1Mori, M, Kawada, T & Torii, K (1991) Appetite and taste preference in growing rats given various levels of protein nutrition. Brain Res Bull 27, 417–422.
2Chang, YF (1976) Pipecolic acid pathway: the major lysine metabolic route in the rat brain. Biochem Biophys Res Commun 69, 174–180.
3Chang, YF & Gao, XM (1995) l-Lysine is a barbiturate-like anticonvulsant and modulator of the benzodiazepine receptor. Neurochem Res 20, 931–937.
4Conigrave, AD, Quinn, SJ & Brown, EM (2000) l-Amino acid sensing by the extracellular Ca2+-sensing receptor. Proc Natl Acad Sci U S A 97, 4814–4819.
5Wellendorph, P, Hansen, KB, Balsgaard, A, et al. (2005) Deorphanization of GPRC6A: a promiscuous l-alpha-amino acid receptor with preference for basic amino acids. Mol Pharmacol 67, 589–597.
6Smriga, M, Murakami, H, Mori, M, et al. (2000) Effects of l-lysine deficient diet on the hypothalamic interstitial norepinephrine and diet-induced thermogenesis in rats in vivo. Biofactors 12, 137–142.
7Smriga, M, Kameishi, M, Uneyama, H, et al. (2002) Dietary l-lysine deficiency increases stress-induced anxiety and fecal excretion in rats. J Nutr 132, 3744–3746.
8Hrupka, BJ, Lin, Y, Gietzen, DW, et al. (1999) Lysine deficiency alters diet selection without depressing food intake in rats. J Nutr 129, 424–430.
9Tsurugizawa, T, Uematsu, A, Uneyama, H, et al. (2010) Effects of isoflurane and alpha-chloralose anesthesia on BOLD fMRI responses to ingested l-glutamate in rats. Neuroscience 165, 244–251.
10Tsurugizawa, T, Uematsu, A, Uneyama, H, et al. (2009) Blood oxygenation level-dependent response to intragastric load of corn oil emulsion in conscious rats. Neuroreport 20, 1625–1629.
11Paxinos, G & Watson, C (1998) The Rat Brain in Stereotaxic Coodinates, 4th ed.San Diego, CA: Academic Press.
12Yokawa, T, Tabuchi, E, Takezawa, M, et al. (1995) Recognition and neural plasticity responding to deficient nutrient intake scanned by a functional MRI in the brain of rats with l-lysine deficiency. Obes Res 3, Suppl. 5, 685S–688S.
13King, JA, Garelick, TS, Brevard, ME, et al. (2005) Procedure for minimizing stress for fMRI studies in conscious rats. J Neurosci Methods 148, 154–160.
14Tsurugizawa, T, Kondoh, T & Torii, K (2008) Forebrain activation induced by postoral nutritive substances in rats. Neuroreport 19, 1111–1115.
15Berthoud, HR (2008) Vagal and hormonal gut–brain communication: from satiation to satisfaction. Neurogastroenterol Motil 20, Suppl. 1, 64–72.
16Ren, X, Ferreira, JG, Zhou, L, et al. (2010) Nutrient selection in the absence of taste receptor signaling. J Neurosci 30, 8012–8023.
17Min, DK, Tuor, UI, Koopmans, HS, et al. (2011) Changes in differential functional magnetic resonance signals in the rodent brain elicited by mixed-nutrient or protein-enriched meals. Gastroenterology 141, 1832–1841.
18Tsurugizawa, T, Uematsu, A, Nakamura, E, et al. (2009) Mechanisms of neural response to gastrointestinal nutritive stimuli: the gut–brain axis. Gastroenterology 137, 262–273.
19Uematsu, A, Tsurugizawa, T, Uneyama, H, et al. (2010) Brain–gut communication via vagus nerve modulates conditioned flavor preference. Eur J Neurosci 31, 1136–1143.
20Wang, SH, Crosby, LO & Nesheim, MC (1973) Effect of dietary excesses of lysine and arginine on the degradation of lysine by chicks. J Nutr 103, 384–391.
21Humphrey, BD, Stephensen, CB, Calvert, CC, et al. (2006) Lysine deficiency and feed restriction independently alter cationic amino acid transporter expression in chickens (Gallus gallus domesticus). Comp Biochem Physiol A Mol Integr Physiol 143, 218–227.
22de Araujo, IE, Gutierrez, R, Oliveira-Maia, AJ, et al. (2006) Neural ensemble coding of satiety states. Neuron 51, 483–494.
23Schultz, W (1997) Dopamine neurons and their role in reward mechanisms. Curr Opin Neurobiol 7, 191–197.
24Abbott, A (2002) Neuroscience: addicted. Nature 419, 872–874.
25Martinez-Hernandez, J, Lanuza, E & Martinez-Garcia, F (2006) Selective dopaminergic lesions of the ventral tegmental area impair preference for sucrose but not for male sexual pheromones in female mice. Eur J Neurosci 24, 885–893.
26Berridge, KC (2009) ‘Liking’ and ‘wanting’ food rewards: brain substrates and roles in eating disorders. Physiol Behav 97, 537–550.
27Meguid, MM, Fetissov, SO, Blaha, V, et al. (2000) Dopamine and serotonin VMN release is related to feeding status in obese and lean Zucker rats. Neuroreport 11, 2069–2072.
28Di Marzo, V, Ligresti, A & Cristino, L (2009) The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation. Int J Obes (Lond) 33, Suppl. 2, S18–S24.