Skip to main content
×
Home
    • Aa
    • Aa
  • Access
  • Cited by 2
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    König, Daniel Zdzieblik, Denise Deibert, Peter Berg, Aloys Gollhofer, Albert and Büchert, Martin 2015. Internal Fat and Cardiometabolic Risk Factors Following a Meal-Replacement Regimen vs. Comprehensive Lifestyle Changes in Obese Subjects. Nutrients, Vol. 7, Issue. 12, p. 9825.


    Stevens, John W. Khunti, Kamlesh Harvey, Rebecca Johnson, Maxine Preston, Louise Woods, Helen Buckley Davies, Melanie and Goyder, Elizabeth 2015. Preventing the progression to Type 2 diabetes mellitus in adults at high risk: A systematic review and network meta-analysis of lifestyle, pharmacological and surgical interventions. Diabetes Research and Clinical Practice, Vol. 107, Issue. 3, p. 320.


    ×

Effects of lifestyle intervention and meal replacement on glycaemic and body-weight control in Chinese subjects with impaired glucose regulation: a 1-year randomised controlled trial

  • Dan-Feng Xu (a1), Jian-Qin Sun (a1), Min Chen (a1), Yan-Qiu Chen (a1), Hua Xie (a1), Wei-Jia Sun (a1), Yi-Fan Lin (a1), Jing-Jing Jiang (a1), Wei Sun (a2), Ai-Fang Chen (a2) and Qian-Ru Tang (a3)
  • DOI: http://dx.doi.org/10.1017/S0007114512001328
  • Published online: 05 July 2012
Abstract

The purpose of the present study was to evaluate the impact of a lifestyle intervention programme, combined with a daily low-glycaemic index meal replacement, on body-weight and glycaemic control in subjects with impaired glucose regulation (IGR). Subjects with IGR were randomly assigned to an intervention group (n 46) and a control group (n 42). Both groups received health counselling at baseline. The intervention group also received a daily meal replacement and intensive lifestyle intervention to promote healthy eating habits during the first 3 months of the study, and follow-up visits performed monthly until the end of the 1-year study. Outcome measurements included changes in plasma glucose, glycated Hb (HbA1c), plasma lipids, body weight, blood pressure and body composition (such as body fat mass and visceral fat area). The results showed that body-weight loss after 1 year was significant in the intervention group compared with the control group ( − 1·8 (sem 0·35) v.− 0·6 (sem 0·40) 2·5 kg, P< 0·05). The 2 h plasma glucose concentration decreased 1·24 mmol/l in the intervention group and increased 0·85 mmol/l in the control group (P< 0·05) compared with their baseline, respectively. A 5 kg body-weight loss at 1 year was associated with a decrease of 1·49 mmol/l in 2 h plasma glucose (P< 0·01). The incidence of normal glucose regulation (NGR) in the two groups was significantly different (P= 0·001). In conclusion, the combination of regular contact, lifestyle advice and meal replacement is beneficial in promoting IGR to NGR.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Effects of lifestyle intervention and meal replacement on glycaemic and body-weight control in Chinese subjects with impaired glucose regulation: a 1-year randomised controlled trial
      Your Kindle email address
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      Effects of lifestyle intervention and meal replacement on glycaemic and body-weight control in Chinese subjects with impaired glucose regulation: a 1-year randomised controlled trial
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      Effects of lifestyle intervention and meal replacement on glycaemic and body-weight control in Chinese subjects with impaired glucose regulation: a 1-year randomised controlled trial
      Available formats
      ×
Copyright
Corresponding author
*Corresponding author: J.-Q. Sun, fax +86 21 32140503, E-mail: jianqins@gmail.com
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1XR Pan , WY Yang , GW Li , et al. (1997) Prevalence of diabetes and its risk factors in China, 1994. National Diabetes Prevention and Control Cooperative Group. Diabetes Care 20, 16641669.

2D Gu , K Reynolds , X Duan , et al. (2003) Prevalence of diabetes and impaired fasting glucose in the Chinese adult population: International Collaborative Study of Cardiovascular Disease in Asia (InterASIA). Diabetologia 46, 11901198.

3WY Yang , JM Lu , JP Weng , et al. (2010) Prevalence of diabetes among men and women in China. New Engl J Med 362, 10901101.

4KG Alberti & PZ Zimmet (1998) Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 15, 539553.

5DM Nathan , MB Davidson , RA DeFronzo , et al. (2007) Impaired fasting glucose and impaired glucose tolerance – implications for care. Diabetes Care 30, 753759.

7YS Levitzky , MJ Pencina , RB D'Agostino , et al. (2008) Impact of impaired fasting glucose on cardiovascular disease: the Framingham Heart Study. J Am Coll Cardiol 51, 264270.

8KL Chien , HC Hsu , TC Su , et al. (2008) Fasting and postchallenge hyperglycemia and risk of cardiovascular disease in Chinese: the Chin-Shan Community Cardiovascular Cohort study. Am Heart J 156, 9961002.

12J Tuomilehto , J Lindstrom , JG Eriksson , et al. (2001) Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. New Engl J Med 344, 13431350.

13KF Eriksson & F Lindgarde (1991) Prevention of Type-2 (non-insulin-dependent) diabetes-mellitus by diet and physical exercise. The 6-year Malmo feasibility study. Diabetologia 34, 891898.

16TA Wadden , DS West , RH Neiberg , et al. (2009) One-year weight losses in the Look AHEAD study: factors associated with success. Obesity 17, 713722.

21SB Heymsfield , CAJ van Mierlo , HC van der Knaap , et al. (2003) Weight management using a meal replacement strategy: meta and pooling analysis from six studies. Int J Obes Relat Metab Disord 27, 537549.

22LP Svetkey , VJ Stevens , PJ Brantley , et al. (2008) Comparison of strategies for sustaining weight loss – the weight loss maintenance randomized controlled trial. JAMA 299, 11391148.

24JB Redmon , SK Raatz , KP Reck , et al. (2003) One-year outcome of a combination of weight loss therapies for subjects with type 2 diabetes: a randomized trial. Diabetes Care 26, 25052511.

25SL Edelstein , WC Knowler , RP Bain , et al. (1997) Predictors of progression from impaired glucose tolerance to NIDDM: an analysis of six prospective studies. Diabetes 46, 701710.

29JL Chiasson , RG Josse , R Gomis , et al. (2002) Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet 359, 20722077.

31L Perreault , SE Kahn , CA Christophi , et al. (2009) Regression from pre-diabetes to normal glucose regulation in the diabetes prevention program. Diabetes Care 32, 15831588.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords: