Skip to main content
×
Home
    • Aa
    • Aa
  • Access
  • Cited by 16
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Nakamura, M. Sugiura, M. Ogawa, K. Ikoma, Y. and Yano, M. 2016. Serum β-cryptoxanthin and β-carotene derived from Satsuma mandarin and brachial–ankle pulse wave velocity: The Mikkabi cohort study. Nutrition, Metabolism and Cardiovascular Diseases,


    Ni, Yinhua Zhuge, Fen Nagashimada, Mayumi and Ota, Tsuguhito 2016. Novel Action of Carotenoids on Non-Alcoholic Fatty Liver Disease: Macrophage Polarization and Liver Homeostasis. Nutrients, Vol. 8, Issue. 7, p. 391.


    Sugiura, Minoru Nakamura, Mieko Ogawa, Kazunori Ikoma, Yoshinori and Yano, Masamichi 2016. High serum carotenoids are associated with lower risk for developing elevated serum alanine aminotransferase among Japanese subjects: the Mikkabi cohort study. British Journal of Nutrition, Vol. 115, Issue. 08, p. 1462.


    SUGIURA, Minoru NAKAMURA, Mieko OGAWA, Kazunori IKOMA, Yoshinori and YANO, Masamichi 2016. High Vitamin C Intake with High Serum β-Cryptoxanthin Associated with Lower Risk for Osteoporosis in Post-Menopausal Japanese Female Subjects: Mikkabi Cohort Study. Journal of Nutritional Science and Vitaminology, Vol. 62, Issue. 3, p. 185.


    Endoh, Kaori Kuriki, Kiyonori Kasezawa, Nobuhiko Tohyama, Kazushige and Goda, Toshinao 2015. Association between Smoking Status and Food and Nutrient Consumption in Japanese: a Large-Scale Cross-Sectional Study. Asian Pacific Journal of Cancer Prevention, Vol. 16, Issue. 15, p. 6527.


    Sugiura, Minoru Nakamura, Mieko Ogawa, Kazunori Ikoma, Yoshinori and Yano, Masamichi 2015. High serum carotenoids associated with lower risk for the metabolic syndrome and its components among Japanese subjects: Mikkabi cohort study. British Journal of Nutrition, Vol. 114, Issue. 10, p. 1674.


    Sugiura, Minoru Nakamura, Mieko Ogawa, Kazunori Ikoma, Yoshinori and Yano, Masamichi 2015. High-serum carotenoids associated with lower risk for developing type 2 diabetes among Japanese subjects: Mikkabi cohort study. BMJ Open Diabetes Research & Care, Vol. 3, Issue. 1, p. e000147.


    Yoshinaka, Masaki Ikebe, Kazunori Uota, Masahiro Ogawa, Taiji Okada, Tadashi Inomata, Chisato Takeshita, Hajime Mihara, Yusuke Gondo, Yasuyuki Masui, Yukie Kamide, Kei Arai, Yasumichi Takahashi, Ryutaro and Maeda, Yoshinobu 2015. Age and sex differences in the taste sensitivity of young adult, young-old and old-old Japanese. Geriatrics & Gerontology International, p. n/a.


    Sugiura, Minoru Ogawa, Kazunori and Yano, Masamichi 2014. Comparison of bioavailability between β-cryptoxanthin and β-carotene and tissue distribution in its intact form in rats. Bioscience, Biotechnology, and Biochemistry, Vol. 78, Issue. 2, p. 307.


    Darvin, M.E. Sterry, W. Lademann, J. and Patzelt, A. 2013. Alcohol Consumption Decreases the Protection Efficiency of the Antioxidant Network and Increases the Risk of Sunburn in Human Skin. Skin Pharmacology and Physiology, Vol. 26, Issue. 1, p. 45.


    Sugiura, M. 2013. Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease.


    Sugiura, M. Nakamura, M. Ogawa, K. Ikoma, Y. Ando, F. Shimokata, H. and Yano, M. 2011. Dietary patterns of antioxidant vitamin and carotenoid intake associated with bone mineral density: findings from post-menopausal Japanese female subjects. Osteoporosis International, Vol. 22, Issue. 1, p. 143.


    Unno, Keiko Sugiura, Minoru Ogawa, Kazunori Takabayashi, Fumiyo Toda, Masateru Sakuma, Midori Maeda, Ken-ichi Fujitani, Keisuke Miyazaki, Hideaki Yamamoto, Hiroyuki and Hoshino, Minoru 2011. Beta-Cryptoxanthin, Plentiful in Japanese Mandarin Orange, Prevents Age-Related Cognitive Dysfunction and Oxidative Damage in Senescence-Accelerated Mouse Brain. Biological & Pharmaceutical Bulletin, Vol. 34, Issue. 3, p. 311.


    Yamada, Tomoyo Hayasaka, Shinya Shibata, Yosuke Ojima, Toshiyuki Saegusa, Tomohiro Gotoh, Tadao Ishikawa, Shizukiyo Nakamura, Yosikazu and Kayaba, Kazunori 2011. Frequency of Citrus Fruit Intake Is Associated With the Incidence of Cardiovascular Disease: The Jichi Medical School Cohort Study. Journal of Epidemiology, Vol. 21, Issue. 3, p. 169.


    Epplein, M. Shu, X.-O. Xiang, Y.-B. Chow, W.-H. Yang, G. Li, H.-L. Ji, B.-T. Cai, H. Gao, Y.-T. and Zheng, W. 2010. Fruit and Vegetable Consumption and Risk of Distal Gastric Cancer in the Shanghai Women's and Men's Health Studies. American Journal of Epidemiology, Vol. 172, Issue. 4, p. 397.


    SUGIURA, Minoru 2010. KAGAKU TO SEIBUTSU, Vol. 48, Issue. 9, p. 622.


    ×

Synergistic interaction of cigarette smoking and alcohol drinking with serum carotenoid concentrations: findings from a middle-aged Japanese population

  • Minoru Sugiura (a1), Mieko Nakamura (a2), Kazunori Ogawa (a1), Yoshinori Ikoma (a1), Hikaru Matsumoto (a1), Fujiko Ando (a3), Hiroshi Shimokata (a4) and Masamichi Yano (a1)
  • DOI: http://dx.doi.org/10.1017/S0007114509382124
  • Published online: 19 May 2009
Abstract

Previous studies have indicated low serum carotenoid concentrations among cigarette smokers and/or alcohol drinkers, but little is known about the interaction of smoking and drinking with serum carotenoids. We tested the hypothesis that smoking and drinking reduce serum carotenoid concentrations synergistically. A total of 1073 subjects (357 male and 716 female) who had received health examinations in the town of Mikkabi, Shizuoka Prefecture, Japan, participated in the study. The subjects were divided into six groups according to alcohol intake (non-drinkers, < 1 g/d; light drinkers, ≥ 1, < 25 g/d; moderate-to-heavy drinkers, ≥ 25 g/d) and smoking status (non-smokers and current smokers). The dietary intakes and serum concentrations of six carotenoids (lycopene, α-carotene, β-carotene, lutein, β-cryptoxanthin and zeaxanthin) within each group were evaluated cross-sectionally. The dietary intakes of all carotenoids did not differ in the six groups after adjusting for age and sex. The multivariate-adjusted means of the serum carotenoid concentrations in non-drinkers did not differ between non-smokers and current smokers. In contrast, the adjusted means of serum α-carotene, β-carotene and β-cryptoxanthin were significantly lower than those with increased alcohol intake, and these lower serum carotenoids among alcohol drinkers were more evident in current smokers than in non-smokers. Serum lycopene of moderate-to-heavy drinkers was significantly lower than that of non-drinkers, but it was not influenced by smoking. Neither smoking nor drinking was associated with the serum concentrations of lutein and zeaxanthin. These results suggest that smoking and drinking may reduce the serum α-carotene, β-carotene and β-cryptoxanthin concentrations in a synergistic manner.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Synergistic interaction of cigarette smoking and alcohol drinking with serum carotenoid concentrations: findings from a middle-aged Japanese population
      Your Kindle email address
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      Synergistic interaction of cigarette smoking and alcohol drinking with serum carotenoid concentrations: findings from a middle-aged Japanese population
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      Synergistic interaction of cigarette smoking and alcohol drinking with serum carotenoid concentrations: findings from a middle-aged Japanese population
      Available formats
      ×
Copyright
Corresponding author
*Corresponding author: Dr Minoru Sugiura, fax +81 543 69 2115, email msugiura@affrc.go.jp
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1JM Gutteridge (1994) Biological origin of free radicals, and mechanisms of antioxidant protection. Chem Biol Interact 91, 133140.

2CL Rock , RA Jacob & PE Bowen (1996) Update on the biological characteristics of the antioxidant micronutrients: vitamin C, vitamin E, and the carotenoids. J Am Diet Assoc 96, 693702.

5J Montonen , R Jarvinen , M Heliovaara , (2005) Food consumption and the incidence of type II diabetes mellitus. Eur J Clin Nutr 59, 441448.

8ES Ford , JC Will , BA Bowman , (1999) Diabetes mellitus and serum carotenoids: findings from the Third National Health and Nutrition Examination Survey. Am J Epidemiol 149, 168176.

9DF Church & WA Pryor (1985) Free-radical chemistry of cigarette smoke and its toxicological implications. Environ Health Perspect 64, 111126.

10WA Pryor & K Stone (1993) Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite. Ann N Y Acad Sci 686, 1228.

11KK Griendling & GA FitzGerald (2003) Oxidative stress and cardiovascular injury: Part II: animal and human studies. Circulation 108, 20342040.

12RS Bruno & MG Traber (2006) Vitamin E biokinetics, oxidative stress and cigarette smoking. Pathophysiology 13, 143149.

13J Chávez , C Cano , A Souki , (2007) Effect of cigarette smoking on the oxidant/antioxidant balance in healthy subjects. Am J Ther 14, 189193.

14K Walsh & G Alexander (2000) Alcoholic liver disease. Postgrad Med J 76, 280286.

15T Zima , L Fialova , O Mestek , (2001) Oxidative stress, metabolism of ethanol and alcohol-related diseases. J Biomed Sci 8, 5970.

16OR Koch , G Pani , S Borrello , (2004) Oxidative stress and antioxidant defenses in ethanol-induced cell injury. Mol Aspects Med 25, 191198.

22Y Ito , M Minohara , M Otani , (1989) Effects of alcohol drinking and cigarette smoking on serum α- and β-carotene concentrations in healthy adults. Jpn J Hyg 44, 607614.

23N Tanabe , H Toyoshima , S Hayashi , (1992) Effects of smoking and drinking habits and vitamin A intake on serum concentration of β-carotene and retinol. Jpn J Hyg 47, 679687.

25Y Tsubono , S Tsugane & KF Gey (1996) Differential effects of cigarette smoking and alcohol consumption on the plasma levels of carotenoids in middle-aged Japanese men. Jpn J Cancer Res 87, 563569.

26A Fukao , Y Tsubono , M Kawamura , (1996) The independent association of smoking and drinking with serum β-carotene levels among males in Miyagi, Japan. Int J Epidemiol 25, 300306.

30P Galan , FE Viteri , S Bertrais , (2005) Serum concentrations of β-carotene, vitamins C and E, zinc and selenium are influenced by sex, age, diet, smoking status, alcohol consumption and corpulence in a general French adult population. Eur J Clin Nutr 59, 11811190.

31HE Gabriel , Z Liu , JW Crott , (2006) A comparison of carotenoids, retinoids, and tocopherols in the serum and buccal mucosa of chronic cigarette smokers versus nonsmokers. Cancer Epidemiol Biomarkers Prev 15, 993999.

32JG Bieri , ED Brown & JC Smith (1985) Determination of individual carotenoids in human plasma by high performance liquid chromatography. J Liq Chromatogr 8, 473484.

33M Sugiura , M Nakamura , Y Ikoma , (2005) High serum carotenoids are inversely associated with serum γ-glutamyltransferase in alcohol drinkers within normal liver function. J Epidemiol 15, 180186.

34K Wakai , I Egami , K Kato , (1999) A simple food frequency questionnaire for Japanese diet – Part I. Development of the questionnaire, and reproducibility and validity for food groups. J Epidemiol 9, 216226.

35I Egami , K Wakai , K Kato , (1999) A simple food frequency questionnaire for Japanese diet – Part II. Reproducibility and validity for nutrient intakes. J Epidemiol 9, 227234.

37M Yano , M Kato , Y Ikoma , (2005) Quantitation of carotenoids in raw and processed fruits in Japan. Food Sci Technol Res 11, 1318.

38K Aizawa & T Inakuma (2007) Quantitation of carotenoids in commonly consumed vegetables in Japan. Food Sci Technol Res 13, 247252.

39R Sandhir , S Subramanian & A Koul (2003) Long-term smoking and ethanol exposure accentuates oxidative stress in hearts of mice. Cardiovasc Toxicol 3, 135140.

40K Husain , BR Scott , SK Reddy , (2001) Chronic ethanol and nicotine interaction on rat tissue antioxidant defense system. Alcohol 25, 8997.

41W Hartwig , J Werner , E Ryschich , (2000) Cigarette smoke enhances ethanol-induced pancreatic injury. Pancreas 21, 272278.

43MA Leo & CS Lieber (1982) Hepatic vitamin A depletion in alcoholic liver injury. N Engl J Med 307, 597601.

44A During & EH Harrison (2004) Intestinal absorption and metabolism of carotenoids: insights from cell culture. Arch Biochem Biophys 430, 7788.

45J Chaudière & R Ferrari-Iliou (1999) Intracellular antioxidants: from chemical to biochemical mechanisms. Food Chem Toxicol 37, 949962.

47H Alho , P Sillanaukee , A Kalela , (2004) Alcohol misuse increases serum antibodies to oxidized LDL and C-reactive protein. Alcohol Alcohol 39, 312315.

48Y Yamaguchi , J Haginaka , S Morimoto , (2005) Facilitated nitration and oxidation of LDL in cigarette smokers. Eur J Clin Invest 35, 186193.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords: