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    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.
    Blitz, Ari M. and Gujar, Sachin K. 2017. Limitations of Current Methodology for Assessment of Compression of the Optic Chiasm by Macroadenoma. Journal of Neuro-Ophthalmology, Vol. 37, Issue. 3, p. 239.
    Ryu, Won Hyung A. Starreveld, Yves Burton, Jodie M. Liu, Junjie and Costello, Fiona 2017. The Utility of Magnetic Resonance Imaging in Assessing Patients With Pituitary Tumors Compressing the Anterior Visual Pathway. Journal of Neuro-Ophthalmology, Vol. 37, Issue. 3, p. 230.
    Ellenberger, Carl 2016. Neuroimaging Part II. Vol. 136, Issue. , p. 887.
    Bauman, Craig A. Milligan, James D. Labreche, Tammy and Riva, John J. 2016. Nonfunctioning pituitary macroadenoma: a case report from the patient perspective. Chiropractic & Manual Therapies, Vol. 24, Issue. 1,
    Galland, Françoise Vantyghem, Marie-Christine Cazabat, Laure Boulin, Anne Cotton, François Bonneville, Jean-François Jouanneau, Emmanuel Vidal-Trécan, Gwénaelle and Chanson, Philippe 2015. Management of nonfunctioning pituitary incidentaloma. Annales d'Endocrinologie, Vol. 76, Issue. 3, p. 191.
    Sam, Amir H. Shah, Sachit Saleh, Keenan Joshi, Jay Roncaroli, Federico Robinson, Stephen Cox, Jeremy Martin, Niamh M. Mendoza, Nigel Meeran, Karim Mehta, Amrish and Dhillo, Waljit S. 2015. Clinical outcomes in patients with nonfunctioning pituitary adenomas managed conservatively. Clinical Endocrinology, Vol. 83, Issue. 6, p. 861.
    Kouamé, N. N’goan-Domoua, A.-M. Hué, A. N’gbesso, R.-D. and Kéita, A.K. 2012. Adénomes hypophysaires géants. Feuillets de Radiologie, Vol. 52, Issue. 4, p. 210.
    Chouinard, Philippe A. Striemer, Christopher L. Ryu, Won Hyung A. Sperandio, Irene Goodale, Melvyn A. Nicolle, David A. Rotenberg, Brian and Duggal, Neil 2012. Retinotopic organization of the visual cortex before and after decompression of the optic chiasm in a patient with pituitary macroadenoma. Journal of Neurosurgery, Vol. 117, Issue. 2, p. 218.
    Pereira, Alberto M. and Biermasz, Nienke R. 2012. Treatment of nonfunctioning pituitary adenomas: What were the contributions of the last 10years? A critical view. Annales d'Endocrinologie, Vol. 73, Issue. 2, p. 111.
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Conservative Management of Pituitary Macroadenoma Contacting the Optic Apparatus

  • Won Hyung A. Ryu (a1), Samantha Tam (a2), Brian Rotenberg (a3), Mohamed Ahmed Labib (a4), Donald Lee (a5), David A. Nicolle (a6), Stan Van Uum (a7) and Neil Duggal (a4)...
Abstract
Objectives:

To describe the tumor characteristics and visual function in conservatively managed patients with non-functioning pituitary macroadenoma (NFMA) that contacted/compressed the visual pathway.

 Design:

Retrospective case-series.

 Setting:

Tertiary-care academic institution.

 Participants:

Six patients with diagnosis of NFMA.

 Main Outcome:

Visual function and radiological characteristics of the optic apparatus and pituitary tumor.

 Results:

All patients had radiological evidence of optic apparatus compression but only one had visual field defect at the initial presentation. While two of the six patients developed visual field changes during follow-up (41±34.8 months), the patient with visual field defect at the time of diagnosis improved to normal vision.

 Conclusions:

Select NFMAs that contact the optic apparatus, without visual dysfunction, may be managed with close ophthalmological and radiographic monitoring, depending on tumor and imaging characteristics. This may be of particular relevance in patients considered to have a high peri-operative risk, such as advanced age or significant co-morbidities.
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Copyright
COPYRIGHT: © The Canadian Journal of Neurological 2010
Corresponding author
Department of Clinical Neurological Sciences, (Division of Neurosurgery), University of Western Ontario, 339 Windermere Road, London, Ontario, N6A 5A5, Canada
References
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Canadian Journal of Neurological Sciences
  • ISSN: 0317-1671
  • EISSN: 2057-0155
  • URL: /core/journals/canadian-journal-of-neurological-sciences
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