 101, 1274–1281.
DM McKay & MH Perdue (1993) Intestinal epithelial function: the case for immunophysiological regulation. Cells and mediators (First of two parts). Digestive Diseases and Sciences 38, 1377–1387.
R MacLennan , F Macrae , C Bain , D Battistutta , P Chapuis , H Gratten , J Lambert , RC Newland , M Ngu & A Russell (1995) Randomized trial of intake of fat, fiber, and beta carotene to prevent colorectal adenomas. Journal of the National Cancer Institute 87, 1760–1766.
P Marteau , M Minekus , R Havenaar & JHJ Huis in't Veld (1997 a) Survival of lactic acid bacteria in a dynamic model of the stomach and small intestine: validation and the effects of bile. Journal of Dairy Science 80, 1031–1037.
P Marteau & JC Rambaud (1993) Potential for using lactic acid bacteria for therapy and immunomodulation in man. FEMS Microbiology Review 12, 207–220.
MS Martin , E Justrabo , JF Jeannin , A Leclerc & F Martin (1981) Effect of dietary chenodeoxycholic acid on intestinal carcino-genesis induced by 1,2 dimethylhydrazine in mice and hamsters. British Journal of Cancer 43, 884–886.
AP Maskens & RM Dujardin Loits (1981) Experimental adenomas and carcinomas of the large intestine behave as distinct entities. Cancer 47, 81–89.
MC Moreau & M Coste (1993) Immune responses to dietary protein antigens. World Review of Nutrition and Dietetics 74, 22–57.
MC Moreau & V Gaboriau-Routhiau (1996) The absence of gut flora, the doses of antigen ingested and aging affect the long-term peripheral tolerance induced by ovalbumin feeding in mice. Research Immunology 147, 49–59.
T Mosmann (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferative and cytotoxic assays. Journal of Immunology Methods 65, 55–63.
AR Pant , SM Graham , SJ Allen , S Harikul , A Sabohaeron , L Cuevas & CA Hart (1996) Lactobacillus GG and acute diarrhoea in young children in the tropics. Journal of Tropical Pediatrics 42, 162–165.
G Perdigon , S Alvarez , M Rachid , G Agüero & N Gobatto (1996) Probiotic bacteria for humans: clinical systems for evaluation of effectiveness. Journal of Dairy Science 78, 1597–1606.
MCL Pitcher & JH Cummings (1996) Hydrogen sulphide: a bacterial toxin in ulcerative colitis? Gut 39, 1–4.
DK Podolsky (1991) Inflammatory bowel disease. (First of two parts.) New England Journal of Medicine 325, 928–937.
EW Pomare , WJ Branch & JH Cummings (1985) Carbohydrate fermentation in the human colon and its relation to acetate concentration in venous blood. Journal of Clinical Investigation 75, 1448–1454.
S Raza , SM Graham , SJ Allen , S Sultana , L Cuevas & CA Hart (1995) Lactobacillus GG promotes recovery from acute non-bloody diarrhoea in Pakistan. Pediatric Infection and Disease 14, 107–111.
JK Ritchie , J Wadsworth , JE Lennard-Jones & E Rogers (1987) Controlled multicentre therapeutic trial of an unrefined carbohydrate, fibre-rich diet in Crohn's disease. British Medical Journal 295, 517–520.
MB Roberfroid (1996) Functional effects of food components and the gastrointestinal system: chicory fructooligosaccharides. Nutrition Reviews 54, S38–S42.
MB Roberfroid , F Bornet , C Bouley & JH Cummings (1995) Colonic microflora: nutrition and health. Nutrition Reviews 53, 127–130.
M Roberfroid , GR Gibson & N Delzenne (1993) The biochemistry of oligofructose, a non-digestible fiber: an approach to calculate its caloric value. Nutrition Reviews 51, 137–146.
WEW Roediger , A Duncan , O Kapaniris & S Millard (1993) Reducing sulfur compounds of the colon impair colonocyte nutrition: implications for ulcerative colitis. Gastroenterology 104, 802–809.
JM Saavedra , NA Bauman , I Oung , JA Perman & RH Yolken (1994) Feeding of Bijidobacterium bijidum and Streptococcus thermophilus to infants in hospital for prevention of diarrhoea and shedding of rotavirus. Lancet 344, 1046–1049.
J Sakamoto , N Shigeyuki , K Sugawara , S Iwane & A Munakata (1996) Comparison of resistant starch with cellulose diet on 1,2-dimethylhydrazine-induced colonic carcinogenesis in rats. Gastroenterology 110, 116–120.
S Salminen , E Isolauri & E Salminen (1996 a) Clinical uses of probiotics for stabilizing the gut mucosal barrier: successful strains and future challenges. Anton. Leeuwenhoek 70, 347–358.
S Salminen , M Laine , A Wright , J Vuopio-Varkila , T Korhonen & T Mattila-Sandholm (1996 c) Development of selection criteria for probiotic strains to assess their potential in functional foods: a Nordic and European approach. Bioscience Microflora 15, 61–67.
ME Sanders (1993) Summary of the conclusions from a consensus panel of experts on health attributes on lactic cultures: significance to fluid milk products containing cultures. Journal of Dairy Science 76, 1819–1828.
SJ Savarino & AL Bourgeois (1993) Diarrhoea1 disease: current concepts and future challenges. Epidemiology of diarrhoea1 diseases in developed countries. Transcript of the Royal Society of Tropical Medicine and Hygiene 87, 7–11.
M Saxelin , NH Chuang , B Chassy , H Rautelin , PH Mäkelä , S Salminen & SL Gorbach (1996 a) Lactobacilli and bacteremia in Southern Finland, (1989–1992). Clinical Infection and Disease 22, 564–566.
M Saxelin , H Rautelin , S Salminen & P Mäkelä (1996 b) The safety of commercial products with viable Lactoba-cillus strains. Infection and Disease in Clinical Practice 5, 331–335.
E Schiffrin , F Rochat , H Link-Amster , J Aeschlimann & A Donnet-Hugues (1995) Immunomodulation of blood cells following the ingestion of lactic acid bacteria. Journal of Dairy Science 78, 491–497.
AV Shornikova , I Casas , E Isolauri , H Mykkänen & T Vesikari (1997) Lactobacillus reuteri as a therapeutic agent in acute diarrhea in young children. Journal of Pediatric Gastroenterology and Nutrition 24, 399–404.
B Solis-Pereyra & D Lemonnier (1996) Induction of human cytokines by bacteria used in dairy foods. Nutrition Research 13, 1127–1140.
Y Sütas , M Hurme & E Isolauri (1996 a) Downregulation of antiCD3 antibody-induced IL-4 production by bovine caseins hydrolysed with Lactobacillus GG-derived enzymes. Scandinavian Journal of Immunology 43, 687–689.
Y Sütas , E Soppi , H Korhonen , EL Syväoja , M Saxelin , T Rokka & E Isolauri (1996 b) Suppression of lymphocyte proliferation in vitro by bovine caseins hydrolysed with Lactobacillus GG-derived enzymes. Journal of Allergy and Clinical Immunology 98, 216–224.
A Terada , H Hara , M Kataoka & T Mitsuoka (1992) Effect of lactulose on the composition and metabolic activity of the human faecal flora. Microbial Ecology in Health and Disease 5, 43–50.
WG Thompson & JE Gomborone (1993) Irritable bowel syndrome: pathogenesis and management. Lancet 341, 1569–1572.
B Trock , E Lanza & P Greenwald (1990) Dietary fiber, vegetables, and colon cancer: critical review and meta-analyses of the epidemiologic evidence. Journal of the National Cancer Institute 82, 650–661.
Y Umesaki (1989) Intestinal glycolipids and their role in intestinal colonization of mice. Bifidobacteria Microflora 8, 13–22.
Y Umesaki , Y Okada , A Imaoka , H Setoyama & S Matsumoto (1997) Interactions between epithelial cells and bacteria, normal and pathogenic. Science 276, 964–965.
Y Umesaki , Y Okada , S Matsumoto , A Imaoka & H Setoyama (1995) Segmented filamentous bacteria are indigenous intestinal bacteria that activate intraepithelial lymphocytes and induce MHC class I1 molecules and fucosyl asialoGMl glycolipids on the small intestinal epithelial cells in ex-gem-free mouse. Microbial Immunology 39, 555–562.
J Van Loo , P Coussement , L De Leenheer , H Hoebregs & G Smits (1995) On the presence of inulin and oligofructose as natural ingredients in the Western diet. Critical Reviews in Food Science and Nutrition 35, 525–552.
IP van Munster , A Tangerman & FM Nagengast (1994) Effect of resistant starch on colonic fermentation, bile acid metabolism, and mucosal proliferation. Digestive Diseases and Sciences 39, 834–842.
M Venturi , RJ Hambly , B Glinghammar , JJ Rafter & IR Rowland (1997) Genotoxic activity in human faecal water and the role of bile acids: a study using the Comet assay. Carcinogenesis (In the Press).
HS Wasan & RA Goodlad (1996) Fibre-supplemented foods may damage your health. Lancet 348, 319–320.
HL Weiner , A Friedman , A Miller , SJ Khoury , A Al-Sabbagh , L Santos , M Sayegh , RB Nussenblatt , DE Trentham & DA Hafler (1994) Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens. Annual Review of Immunology 12, 809–837.
RH Whitehead , GP Young & PS Bathal (1986) Effects of short chain fatty acids on a new human colon carcinoma cell line (LIM 1215). Gut 27, 1457–1463.
GP Young , A McIntyre , V Albert , M Folino , JG Muir & PR Gibson (1996) Wheat bran suppresses potato-starch potentiated colorectal tumorigenesis at the aberrant crypt stage in a rat model. Gastroenterology 110, 508–514.