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1WJ Broughton , G Hernández , M Blair , S Beebe , P Gepts & J Vanderleyden (2003) Beans (Phaseolus spp.) – model food legumes. Plant Soil 252, 55–128.
3DE Bowman (1945) Amylase inhibitor of navy bean. Science 102, 358–359.
5D Chokshi (2006) Toxicity studies of blockal, a dietary supplement containing Phase 2 starch neutralizer (Phase 2), a standardized extract of the common white kidney bean (Phaseolus vulgaris). Int J Toxicol 25, 361–371.
6P Layer , GL Carlson & EP DiMagno (1985) Partially purified white bean amylase inhibitor reduces starch digestion in vitro and inactivates intraduodenal amylase in humans. Gastroenterology 88, 1895–1902.
7P Layer , AR Zinsmeister & EP DiMagno (1986) Effects of decreasing intraluminal amylase activity on starch digestion and postprandial gastrointestinal function in humans. Gastroenterology 91, 41–48.
10BM Popkin & CM Doak (1998) The obesity epidemic is a worldwide phenomenon. Nutr Rev 56, 106–114.
12PT James , R Leach , E Kalamara & M Shayeghi (2001) The worldwide obesity epidemic. Obes Res 9, 2288–2338.
13AH Mokdad , ES Ford , BA Bowman , WH Dietz , F Vinicor , VS Bales & JS Marks (2003) Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA 289, 76–79.
17M Kusaba-Nakayama , M Ki , M Iwamoto , R Shibata , M Sato & K Imaizumi (2000) CM3, one of the wheat α-amylase inhibitor subunits, and binding of IgE in sera from Japanese with atopic dermatitis related to wheat. Food Chem Toxicol 38, 179–185.
18R Sanchez-Monge , G Garcia-Casado , C Lopez-Otin , A Armentia & G Salcedo (1997) Wheat flour peroxidase is a prominent allergen associated with baker's asthma. Clin Exp Allergy 27, 1130–1137.
19G Garcia-Casado , A Armentia , R Sanchez-Monge , JM Malpica & G Salcedo (1996) Rye flour allergens associated with baker's asthma. Correlation between in vivo and in vitro activities and comparison with their wheat and barley homologues. Clin Exp Allergy 26, 428–435.
20OL Franco , DJ Rigden , FR Melo & MF Grossi-de-Sa (2002) Plant α-amylase inhibitors and their interaction with insect α-amylases; structure, function and potential for crop protection. FEBS J 269, 397–412.
21AM Iguti & FM Lajolo (1991) Occurrence and purification of α-amylase isoinhibitors in bean (Phaseolus vulgaris L.) varieties. J Agric Food Chem 39, 2131–2136.
22M Ishimoto , K Suzuki , M Iwanaga , F Kikuchi & K Kitamura (1995) Variation of seed α-amylase inhibitors in the common bean. Theor Appl Genet 90, 425–429.
23M Ishimoto & K Kitamura (1991) Effect of absence of seed α-amylase inhibitor on the growth inhibitory activity to azuki bean weevil (Callosobruchus chinensis) in common bean (Phaseolus vulgaris L.). Jpn J Breed 41, 231–240.
24K Suzuki , M Ishimoto , F Kikuchi & K Kitamura (1993) Growth inhibitory effect of an α-amylase inhibitor from the wild common bean resistant to the Mexican bean weevil (Zabrotes subfasciatus). Jpn J Breed 43, 257–265.
25J Moreno , T Altabella & MJ Chrispeels (1990) Characterization of α-amylase inhibitor, a lectin-like protein in the seeds of Phaseolus vulgaris L. Plant Physiol 92, 703–709.
26J Moreno & MJ Chrispeels (1989) A lectin gene encodes the α-amylase inhibitor of the common bean. Proc Natl Acad Sci U S A 86, 7885–7889.
27JJ Pueyo , DC Hunt & MJ Chrispeels (1993) Activation of bean (Phaseolus vulgaris) α-amylase inhibitor requires proteolytic processing of the proprotein. Plant Physiol 101, 1341–1348.
28NM Young & RP Oomen (1992) Analysis of sequence variation among legume lectins. A ring of hypervariable residues forms the perimeter of the carbohydrate-binding site. J Mol Biol 228, 924–934.
29SC Lee , PL Gepts & JR Whitaker (2002) Protein structures of common bean (Phaseolus vulgaris) α-amylase inhibitors. J Agric Food Chem 50, 6618–6627.
30F Finardi-Filho , TE Mirkov & MJ Chrispeels (1996) A putative precursor protein in the evolution of the bean α-amylase inhibitor. Phytochemistry 43, 57–62.
31FMA Islam , KE Basford , RJ Redden , AV Gonzalez , PM Kroonenberg & S Beebe (2002) Genetic variability in cultivated common bean beyond the two major gene pools. Genet Resour Crop Evol 49, 271–283.
33F Sparvoli , C Lanave , A Santucci , R Bollini & L Lioi (2001) Lectin and lectin-related proteins in lima bean (Phaseolus lunatus L.) seeds: biochemical and evolutionary studies. Plant Mol Biol 45, 587–597.
34M Ishimoto , T Yamada & A Kaga (1999) Insecticidal activity of an α-amylase inhibitor-like protein resembling a putative precursor of α-amylase inhibitor in the common bean, Phaseolus vulgaris L. Biochim Biophys Acta 1432, 104–112.
35V Le Berre-Anton , V Nahoum , F Payan & P Rouge (2000) Molecular basis for the specific binding of different α-amylase inhibitors from Phaseolus vulgaris seeds to the active site of α-amylase. Plant Physiol Biochem 38, 657–665.
36A Santino , MG Daminati , A Vitale & R Bollini (1992) The α-amylase inhibitor of bean seed: two step proteolytic maturation in the protein storage vacuoles of the developing cotyledon. Physiol Plant 85, 425–432.
37NM Young , P Thibault , DC Watson & MJ Chrispeels (1999) Post-translational processing of two α-amylase inhibitors and an arcelin from the common bean, Phaseolus vulgaris. FEBS Lett 446, 203–206.
38M Santimone , R Koukiekolo , Y Moreau , V Le Berre , P Rouge , G Marchis-Mouren & V Desseaux (2004) Porcine pancreatic α-amylase inhibition by the kidney bean (Phaseolus vulgaris) inhibitor (α-AI1) and structural changes in the α-amylase inhibitor complex. Biochim Biophys Acta 1696, 181–190.
39H Higaki & H Yamaguchi (1994) Reconstitution of Phaseolus vulgaris α-amylase inhibitor from isolated subunits. Biosci Biotechnol Biochem 58, 5–8.
40S Sawada , Y Takeda & M Tashiro (2002) Primary structures of α- and β-subunits of α-amylase inhibitors from seeds of three cultivars of Phaseolus beans. J Protein Chem 21, 9–17.
41BF Gibbs & I Alli (1998) Characterization of a purified α-amylase inhibitor from white kidney beans (Phaseolus vulgaris). Food Res Int 31, 217–225.
42C Bompard-Gilles , P Rousseau , P Rouge & F Payan (1996) Substrate mimicry in the active center of a mammalian α-amylase: structural analysis of an enzyme-inhibitor complex. Structure 4, 1441–1452.
43I Kluh , M Horn , J Hyblova , J Hubert , L Doleckova-Maresova , Z Voburka , I Kudlikova , F Kocourek & M Mares (2005) Inhibitory specificity and insecticidal selectivity of α-amylase inhibitor from Phaseolus vulgaris. Phytochemistry 66, 31–39.
44K Kasahara , K Hayashi , T Arakawa , JS Philo , J Wen , S Hara & H Yamaguchi (1996) Complete sequence, subunit structure and complexes with pancreatic α-amylase of an α-amylase inhibitor from Phaseolus vulgaris white kidney beans. J Biochem 120, 177–183.
45R Koukiekolo , V Desseaux , Y Moreau , G Marchis-Mouren & M Santimone (2001) Mechanism of porcine pancreatic α-amylase inhibition of amylose and maltopentaose hydrolysis by α-, β-and γ-cyclodextrins. Eur J Biochem 268, 841–848.
46R Koukiekolo , V Le Berre-Anton , V Desseaux , Y Moreau , P Rouge , G Marchis-Mouren & M Santimone (1999) Mechanism of porcine pancreatic α-amylase inhibition of amylose and maltopentaose hydrolysis by kidney bean (Phaseolus vulgaris) inhibitor and comparison with that by acarbose. Eur J Biochem 265, 20–26.
47SC Lee & JR Whitaker (2000) The molecular weight of α-amylase inhibitior from white bean cv 858B (Phaseolus vulgaris L.) is 56 kDa, not 20 kDa. J Food Biochem 24, 55–67.
48V Le Berre-Anton , C Bompard-Gilles , F Payan & P Rouge (1997) Characterization and functional properties of the α-amylase inhibitor (α-AI) from kidney bean (Phaseolus vulgaris) seeds. Biochim Biophys Acta 1343, 31–40.
49FM Lajolo & F Finardi Filho (1985) Partial characterization of the amylase inhibitor of black beans (Phaseolus vulgaris), variety Rico 23. J Agric Food Chem 33, 132–138.
50M Kotaru , H Yoshikawa , T Ikeuchi , K Saito , K Iwami & F Ibuki (1987) An α-amylase inhibitor from cranberry bean (Phaseolus vulgaris): its specificity in inhibition of mammalian pancreatic α-amylases and formation of a complex with the porcine enzyme. J Nutr Sci Vitaminol (Tokyo) 33, 359–367.
51JR Powers & JR Whitaker (1977) Effect of several experimental parameters on combination of red kidney bean (Phaseolus vulgaris) α-amylase inhibitor with porcine pancreatic α-amylase. J Food Biochem 1, 239–260.
52A Valencia , AE Bustillo , GE Ossa & MJ Chrispeels (2000) α-Amylases of the coffee berry borer (Hypothenemus hampei) and their inhibition by two plant amylase inhibitors. Insect Biochem Mol Biol 30, 207–213.
53CL Collins , PJ Eason , FR Dunshea , TJV Higgins & RH King (2006) Starch but not protein digestibility is altered in pigs fed transgenic peas containing α-amylase inhibitor. J Sci Food Agric 86, 1894–1899.
54F Payan (2004) Structural basis for the inhibition of mammalian and insect α-amylases by plant protein inhibitors. Biochim Biophys Acta 1696, 171–180.
55V Nahoum , G Roux , V Anton , P Rougé , A Puigserver , H Bischoff , B Henrissat & F Payan (2000) Crystal structures of human pancreatic α-amylase in complex with carbohydrate and proteinaceous inhibitors. Biochem J 346, 201–208.
56R Maurus , A Begum , HH Kuo , A Racaza , S Numao , C Andersen , JW Tams , J Vind , CM Overall & SG Withers (2005) Structural and mechanistic studies of chloride induced activation of human pancreatic α-amylase. Protein Sci 14, 743–755.
57MF Ho & JR Whitaker (1993) Subunit structures and essential amino acid residues of white kidney bean (Phaseolus vulgaris) α-amylase inhibitors. J Food Biochem 17, 35–52.
58TE Mirkov , SV Evans , J Wahlstrom , L Gomez , NM Young & MJ Chrispeels (1995) Location of the active site of the bean α-amylase inhibitor and involvement of a Trp, Arg, Tyr triad. Glycobiology 5, 45–50.
59T Takahashi , S Hiramoto , S Wato , T Nishimoto , Y Wada , K Nagai & H Yamaguchi (1999) Identification of essential amino acid residues of an α-amylase inhibitor from Phaseolus vulgaris white kidney beans. J Biochem 126, 838–844.
60MCM Da Silva , MFG De Sá , MJ Chrispeels , RC Togawa & G Neshich (2000) Analysis of structural and physico-chemical parameters involved in the specificity of binding between α-amylases and their inhibitors. Protein Eng Des Sel 13, 167–177.
61M Qian (1997) Structure of a pancreatic α-amylase bound to a substrate analogue at 2·03 A resolution. Protein Sci 6, 2285–2296.
62ER Wilcox & JR Whitaker (1984) Some aspects of the mechanism of complexation of red kidney bean α-amylase inhibitor and α-amylase. Biochemistry 23, 1783–1791.
64M Boivin , AR Zinsmeister , VL Go & EP DiMagno (1987) Effect of a purified amylase inhibitor on carbohydrate metabolism after a mixed meal in healthy humans. Mayo Clin Proc 62, 249–255.
66NK Jain , M Boivin , AR Zinsmeister & EP DiMagno (1991) The ileum and carbohydrate-mediated feedback regulation of postprandial pancreaticobiliary secretion in normal humans. Pancreas 6, 495–505.
68GL Carlson , BU Li , P Bass & WA Olsen (1983) A bean α-amylase inhibitor formulation (starch blocker) is ineffective in man. Science 219, 393.
69GW Bo-Linn , CA Santa Ana , SG Morawski & JS Fordtran (1982) Starch blockers – their effect on calorie absorption from a high-starch meal. N Engl J Med 307, 1413–1416.
71DC Kilpatrick , C Green & PL Yap (1983) Lectin content of slimming pills. BMJ (Clin Res Ed) 286, 305.
73M Kotaru , K Iwami , HY Yeh & F Ibuki (1989) In vivo action of α-amylase inhibitor from cranberry bean (Phaseolus vulgaris) in rat small intestine. J Nutr Sci Vitaminol (Tokyo) 35, 579–588.
74H Yoshikawa , M Kotaru , C Tanaka , T Ikeuchi & M Kawabata (1999) Characterization of kintoki bean (Phaseolus vulgaris) α-amylase inhibitor: inhibitory activities against human salivary and porcine pancreatic α-amylases and activity changes by proteolytic digestion. J Nutr Sci Vitaminol (Tokyo) 45, 797–802.
75M Kotaru , K Iwami , HYU Yeh & F Ibuki (1991) Resistance of cranberry bean (Phaseolus vulgaris) α-amylase inhibitor to intraluminal digestion and its movement along rat gastrointestine: further investigation using a radioactive probe and specific antiserum. Food Chem 42, 29–37.
77KB Harikumar , AM Jesil , MC Sabu & R Kuttan (2005) A preliminary assessment of the acute and subchronic toxicity profile of Phase 2: an α-amylase inhibitor. Int J Toxicol 24, 95–102.
78T Itoh , N Kita , Y Kurokawa , M Kobayashi , F Horio & Y Furuichi (2004) Suppressive effect of a hot water extract of Adzuki beans (Vigna angularis) on hyperglycemia after sucrose loading in mice and diabetic rats. Biosci Biotechnol Biochem 68, 2421–2426.
84D Chokshi (2007) Subchronic oral toxicity of a standardized white kidney bean (Phaseolus vulgaris) extract in rats. Food Chem Toxicol 45, 32–40.
92M Higuchi , M Suga & K Iwai (1983) Participation of lectin in biological effects of raw winged bean seeds on rats. Agric Biol Chem 47, 1879–1886.
96J Carmalt , K Rosel , T Burns & E Janzen (2003) Suspected white kidney bean (Phaseolus vulgaris) toxicity in horses and cattle. Aust Vet J 81, 674–676.
100L Lioi , F Sparvoli & R Bollini (1999) Variation and genomic polymorphism of lectin-related proteins in Lima bean (Phaseolus lunatus L.) seeds. Genet Resour Crop Evol 46, 175–182.
101C Burbano , M Muzquiz , G Ayet , C Cuadrado & MM Pedrosa (1999) Evaluation of antinutritional factors of selected varieties of Phaseolus vulgaris. J Sci Food Agric 79, 1468–1472.
102VC Sgarbieri (1989) Nutritional values of cereal products, beans and starches. World Rev Nutr Diet 60, 132–198.
105SG Haralampu (2000) Resistant starch – a review of the physical properties and biological impact of RS3. Carbohydr Polymer 41, 285–292.
106AP Nugent (2005) Health properties of resistant starch. Nutr Bull 30, 27–54.
108RK Le Leu , IL Brown , Y Hu & GP Young (2003) Effect of resistant starch on genotoxin-induced apoptosis, colonic epithelium, and lumenal contents in rats. Carcinogenesis 24, 1347–1352.
114PR Holt , E Atillasoy , J Lindenbaum , SB Ho , JR Lupton , D McMahon & SF Moss (1996) Effects of acarbose on fecal nutrients, colonic pH, and short-chain fatty acids and rectal proliferative indices. Metabolism 45, 1179–1187.