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Iron deficiency is uncommon among lactating women in urban Nepal, despite a high risk of inadequate dietary iron intake

  • Sigrun Henjum (a1), Mari Manger (a2), Eli Skeie (a2), Manjeswori Ulak (a3), Andrew L. Thorne-Lyman (a4) (a5), Ram Chandyo (a2) (a3), Prakash S. Shrestha (a3), Lindsey Locks (a4), Rune J. Ulvik (a6) (a7), Wafaie W. Fawzi (a4) (a8) (a9) and Tor A. Strand (a2) (a10)...
Abstract

The main objective of the present study was to examine the association between dietary Fe intake and dietary predictors of Fe status and Hb concentration among lactating women in Bhaktapur, Nepal. We included 500 randomly selected lactating women in a cross-sectional survey. Dietary information was obtained through three interactive 24 h recall interviews including personal recipes. Concentrations of Hb and plasma ferritin and soluble transferrin receptors were measured. The daily median Fe intake from food was 17·5 mg, and 70 % of the women were found to be at the risk of inadequate dietary Fe intake. Approximately 90 % of the women had taken Fe supplements in pregnancy. The prevalence of anaemia was 20 % (Hb levels < 123 g/l) and that of Fe deficiency was 5 % (plasma ferritin levels < 15 μg/l). In multiple regression analyses, there was a weak positive association between dietary Fe intake and body Fe (β 0·03, 95 % CI 0·014, 0·045). Among the women with children aged < 6 months, but not those with older infants, intake of Fe supplements in pregnancy for at least 6 months was positively associated with body Fe (P for interaction < 0·01). Due to a relatively high dietary intake of non-haem Fe combined with low bioavailability, a high proportion of the women in the present study were at the risk of inadequate intake of Fe. The low prevalence of anaemia and Fe deficiency may be explained by the majority of the women consuming Fe supplements in pregnancy.

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*Corresponding author: S. Henjum, email sigrun.henjum@hioa.no
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3MB Zimmermann & RF Hurrell (2007) Nutritional iron deficiency. Lancet 370, 511520.

4RK Chandyo , TA Strand , RJ Ulvik , et al. (2007) Prevalence of iron deficiency and anemia among healthy women of reproductive age in Bhaktapur, Nepal. Eur J Clin Nutr 61, 262269.

6Z Makhoul , D Taren , B Duncan , et al. (2012) Risk factors associated with anemia, iron deficiency and iron deficiency anemia in rural Nepali pregnant women. Southeast Asian J Trop Med Public Health 43, 735746.

8LE Torheim , EL Ferguson , K Penrose , et al. (2010) Women in resource-poor settings are at risk of inadequate intakes of multiple micronutrients. J Nutr 140, 2051S2058S.

12Institute of Nutrition Mahidol University (2002) Food Composition Database for INMUCAL Program. Thailand: Institute of Nutrition.

14J Haubrock , U Nothlings , JL Volatier , et al. (2011) Estimating usual food intake distributions by using the multiple source method in the EPIC-Potsdam Calibration Study. J Nutr 141, 914920.

15U Harttig , J Haubrock , S Knuppel , et al. (2011) The MSM program: web-based statistics package for estimating usual dietary intake using the Multiple Source Method. Eur J Clin Nutr 65, Suppl. 1, S87S91.

16SP Murphy , GH Beaton & DH Calloway (1992) Estimated mineral intakes of toddlers: predicted prevalence of inadequacy in village populations in Egypt, Kenya, and Mexico. Am J Clin Nutr 56, 565572.

19World Health Organization, Food and Agriculture Organization of the United Nations (2006) Guidelines for Food Fortification with Micronutrients [LH Allen , B de Benois , O Dary and R Hurrell , editors]. Geneva: World Health Organization, Food and Agriculture Organization of the United Nations.

20 WHO (2006) Global Database on Body Mass Index: An Interactive Surveillance Tool for Monitoring Nutrition Transition. Geneva: WHO.

23S Kolbe-Busch , J Lotz , G Hafner , et al. (2002) Multicenter evaluation of a fully mechanized soluble transferrin receptor assay on the Hitachi and Cobas Integra analysers. The determination of reference ranges. Clin Chem Lab Med 40, 529536.

24JD Cook , CH Flowers & BS Skikne (2003) The quantitative assessment of body iron. Blood 101, 33593364.

26CM Pfeiffer , JD Cook , Z Mei , et al. (2007) Evaluation of an automated soluble transferrin receptor (sTfR) assay on the Roche Hitachi analyzer and its comparison to two ELISA assays. Clin Chim Acta 382, 112116.

27DW Hosmer & S Lemeshow (2000) Applied Logistic Regression, 2nd ed.New York: John Wiley & Sons.

28SN Wood (2000) Modelling and smoothing parameter estimation with multiple quadratic penalties. J R Statist Soc B 62, 413428.

29L Hallberg , C Bengtsson , L Lapidus , et al. (1993) Screening for iron deficiency: an analysis based on bone-marrow examinations and serum ferritin determinations in a population sample of women. Br J Haematol 85, 787798.

30TH Bothwell , RW Charlton , JD Cook , et al. (1979) Iron Metabolism in Man. Oxford, UK: Blackwell Scientific Publications.

31PB Moser , RD Reynolds , S Acharya , et al. (1988) Copper, iron, zinc, and selenium dietary intake and status of Nepalese lactating women and their breast-fed infants. Am J Clin Nutr 47, 729734.

33RC Suma , G Sheetal , LA Jyothi , et al. (2007) Influence of phytin phosphorous and dietary fibre on in vitro iron and calcium bioavailability from rice flakes. Int J Food Sci Nutr 58, 637643.

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British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
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