Skip to main content
×
Home
    • Aa
    • Aa
  • Access
  • Cited by 13
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Jutzeler van Wijlen, Remo P. 2011. Long-term conjugated linoleic acid supplementation in humans - effects on body composition and safety. European Journal of Lipid Science and Technology, Vol. 113, Issue. 9, p. 1077.


    McCrorie, Tracy A. Keaveney, Edel M. Wallace, Julie M. W. Binns, Nino and Livingstone, M. Barbara E. 2011. Human health effects of conjugated linoleic acid from milk and supplements. Nutrition Research Reviews, Vol. 24, Issue. 02, p. 206.


    Mills, S. Ross, R.P. Hill, C. Fitzgerald, G.F. and Stanton, C. 2011. Milk intelligence: Mining milk for bioactive substances associated with human health. International Dairy Journal, Vol. 21, Issue. 6, p. 377.


    McAfee, Alison J. McSorley, Emeir M. Cuskelly, Geraldine J. Moss, Bruce W. Wallace, Julie M.W. Bonham, Maxine P. and Fearon, Anna M. 2010. Red meat consumption: An overview of the risks and benefits. Meat Science, Vol. 84, Issue. 1, p. 1.


    Sofi, F. Buccioni, A. Cesari, F. Gori, A.M. Minieri, S. Mannini, L. Casini, A. Gensini, G.F. Abbate, R. and Antongiovanni, M. 2010. Effects of a dairy product (pecorino cheese) naturally rich in cis-9, trans-11 conjugated linoleic acid on lipid, inflammatory and haemorheological variables: A dietary intervention study. Nutrition, Metabolism and Cardiovascular Diseases, Vol. 20, Issue. 2, p. 117.


    Subbaiah, Papasani V. Sircar, Debajit Aizezi, Buzulagu and Mintzer, Evan 2010. Differential effects of conjugated linoleic acid isomers on the biophysical and biochemical properties of model membranes. Biochimica et Biophysica Acta (BBA) - Biomembranes, Vol. 1798, Issue. 3, p. 506.


    Venkatramanan, Sudha Joseph, Shama V Chouinard, P. Yvan Jacques, Helene Farnworth, Edward R and Jones, Peter J.H 2010. Milk Enriched with Conjugated Linoleic Acid Fails to Alter Blood Lipids or Body Composition in Moderately Overweight, Borderline Hyperlipidemic Individuals. Journal of the American College of Nutrition, Vol. 29, Issue. 2, p. 152.


    Blewett, Heather J. Gerdung, Christopher A. Ruth, Megan R. Proctor, Spencer D. and Field, Catherine J. 2009. Vaccenic acid favourably alters immune function in obese JCR:LA- cp rats. British Journal of Nutrition, Vol. 102, Issue. 04, p. 526.


    Yuan, Gaofeng Sinclair, Andrew J. Xu, Chaojiong and Li, Duo 2009. Incorporation and metabolism of punicic acid in healthy young humans. Molecular Nutrition & Food Research, Vol. 53, Issue. 10, p. 1336.


    Plourde, Mélanie Jew, Stephanie Cunnane, Stephen C and Jones, Peter JH 2008. Conjugated linoleic acids: why the discrepancy between animal and human studies?. Nutrition Reviews, Vol. 66, Issue. 7, p. 415.


    Givens, D.I. Kliem, Kirsty E. and Gibbs, Rachael A. 2006. The role of meat as a source of n−3 polyunsaturated fatty acids in the human diet. Meat Science, Vol. 74, Issue. 1, p. 209.


    Yaqoob, P. Tricon, S. Williams, C. M. Grimble, R. F. Burdge, G. C. and Calder, P. C. 2006. Conjugated linoleic acid and human health-related outcomes. Nutrition Bulletin, Vol. 31, Issue. 2, p. 93.


    2006. Handbook of Dairy Foods and Nutrition, Third Edition.


    ×

Incorporation of cis-9, trans-11 conjugated linoleic acid and vaccenic acid (trans-11 18:1) into plasma and leucocyte lipids in healthy men consuming dairy products naturally enriched in these fatty acids

Abstract

The present study investigated whether consuming dairy products naturally enriched in cis-9, trans-11 (c9, t11) conjugated linoleic acid (CLA) by modification of cattle feed increases the concentration of this isomer in plasma and cellular lipids in healthy men. The study had a double-blind cross-over design. Subjects aged 34–60 years consumed dairy products available from food retailers for 1 week and then either control (0·17 g c9, t11 CLA/d; 0·31 g trans-vaccenic acid (tVA)/d) or CLA-enriched (1·43 g c9, t11 CLA/d; 4·71 g tVA/d) dairy products for 6 weeks. After 7 weeks washout, this was repeated with the alternate products. c9, t11 CLA concentration in plasma lipids was lower after consuming the control products, which may reflect the two-fold greater c9, t11 CLA content of the commercial products. Consuming the CLA-enriched dairy products increased the c9, t11 CLA concentration in plasma phosphatidylcholine (PC) (38%; P=0·035), triacylglycerol (TAG) (22%; P<0·0001) and cholesteryl esters (205%; P<0·0001), and in peripheral blood mononuclear cells (PBMC) (238%; P<0·0001), while tVA concentration was greater in plasma PC (65%; P=0·035), TAG (98%; P=0·001) and PBMC (84%; P=0·004). Overall, the present study shows that consumption of naturally enriched dairy products in amounts similar to habitual intakes of these foods increased the c9, t11 CLA content of plasma and cellular lipids.

    • Send article to Kindle

      To send this article to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Incorporation of cis-9, trans-11 conjugated linoleic acid and vaccenic acid (trans-11 18:1) into plasma and leucocyte lipids in healthy men consuming dairy products naturally enriched in these fatty acids
      Your Kindle email address
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      Incorporation of cis-9, trans-11 conjugated linoleic acid and vaccenic acid (trans-11 18:1) into plasma and leucocyte lipids in healthy men consuming dairy products naturally enriched in these fatty acids
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      Incorporation of cis-9, trans-11 conjugated linoleic acid and vaccenic acid (trans-11 18:1) into plasma and leucocyte lipids in healthy men consuming dairy products naturally enriched in these fatty acids
      Available formats
      ×
Copyright
Corresponding author
*Corresponding author: Dr Graham C. Burdge, fax +44 2380 594379, email g.c.burdge@soton.ac.uk
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

C Alasnier , O Berdeaux , JM Chardigny & JL Sebedio (2002) Fatty acid composition and conjugated linoleic acid content of different tissues in rats fed individual conjugated linoleic acid isomers given as triacylglycerols. J Nutr Biochem 13, 337345.

R Albers , RP van der Wielen , EJ Brink , HF Hendriks , VN Dorovska-Taran & IC Mohede (2003) Effects of cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid (CLA) isomers on immune function in healthy men. Eur J Clin Nutr 57, 595603.

P Benito , GJ Nelson , DS Kelley , G Bartolini , PC Schmidt & V Simon (2001) The effect of conjugated linoleic acid on plasma lipoproteins and tissue fatty acid composition in humans. Lipids 36, 229236.

GC Burdge , B Lupoli , JJ Russell , et al. (2004) Incorporation of cis-9, trans-11 or trans-10, cis-12 conjugated linoleic acid into plasma and cellular lipids in healthy men. J Lipid Res 45, 736741.

PC Calder (2002) Conjugated linoleic acid in humans - reasons to be cheerful? Curr Opin Clin Nutr Metab Care 5, 123126.

JM Griinari , DA Dwyer , MA McGuire , DE Bauman , DL Palmquist & KVV Nurmela (1998) Trans-octadecenoic acids and milk fat depression in lactating dairy cows. J Dairy Sci 81, 12511261.

EL Jones , KJ Shingfield , C Kohen , AK Jones , B Lupoli , AS Grandison , DE Beever , CM Williams , PC Calder & P Yaqoob (2005) Chemical, physical and sensory properties of diary products enriched with conjugated linoleic acid. J Dairy Sci (In the Press).

DS Kelley & KL Erickson (2003) Modulation of body composition and immune cell functions by conjugated linoleic acid in humans and animal models: benefits vs. risks. Lipids 38, 377386.

DS Kelley , VA Simon , PC Taylor , IL Rudolph , P Benito , GJ Nelson , BE Mackey & KL Erickson (2001) Dietary supplementation with conjugated linoleic acid increased its concentration in human peripheral blood mononuclear cells, but did not alter their function. Lipids 36, 669674.

RE Lawson , AR Moss & DI Givens (2001) The role of dairy products in supplying conjugated linoleic acid to man's diet: a review. Nutr Res 14, 153172.

KN Lee , D Kritchevsky & MW Pariza (1994) Conjugated linoleic acid and atherosclerosis in rabbits. Atherosclerosis 108, 1925.

C Malpuech-Brugere , WP Verboeket-Van de Venne , RP Mensink , et al. (2004) Effects of two conjugated linoleic acid isomers on body fat mass in overweight humans. Obes Res 12, 591598.

N Masters , MA McGuire , KA Beerman , N Dasgupta & MK McGuire (2002) Maternal supplementation with CLA decreases milk fat in humans. Lipids 37, 133138.

V Mougios , A Matsakas , A Petridou , S Ring , A Sagredos , A Melissopoulou , N Tsigilis & M Nikolaidis (2001) Effect of supplementation with conjugated linoleic acid on human serum lipids and body fat. J Nutr Biochem 12, 585594.

Y Park , KJ Albright , W Liu , JM Storkson , ME Cook & MW Pariza (1997) Effect of conjugated linoleic acid on body composition in mice. Lipids 32, 853858.

A Petridou , V Mougios & A Sagredos (2003) Supplementation with CLA: isomer incorporation in serum lipids and effect on body fat of women. Lipids 38, 805811.

HM Roche , E Noone , A Nugent & MJ Gibney (2001) Conjugated linoleic acid: a novel therapeutic nutrient? Nutr Res 14, 173187.

JL Sebedio , E Angioni , JM Chardigny , S Gregoire , P Juaneda & O Berdeaux (2001) The effect of conjugated linoleic acid isomers on fatty acid profiles of liver and adipose tissues and their conversion to isomers of 16:2 and 18:3 conjugated fatty acids in rats. Lipids 36, 575582.

C Von Loeffelholz , J Kratzsch & G Jahreis (2003) Influence of conjugated linoleic acids on body composition and selected serum and endocrine parameters in resistance-trained athletes. Eur J Lipid Sci Technol 105, 251259.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords: