Skip to main content
×
Home
    • Aa
    • Aa
  • Access
  • Cited by 76
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Adu-Afarwuah, Seth Lartey, Anna Okronipa, Harriet Ashorn, Per Zeilani, Mamane Baldiviez, Lacey M. Oaks, Brietta M. Vosti, Stephen and Dewey, Kathryn G. 2016. Impact of small-quantity lipid-based nutrient supplement on hemoglobin, iron status and biomarkers of inflammation in pregnant Ghanaian women. Maternal & Child Nutrition, p. n/a.


    Colarusso, Luca Serafini, Mauro Lagerros, Ylva Trolle Nyren, Olof La Vecchia, Carlo Rossi, Marta Ye, Weimin Tavani, Alessandra Adami, Hans-Olov Grotta, Alessandra and Bellocco, Rino 2016. Dietary Antioxidant Capacity and Risk of Stroke in a prospective cohort study of Swedish Men and Women. Nutrition,


    Henríquez-Sánchez, P. Sánchez-Villegas, A. Ruano-Rodríguez, C. Gea, A. Lamuela-Raventós, R. M. Estruch, R. Salas-Salvadó, J. Covas, M. I. Corella, D. Schröder, H. Gutiérrez-Bedmar, M. Santos-Lozano, J. M. Pintó, X. Arós, F. Fiol, M. Tresserra-Rimbau, A. Ros, E. Martínez-González, M. A. and Serra-Majem, L. 2016. Dietary total antioxidant capacity and mortality in the PREDIMED study. European Journal of Nutrition, Vol. 55, Issue. 1, p. 227.


    Iwasaki, Masanori Sato, Misuzu Yoshihara, Akihiro Ansai, Toshihiro and Miyazaki, Hideo 2016. Association between tooth loss and medical costs related to stroke in healthy older adults aged over 75 years in Japan. Geriatrics & Gerontology International, p. n/a.


    Vance, Terrence M. Wang, Ying Su, L. Joseph Fontham, Elizabeth T. H. Steck, Susan E. Arab, Lenore Bensen, Jeannette T. Mohler, James L. Chen, Ming-Hui and Chun, Ock K. 2016. Dietary Total Antioxidant Capacity is Inversely Associated with Prostate Cancer Aggressiveness in a Population-Based Study. Nutrition and Cancer, Vol. 68, Issue. 2, p. 214.


    Alissa, Eman M and Ferns, Gordon A 2015. Dietary Fruits and Vegetables and Cardiovascular Diseases Risk. Critical Reviews in Food Science and Nutrition, p. 00.


    Cheigh, Chan-Ick Yoo, Seo-Yeon Ko, Min-Jung Chang, Pahn-Shick and Chung, Myong-Soo 2015. Extraction characteristics of subcritical water depending on the number of hydroxyl group in flavonols. Food Chemistry, Vol. 168, p. 21.


    Corley, Janie Kyle, Janet A. M. Starr, John M. McNeill, Geraldine and Deary, Ian J. 2015. Dietary factors and biomarkers of systemic inflammation in older people: the Lothian Birth Cohort 1936. British Journal of Nutrition, Vol. 114, Issue. 07, p. 1088.


    Costanzo, Simona De Curtis, Amalia di Niro, Veronica Olivieri, Marco Morena, Mariarosaria De Filippo, Carlo Maria Caradonna, Eugenio Krogh, Vittorio Serafini, Mauro Pellegrini, Nicoletta Donati, Maria Benedetta de Gaetano, Giovanni and Iacoviello, Licia 2015. Postoperative atrial fibrillation and total dietary antioxidant capacity in patients undergoing cardiac surgery: The Polyphemus Observational Study. The Journal of Thoracic and Cardiovascular Surgery, Vol. 149, Issue. 4, p. 1175.


    Díaz-Rubio, M. Elena Pérez-Jiménez, Jara Martínez-Bartolomé, Miguel Ángel Álvarez, Inmaculada and Saura-Calixto, Fulgencio 2015. Regular Consumption of an Antioxidant-rich Juice Improves Oxidative Status and Causes Metabolome Changes in Healthy Adults. Plant Foods for Human Nutrition, Vol. 70, Issue. 1, p. 9.


    Kim, Sangmi Rimando, Joseph and Sandler, Dale P. 2015. Fruit and Vegetable Intake and Urinary Levels of Prostaglandin E2Metabolite in Postmenopausal Women. Nutrition and Cancer, Vol. 67, Issue. 4, p. 580.


    Narmaki, Elham Siassi, Fereydoun Fariba Koohdani, Qorbani, Mostafa Shiraseb, Farideh Ataie-Jafari, Asal and Sotoudeh, Gity 2015. Dietary diversity as a proxy measure of blood antioxidant status in women. Nutrition, Vol. 31, Issue. 5, p. 722.


    Pérez-Jiménez, Jara Elena Díaz-Rubio, M. and Saura-Calixto, Fulgencio 2015. Contribution of Macromolecular Antioxidants to Dietary Antioxidant Capacity: A Study in the Spanish Mediterranean Diet. Plant Foods for Human Nutrition, Vol. 70, Issue. 4, p. 365.


    Ross, Stephanie Maxine 2015. The Traditional Mediterranean Diet. Holistic Nursing Practice, p. 1.


    Wang, Peng Peng, Xiao Wei, Zuo-Fu Wei, Fu-Yao Wang, Wei Ma, Wei-Dong Yao, Li-Ping Fu, Yu-Jie and Zu, Yuan-Gang 2015. Geraniin exerts cytoprotective effect against cellular oxidative stress by upregulation of Nrf2-mediated antioxidant enzyme expression via PI3K/AKT and ERK1/2 pathway. Biochimica et Biophysica Acta (BBA) - General Subjects, Vol. 1850, Issue. 9, p. 1751.


    Eliaz, Isaac 2014. An Integrative Approach to Enhancing Cognition and Executive Brain Function: A Personal Perspective. Alternative and Complementary Therapies, Vol. 20, Issue. 1, p. 27.


    Kobayashi, S. Asakura, K. Suga, H. and Sasaki, S. 2014. Inverse association between dietary habits with high total antioxidant capacity and prevalence of frailty among elderly Japanese women: A multicenter cross-sectional study. The journal of nutrition, health & aging, Vol. 18, Issue. 9, p. 827.


    Kobayashi, S. Asakura, K. Suga, H. and Sasaki, S. 2014. Inverse association between dietary habits with high total antioxidant capacity and prevalence of frailty among elderly Japanese women: A multicenter cross-sectional study. The journal of nutrition, health & aging,


    Mahdad, Nadia Boukortt, Farida Ouda Benzian, Zakaria and Bouchenak, Malika 2014. Lifestyle advice follow-up improve glycemic control, redox and inflammatory status in patients with type 2 diabetes. Journal of Diabetes & Metabolic Disorders, Vol. 13, Issue. 1,


    Martínez, Joaquín Nieto, Gema and Ros, Gaspar 2014. Total antioxidant capacity of meat and meat products consumed in a reference ‘Spanish standard diet’. International Journal of Food Science & Technology, Vol. 49, Issue. 12, p. 2610.


    ×

Total antioxidant capacity of the diet is inversely and independently related to plasma concentration of high-sensitivity C-reactive protein in adult Italian subjects

  • Furio Brighenti (a1), Silvia Valtueña (a2), Nicoletta Pellegrini (a1), Diego Ardigò (a2), Daniele Del Rio (a1), Sara Salvatore (a1), PierMarco Piatti (a3), Mauro Serafini (a4) and Ivana Zavaroni (a2)
  • DOI: http://dx.doi.org/10.1079/BJN20051400
  • Published online: 01 March 2007
Abstract

Inflammation, a risk factor for cardiovascular disease, is associated with low plasma levels of antioxidant vitamins. In addition to vitamins, other antioxidants modulate the synthesis of inflammatory markers in vitro and contribute to the total antioxidant capacity (TAC) of a diet. However, the relationship between dietary TAC and markers of inflammation has never been evaluated in vivo. We investigated the relationship between dietary TAC and markers of systemic (high-sensitivity C-reactive protein (hs-CRP), leucocytes) and vascular (soluble intercellular cell adhesion molecule-1) inflammation in 243 non-diabetic subjects. General Linear Model (GLM) analysis showed a significant (P=0·005) inverse relationship between hs-CRP and quartiles of energy-adjusted dietary TAC, even when recognized modulating factors of inflammation, namely alcohol, fibre, vitamin C, α-tocopherol, β-carotene, BMI, waist circumference, HDL-cholesterol, hypertension, insulin sensitivity and plasma β-carotene, were included in the model as covariates (P=0·004). The relationship was stronger for subjects with hypertension (P=0·013 v. P=0·109 for normotensive individuals). Among dietary factors, TAC was significantly higher (5·3 (sd 3·0) v. 4·9 (sd 2·7) mmol Trolox/d; P=0·026) in subjects with low plasma hs-CRP (range: 0·0–4·1 mg/l) than in subjects with high plasma hs-CRP (range: 4·2–27·8 mg/l). We conclude that dietary TAC is inversely and independently correlated with plasma concentrations of hs-CRP and this could be one of the mechanisms explaining the protective effects against CVD of antioxidant-rich foods such as fruits, whole cereals and red wine. This could be of particular significance for subjects with high blood pressure.

    • Send article to Kindle

      To send this article to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Total antioxidant capacity of the diet is inversely and independently related to plasma concentration of high-sensitivity C-reactive protein in adult Italian subjects
      Your Kindle email address
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      Total antioxidant capacity of the diet is inversely and independently related to plasma concentration of high-sensitivity C-reactive protein in adult Italian subjects
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      Total antioxidant capacity of the diet is inversely and independently related to plasma concentration of high-sensitivity C-reactive protein in adult Italian subjects
      Available formats
      ×
Copyright
Corresponding author
*Corresponding author: Dr Silvia Valtueña, fax +39 0521 903271, email valtuena@libero.it
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

MA Albert , RJ Glynn & PM Ridker (2003) Alcohol consumption and plasma concentration of C-reactive protein. Circulation 107, 443447.

JM Carcamo , O Borquez-Ojeda & DW Golde (2002) Vitamin C inhibits granulocyte macrophage-colony-stimulating factor-induced signaling pathways. Blood 99, 32053212.

J Danesh , R Collins , P Appleby & R Peto (1998) Association of fibrinogen, C-reactive protein, albumin or leukocyte count with coronary heart disease: meta-analysis of prospective studies. JAMA 279, 14771482.

E Demerath , B Towne , J Blangero & RM Siervogel (2001) The relationship of soluble ICAM-1, VCAM-1, P-selectin and E-selectin to cardiovascular disease risk factors in healthy men and women. Ann Hum Biol 28, 664678.

ES Ford , S Liu , DM Mannino , WH Giles & SJ Smith (2003) C-reactive protein concentration and concentrations of blood vitamins, carotenoids, and selenium among United States adults. Eur J Clin Nutr 57, 11571163.

A Goudev , S Kyurkchiev , V Gergova , E Karshelova , D Georgiev , D Atar , I Kehayou & C Nacheu (2000) Reduced concentrations of soluble adhesion molecules after antioxidant supplementation in postmenopausal women with high cardiovascular risk profiles – a randomized double-blind study. Cardiology 94, 227232.

JM Graziano , JE Manson , LG Branch , GA Colditz , WC Willett & JE Buring (1995) A prospective study of consumption of carotenoids in fruits and vegetables and decreased cardiovascular mortality in the elderly. Ann Epidemiol 5, 255260.

TS Han , N Sattar , K Williams , C Gonzalez-Villalpando , ME Lean & SM Haffner (2002) Prospective study of C-reactive protein in relation to the development of diabetes and metabolic syndrome in the Mexico City Diabetes Study. Diabetes Care 25, 20162021.

A Imhof , M Froehlich , H Brenner , H Boeing , MB Peyps & W Koenig (2001) Effect of alcohol consumption on systemic markers of inflammation. Lancet 357, 763767.

DE King , BM Egan & ME Geesey (2003) Relation of dietary fat and fibre to elevation of C-reactive protein. Am J Cardiol 92, 13351339.

SB Kritchevsky , AJ Bush , M Pahor & MD Gross (2000) Serum carotenoids and markers of inflammation in nonsmokers. Am J Epidemiol 152, 10651071.

L Lind (2003) Circulating markers of inflammation and atherosclerosis. Atherosclerosis 169, 203214.

M Matsuda & RA DeFronzo (1999) Insulin sensitivity indices from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 22, 14621470.

F Parhami , ZT Fang , AM Fogelman , A Andalibi , MC Territo & JA Berliner (1993) Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine monophosphate. J Clin Invest 92, 471478.

N Pellegrini , Rio Del , Colombi D , Bianchi M B , F Brighenti (2003a) Application of the 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) radical cation assay to a flow injection system for the evaluation of antioxidant activity of some pure compounds and beverages. J Agric Food Chem 51, 260264.

M Saito , T Ishimitsu , J Minami , H Ono , M Ohrui & H Matsuoka (2003) Relations of plasma high-sensitivity C-reactive protein to traditional cardiovascular risk factors. Atherosclerosis 167, 7379.

S Salvini (1997) A food composition database for epidemiological studies in Italy. Cancer Lett 114, 299300.

C Sanchez-Moreno , JF Dashe , T Scott , D Thaler , MF Folstein & A Martin (2004) Decreased levels of plasma vitamin C and increased concentrations of inflammatory and oxidative stress markers after stroke. Stroke 35, 163168.

AR Tall (2004) C-reactive protein reassessed. N Engl J Med 350, 14501452.

B Van Dam , VW van Hinsbergh , CD Stehouwer , A Versiteilen , H Dekker , R Buytenhek , HM Princen & C Schalkunjk (2003) Vitamin E inhibits lipid peroxidation-induced adhesion molecules expression in endothelial cells and decreases soluble cell adhesion molecules in healthy subjects. Cardiovasc Res 57, 563571.

M Visser , LM Bouter , GM McQuillan , MH Wener & TB Harris (1999) Elevated C-reactive protein levels in overweight and obese adults. JAMA 282, 21312135.

SK Wattanapitayakul & JA Bauer (2001) Oxidative pathways in cardiovascular disease: roles, mechanisms, and therapeutic implications. Pharmacol Ther 89, 187206.

JT Willerson & PM Ridker (2004) Inflammation as a cardiovascular risk factor. Circulation 109, 210.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords: