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Sodium bicarbonated mineral water decreases postprandial lipaemia in postmenopausal women compared to a low mineral water

Published online by Cambridge University Press:  08 March 2007

Stefanie Schoppen*
Department of Metabolism and Nutrition, Instituto del Frío, Spanish Council for Scientific Research (CSIC), C/José Antonio Novais, 10, 28040 Madrid, Spain
Ana M. Pérez-Granados
Department of Metabolism and Nutrition, Instituto del Frío, Spanish Council for Scientific Research (CSIC), C/José Antonio Novais, 10, 28040 Madrid, Spain
Ángeles Carbajal
Department of Nutrition, Faculty of Pharmacy, Madrid Complutense University, Madrid, Spain
Beatriz Sarriá
Department of Metabolism and Nutrition, Instituto del Frío, Spanish Council for Scientific Research (CSIC), C/José Antonio Novais, 10, 28040 Madrid, Spain
Francisco J. Sánchez-Muniz
Department of Nutrition, Faculty of Pharmacy, Madrid Complutense University, Madrid, Spain
Juan A. Gómez-Gerique
Biochemical Service, Fundación Jimenez Díaz, Madrid, Spain
M. Pilar Vaquero
Department of Metabolism and Nutrition, Instituto del Frío, Spanish Council for Scientific Research (CSIC), C/José Antonio Novais, 10, 28040 Madrid, Spain
*Corresponding author: Dr Stefanie Schoppen, fax +34 915493627, email
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The role of bicarbonated mineral waters on lipid metabolism and lipoprotein concentrations in man has scarcely been investigated. The present study aimed to investigate whether drinking sodium bicarbonated mineral water affects postprandial cholesterol and triacylglycerol metabolism in postmenopausal women. In a three-way, randomised, crossover study, eighteen healthy postmenopausal women consumed two sodium bicarbonated mineral waters (bicarbonated mineral water 1 and bicarbonated mineral water 2) and a low mineral water (500 ml of each) with a standard fat-rich meal (4552 kJ; 75·3 g fat). The bicarbonated waters were rich in sodium and bicarbonate and bicarbonated mineral water 1 contained 5·7 times more fluoride than bicarbonated mineral water 2. Fasting blood samples and postprandial blood samples were taken at 30, 60, 120, 240, 360 and 420 min after the end of the meal consumption. Cholesterol and triacylglycerols were determined in serum and chylomicrons. A significant water consumption effect was observed in the total area under the curve (TAUC) of serum and chylomicron triacylglycerols (ANOVA, P=0·008 and P=0·027, respectively). TAUC of serum triacylglycerols for bicarbonated mineral water 2 was significantly lower compared to low mineral water (Bonferroni, P=0·039). Peak concentration of serum triacylglycerols showed a significant water effect (P=0·025). Changes in chylomicron cholesterol were not significantly affected by the type of water. Bicarbonated mineral waters 1 and 2 did not show any significant differences. Drinking sodium bicarbonate-rich mineral waters reduces postprandial lipaemia in healthy postmenopausal women compared to drinking a low mineral water.

Research Article
Copyright © The Nutrition Society 2005


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