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Mammalian small intestinal phytase (EC 3.1.3.8)

Published online by Cambridge University Press:  24 July 2007

John R. Cooper
Affiliation:
National Radiological Protection Board, Chilton, Didcot, Oxon OX11 0RQ
Helen S. Gowing
Affiliation:
National Radiological Protection Board, Chilton, Didcot, Oxon OX11 0RQ
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Abstract

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1. Phytase (EC 3.1.3.8) concentration has been measured in the small intestineof rat, rabbit, guinea-pig and hamster. Levels varied from 0·12 units (μg phosphorus released/min)/mg protein in the rat to 0·03 units/mg protein in the rabbit.

2. The enzyme is localized in the brush border of the small intestine of the rat.

3. It is suggested that the levels and location of phytase are an important factor inthe uptake of metals from metal–phytate complexes. Metal ions released in the immediate vicinity of the absorptive surface of the intestine could be absorbed before being rendered insoluble by competing reactions such as hydrolysis.

Type
Research Article
Copyright
Copyright © The Nutrition Society 1983

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