Skip to main content
×
Home
    • Aa
    • Aa

Goitre decline in Italy and contribution of the silent and active prophylaxis

  • Venanzio Vella (a1)
Abstract

Goitre has been declining in Italy since the 1970s and because active prophylaxis (AP) has been very limited, it has been suggested that in most places the decline was due to silent prophylaxis (SP). SP is related to the natural increase in iodine intake because of higher consumption of iodine-rich products associated with socioeconomic development. The hypothesis tested in the present study is that SP has increased iodine intake in Italy with subsequent reduction of goitre and that such changes can be quantified. The analysis is based on surveys carried out between the 1970s and the 1990s where goitre and urinary iodine, a proxy of consumption, were measured in schoolchildren. The contribution of the SP can be quantified in an annual increase in urinary iodine excretion between 2·1 and 4μg/l, and an annual decline in goitre prevalence between 2·1 and 3·6%. In the few areas with AP, there was an annual increase in urinary iodine between 6·5 and 13·1μg/l, while the average annual decline of goitre was between 4·4 and 10%. The present results could be used by policy-makers to predict the future trends in the excretion of urinary iodine and prevalence of goitre in Italy with and without AP. AP is about three times faster than SP in increasing iodine intake, but policy-makers should estimate the incremental cost-effectiveness of AP net of the iodine increase already occurring naturally with the SP.

    • Send article to Kindle

      To send this article to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Goitre decline in Italy and contribution of the silent and active prophylaxis
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      Goitre decline in Italy and contribution of the silent and active prophylaxis
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      Goitre decline in Italy and contribution of the silent and active prophylaxis
      Available formats
      ×
Copyright
Corresponding author
*Corresponding author: Dr Venanzio Vella, fax +27 33 3952211, email Thevellas@yahoo.it
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

F Aghini-Lombardi , A Pinchera & L Antonangeli (1995) Mild iodine deficiency during fetal/neonatal life and neuropsychological impairment in Tuscany. J Endocrinol Invest 18, 5762.

F Delange , A Van Onderbergen W Shabana , E Vandemeulebroucke , F Vertongen , D Gnat & M Dramaix (2000) Silent iodine prophylaxis in Western Europe only partly corrects iodine deficiency; the case of Belgium. Eur J Endocrinol 143, 189196.

C Regalbuto , S Squatrito , GL La Rosa , G Cercabene , A Ippolito , P Tita , S Salamone & R Vigneri (1996) Longitudinal study on goiter prevalence and goitrogen factors in northeastern Sicily. J Endocrinol Invest 19, 638645.

F Vermiglio , MD Finocchiaro , VP Lo Presti , N La Torre , M Nucifora & F Trimarchi (1989) Partial beneficial effects of the so called ‘silent iodine prophylaxis’ on iodine deficiency disorders (IDD) in Northeastern Sicily endemia. J Endocrinol Invest 12, 123126.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords: