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    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.
    Stumpf, David A. 1985. The inherited ataxias. Pediatric Neurology, Vol. 1, Issue. 3, p. 129.
    Rodrigue, F. Bélanger, F. van Gelder, N.M. and Barbeau, A. 1984. Platelet taurine content in Friedreich's disease. Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, Vol. 11, Issue. S4, p. 607.
    Barbeau, A. Patenaude, F. Nadon, G. Charbonneau, M. and Cloutier, T. 1982. A Possible Genetic Pattern of Taurine Urinary Excretion in Friedreich’s Ataxia. Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, Vol. 9, Issue. 02, p. 209.
    Barbeau, André 1982. Friedreich’s Disease 1982: Etiologic Hypotheses A personal analysis. Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, Vol. 9, Issue. 02, p. 243.
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The Beta-Amino Acid Transport System in Friedreich's Ataxia

  • S.B. Melançon (a1), B. Grignon (a1), E. Ledru (a1), G. Geoffroy (a1), M. Potier (a1), L. Dallaire (a1) and M. Vanasse (a1)...
Summary:

Taurine and β-amino uptake in cultured skin fibroblasts proceeds through at least two distinct amino acid transport systems. The predominant Bamino acid uptake system which we refer to as the “Beta” system, incorporates taurine in a proportion of 95%, β-alanine in a proportion of 80% and does not incorporate β-amino-isobutyric acid. A second transport system for β-alanine seems to be operative in cultured skin fibroblasts and this system shares the characteristics of system “L” for branched-chain and ringside neutral amino acids. Results of ion depletion experiments, metabolic inhibition by drugs and blocking agents and previous kinetic studies of taurine and β-alanine uptake in cultured skin fibroblasts failed to disclose any major difference in β-amino acid transport between control individuals and patients with Friedreich's ataxia.

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Copyright
COPYRIGHT: © Canadian Neurological Sciences Federation 1980
References
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