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Bilateral Central Ptosis in Acquired Immunodeficiency Syndrome

  • Jason J.S. Barton (a1), Randy H. Kardon (a1), Daniel Slagel (a2) and H. Stanley Thompson (a1)

Abstract:

A man with acquired immune deficiency syndrome suddenly developed bilateral complete ptosis and minor vertical gaze limitation. Magnetic resonance imaging revealed a lesion in the midbrain surrounding the sylvian aqueduct in addition to bilateral masses in the caudate nuclei. Pathologic examination showed that the caudate lesions were central nervous system lymphoma of B cell origin, but the midbrain lesion contained only signs of AIDS encephalopathy. The periaqueductal lesion involved the caudal central subnucleus and probably also the subnuclei of the superior and inferior recti of the oculomotor nuclear complex bilaterally.

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Copyright

Corresponding author

Division of Neurology, The Toronto Hospital, 399 Bathurst Street, Toronto, Ontario, Canada M5T 2S8

References

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1. Growdon, JH, Winkler, G, Wray, SH.Midbrain ptosis. A case with clinicopathologic correlation. Arch Neurol 1974; 30: 179181.
2. Meienberg, O, Mumenthaler, M, Karbowski, K.Quadriparesis and nuclear oculomotor palsy with total bilateral ptosis mimicking coma. Arch Neurol 1979; 36: 708710.
3. Conway, VH, Rozdilsky, B, Schneider, RJ, Sundaram, M.Isolated bilateral complete ptosis. Can J Opthalmol 1983; 18: 3740.
4. Dehaene, I, Dom, R, Marchau, M, Geens, K.Locked-in syndrome with bilateral ptosis: combination of bilateral horizontal pontine gaze paralysis and nuclear oculomotor nerve paralysis. J Neurol 1985; 232:366367.
5. Biller, J, Shapiro, R, Evans, LS, Haag, JR, Fine, M.Oculomotor nuclear complex infarction. Clinical and radiological correlation. Arch Neurol 1984; 41: 985987.
6. Bogousslavsky, J, Regli, F, Ghika, J, Hungerbühler, JRInternuclear ophthalmoplegia, prenuclear paresis of contralateral superior rectus, and bilateral ptosis. J Neurol 1983; 230: 197203.
7. Warwick, R.Representation of the extra-ocular muscles in the oculomotor nuclei of the monkey. J Comp Neurol 1953; 98: 449504.
8. Henn, V, Biittner-Ennever, JA, Hepp, K.The primate oculomotor system I. Motoneurons. Human Neurobiol 1982; 1: 7785.
9. Krohel, GB, Griffin, JF.Cortical blepharoptosis. Am J Opthalmol 1978; 85:632634.
10. Caplan, LR.Ptosis. J Neurol Neurosurg Psychiatry 1974; 37: 17.
11. Nutt, JG.Lid abnormalities secondary to cerebral hemisphere lesions. Ann Neurol 1977; 1: 149151.
12. Keane, JR, Zaias, B, Itabashi, HH.Levator-sparing oculomotor nerve palsy caused by a solitary midbrain metastasis. Arch Neurol 1984; 41:210212.
13. Elliott, RL.Encephalitis with ophthalmoplegia. Confin Neurol 1969; 31: 194197.
14. Stevenson, GC, Hoyt, WF.Metastasis to midbrain from mammary carcinoma. Cause of bilateral ptosis and ophthalmoplegia. JAMA 1963; 186:514516.
15. Zackon, DH, Sharpe, JA.Midbrain paresis of horizontal gaze. Ann Neurol 1984; 16: 495504.
16. Büttner-Ennever, JA, Acheson, JF, Büttner, U, Graham, EM, Leonard, TJK, et al. Ptosis and supranuclear downgaze paralysis. Neurology 1989; 39: 385389.
17. Iwanaga, K, Kinoshita, I, Nobuharu, O.Brainstem ptosis (midbrain ptosis) associated with mesencephalic hemorrhage. Rinsho Shinkeigaku 1990; 30: 793795.
18. Brasil-Neto, JP, Tosta, ED, Henriques, FG.Ptose palpebral bilateral com paralisia unilateral do olhar vertical para cima. Arquiv Neuro-psiquiatria 1986; 44: 8288.
19. Bril, V, Sharpes, JA, Ashby, P.Midbrain asterixis. Ann Neurol 1979; 6: 362364.
20. Kato, T, Hirano, A, Llenal, JF, Demlitzer, HM.Neuropathology of acquired immune deficiency syndrome (AIDS) in 53 autopsy cases with particular emphasis on microglial nodules and multinucleated giant cells. Acta Neuropathologica 1987; 73: 287297.
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Canadian Journal of Neurological Sciences
  • ISSN: 0317-1671
  • EISSN: 2057-0155
  • URL: /core/journals/canadian-journal-of-neurological-sciences
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