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    Dong, Shan Zhang, Ran Ji, Ya-Cheng Hao, Jia-Yin Ma, Wei-Wei Chen, Xu-Dong Xiao, Rong and Yu, Huan-Ling 2016. Soy milk powder supplemented with phytosterol esters reduced serum cholesterol level in hypercholesterolemia independently of lipoprotein E genotype: a random clinical placebo-controlled trial. Nutrition Research, Vol. 36, Issue. 8, p. 879.


    Musa-Veloso, Kathy Poon, Theresa H. Elliot, Julie Ann and Chung, Catherine 2011. A comparison of the LDL-cholesterol lowering efficacy of plant stanols and plant sterols over a continuous dose range: Results of a meta-analysis of randomized, placebo-controlled trials. Prostaglandins, Leukotrienes and Essential Fatty Acids, Vol. 85, Issue. 1, p. 9.


    Marinangeli, Christopher P. F. and Jones, Peter J. H. 2010. Functional Food Product Development.


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Plant sterol-enriched milk tea decreases blood cholesterol concentrations in Chinese adults: a randomised controlled trial

  • Nicole Y. Li (a1), Keji Li (a2), Zhi Qi (a2), Isabelle Demonty (a3), Michelle Gordon (a3), Lesley Francis (a1), Henri O. F. Molhuizen (a3) and Bruce C. Neal (a1)
  • DOI: http://dx.doi.org/10.1017/S0007114507754302
  • Published online: 01 November 2007
Abstract

The cholesterol-lowering effects of plant sterols in a format suitable for use in China have not previously been investigated. We conducted the study to quantify in adult Chinese the effects on blood lipid concentrations of a plant sterol-enriched milk tea powder. The study was a double-blind, randomised trial in which 309 participants were randomised to receive daily 2·3 or 1·5 g plant sterol supplementation or placebo for 5 weeks. The milk tea was consumed with the two fattiest meals of the day with half the assigned daily dose taken on each occasion. Fasting venous blood samples were collected before commencement and upon completion of randomised treatment. The mean age of study participants was 44 years, 62 % were female and 62 % had a history of hypercholesterolaemia. Baseline mean total cholesterol was 5·5 mmol/l and LDL-cholesterol was 3·2 mmol/l. Compared with placebo, the 2·3 g/d plant sterol dose reduced total cholesterol by 0·25 (95 % CI 0·07, 0·43) mmol/l (P = 0·01) and the 1·5 g/d dose by 0·23 (95 % CI 0·06, 0·41) mmol/l (P = 0·01). For LDL-cholesterol the corresponding reductions were 0·17 (95 % CI 0·00, 0·35) mmol/l (P = 0·06) and 0·15 (95 % CI − 0·02, 0·32) mmol/l (P = 0·08). For neither outcome was there evidence of differences between the effects of the two doses (both P values >0·4). In conclusion, the consumption of plant sterol-enriched milk tea decreased cholesterol concentrations although to a lesser extent than was anticipated. The reason for reduced efficacy is unclear but may be attributable to the novel food format used or the Chinese population studied.

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*Corresponding author: Dr Nicole Li, fax +61 2 9993 4502, email nli@george.org.au
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Anonymous (1995) Cholesterol, diastolic blood pressure, and stroke: 13,000 strokes in 450,000 people in 45 prospective cohorts. Prospective studies collaboration. Lancet 346, 16471653.

AH Lichtenstein & RJ Deckelbaum (2001) Stanol/sterol ester-containing foods and blood cholesterol levels. A statement for healthcare professionals from the Nutrition Committee of the Council on Nutrition, Physical Activity, and Metabolism of the American Heart Association. Circulation 103, 11771179.

EA Trautwein , GS Duchateau , Y Lin , SM Mel'nikov , HO Molhuizen & FY Ntanios (2003) Proposed mechanisms of cholesterol-lowering action of plant sterols. Eur J Lipid Sci Technol 105, 171185.

MB Katan , SM Grundy , P Jones , M Law , TA Miettinen & R Paoletti (2003) Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels. Mayo Clin Proc 78, 965978.

TA Miettinen , P Puska , H Gylling , H Vanhanen & E Vartiainen (1995) Reduction of serum cholesterol with sitostanol-ester margarine in a mildly hypercholesterolemic population. N Engl J Med 333, 13081312.

YJ Hyun , OY King , JB Kang , JH Lee , Y Jang , L Liponkoski & P Salo (2005) Plant stanol esters in low-fat yogurt reduces total and low-density lipoprotein cholesterol and low density lipoprotein oxidation in normocholesterolemic and mildly hypercholesterolemic subjects. Nutr Res 25, 743753.

L Simons (2002) Additive effect of plant sterol-ester margarine and cerivastatin in lowering low density lipoprotein cholesterol in primary hypercholesterolemia. Am J Cardiol 90, 737740.

J He , D Gu , K Reynolds , , InterASIA Collaborative Group (2004) Serum total and lipoprotein cholesterol levels and awareness, treatment, and control of hypercholesterolemia in China. Circulation 110, 405411.

N Chung , SY Cho , DH Choi , (2001) STATT: a titrate-to-goal study of simvastatin in Asian patients with coronary heart disease. Simvastatin Treats Asians to Target. Clin Ther 23, 858870.

M-J Shin , S-J Rim , Y Jang , D Choi , S-M Kang , S-Y Cho , SS Kim , D Kim , K Song & N Chung (2003) The cholesterol-lowering effect of plant sterol-containing beverage in hypercholesterolemic subjects with low cholesterol intake. Nutr Res 23, 489496.

M Noakes , PM Clifton , AME Doornbos & EA Trautwein (2004) Plant sterol ester-enriched milk and yoghurt effectively reduce serum cholesterol in modestly hypercholesterolemic subjects. Eur J Nutr 44, 214222.

S Devaraj , I Jialal & S Vega-Lopez (2004) Plant sterol-fortified orange juice effectively lowers cholesterol levels in mildly hypercholesterolemic healthy individuals. Arterioscler Thromb Vasc Biol 24, e25e28.

PJH Jones , CA Vanstone , M Raeini-Sarjaz & M-P St-Onge (2003) Phytosterols in low- and nonfat beverages as part of a controlled diet fail to lower plasma lipid levels. J Lipid Res 44, 17131719.

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British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
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