Skip to main content Accessibility help

Anatomic correction of congenitally corrected transposition and its close cousins

  • Edward L. Bove (a1), Richard G. Ohye (a1), Eric J. Devaney (a1), Hiromi Kurosawa (a2), Toshiharu Shin'oka (a2), Aki Ikeda (a2) and Toshio Nakanishi (a2)...


The congenital cardiac malformation characterized by discordant connections between the atriums and ventricles, as well as those between the ventricles and the arterial trunks, has been given many names. The terms atrioventricular discordance, l-transposition of the great arteries, ventricular inversion, and congenitally corrected transposition have all been used. Regardless of terminology, this complex congenital anomaly has only recently been studied to analyze the long-term effects of its natural history and outcomes following traditional surgical repair of the associated malformations which serve to uncorrect the circulatory pathways. As more patients survive into adulthood, the effects of this condition are now better understood, and the surgical approaches used in the past are being re-examined in light of longer-term follow up.


Corresponding author

Correspondence to: Edward L. Bove MD, Director, Pediatric Cardiovascular Surgery, Congenital Heart Center, F7830 Mott Children's Hospital, 1500 East Medical Center Drive, Ann Arbor, Michigan 48109, United States of America. Tel:+734 936 4980; Fax:+734 763 7353; E-mail:


Hide All


Allwork S, Bentall HH, Becker AE, et al. Congenitally corrected transposition of the great arteries. Morphologic study of 32 cases. Am J Cardiol 1976; 38: 910923.
Becker AE, Anderson RH. Conditions with discordant atrioventricular connections – Anatomy and conductive tissues. In: Anderson RH, Shinebourne EA (eds). Pediatric Cardiology 1977, Churchill Livingstone, London, 1978, p 184.
Kurosawa H, Imai Y, Becker AE. Congenitally corrected transposition with normally positioned atria, straddling mitral valve, and isolated posterior atrioventricular node bundle. J Thorac Cardiovasc Surg 1990; 99: 312313.
Mahle WT, Marx GR, Anderson RH. Anatomy and echocardiography of discordant atrioventricular connections. Cardiol Young, 2006; 16: this suppl.
Anderson RH, Becker AE, Arnold R, Wilkinson JL. The conducting tissues in congenitally corrected transposition. Circulation 1974; 50: 911923.
Uher V. Zur pathologie des reizleietungssystem bei congenital herzanomalien. Frank Z Pathol 1936; 347365.
Monckeberg JG. Zur entwicklungsgeschicte des atrioventricular-systems. Verhandl d Deutsch path Gesellsch 1913; 18: 228249.
Hosseinpour AR, McCarthy KP, Griselli M, Sethia B, Ho SY. Congenitally corrected transposition: size of the pulmonary trunk and septal malalignment. AnnThor Surg 2004; 77: 21632166.
Lundstrom U, Bull C, Wyse RK, Somerville J. The natural and “unnatural” history of congenitally corrected transposition. Am J Cardiol 1990; 65: 12221229.
Graham Jr TP, Bernard YD, Mellen BG, et al. Long-term outcome in congenitally corrected transposition of the great arteries: a multi-institutional study. J Am Coll Cardiol 2000; 36: 255261.
Prieto LR, Hordof AJ, Secic M, Rosenbaum MS, Gersony WM. Progressive tricuspid valve disease in patients with congenitally corrected transposition of the great arteries. Circulation 1998; 98: 9971005.
Connelly MS, Liu PP, Williams WG, Webb GD, Robertson P, McLaughlin PR. Congenitally corrected transposition of the great arteries in the adult: functional status and complications. J Am Coll Cardiol 1996; 27: 12381243.
Presbitero P, Somerville J, Rabajoli F, Stone S, Conte MR. Corrected transposition of the great arteries without associated defects in adult patients: clinical profile and follow up. Br Heart J 1995; 74: 5759.
van Son JA, Danielson GK, Huhta JC, et al. Late results of systemic atrioventricular valve replacement in corrected transposition. J Thorac Cardiovasc Surg 1995; 109: 642652.
Termignon JL, Leca F, Vouhe PR, et al. “Classic” repair of congenitally corrected transposition and ventricular septal defect. Ann Thorac Surg 1996; 62: 199206.
Hraska V, Duncan BW, Mayer Jr JE, et al. Long-term outcome of surgically treated patients with corrected transposition of the great arteries. J Thorac Cardiovasc Surg 2005; 129: 182191.
de Leval MR, Bastos P, Stark J, Taylor JFN, Macartney FJ, Anderson RH. Surgical technique to reduce the risks of heart block following closure of ventricular septal defect in atrioventricular discordance. J Thorac Cardiovasc Surg 1979; 78: 515.
Bove EL. Congenitally corrected transposition of the great arteries: options for biventricular repair. Prog Ped Cardiol 1999; 10: 4549.
Szufladowicz M, Horvath P, de Leval M, Elliott M, Wyse R, Stark J. Intracardiac repair of lesions associated with atrioventricular discordance. Eur J Cardiothorac Surg 1996; 10: 443448.
Biliciler-Denktas G, Feldt RH, Connolly HM, Weaver AL, Puga FJ, Danielson GK. Early and late results of operations for defects associated with corrected transposition and other anomalies with atrioventricular discordance in a pediatric population. J Thorac Cardiovasc Surg 2001; 122: 234241.
Imai Y, Seo K, Aoki M, Shin'oka T, Hiramatsu K, Ohta A. Double-Switch operation for congenitally corrected transposition. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2001; 4: 1633.
Devaney EJ, Charpie JR, Ohye RG, Bove EL. Combined arterial switch and Senning operation for congenitally corrected transposition of the great Arteries: patient selection and intermediate-term results. J Thorac Cardiovasc Surg 2003; 125: 500507.
Imamura M, Drummond-Webb JJ, Murphy Jr DJ, et al. Results of the double switch operation in the current era. Ann Thorac Surg 2000; 70: 100105.
Yamagishi M, Imai Y, Hoshino S, et al. Anatomic correction of atrioventricular discordance. J Thorac Cardiovasc Surg 1993; 105: 10671076.
Karl TR, Weintraub RG, Brizard CP, Cochrane AD, Mee RB. Senning plus arterial switch operation for discordant (congenitally corrected) transposition. Ann Thorac Surg 1997; 64: 495502.
Yagihara T, Kishimoto H, Isobe F, et al. Double switch operation in cardiac anomalies with atrioventricular and ventriculoarterial discordance. J Thorac Cardiovasc Surg 1994; 107: 351358.
Ilbawi MN, Ocampo CB, Allen BS, et al. Intermediate results of the anatomic repair for congenitally corrected transposition. Ann Thorac Surg 2002; 73: 594599.
Sharma R, Bhan A, Juneja R, Kothari SS, Saxena A, Venugopal P. Double switch for congenitally corrected transposition of the great arteries. Eur J Cardiothorac Surg 1999; 15: 276281.
Tanaka K, Kurosawa H, Morita K, Nomura K. Double switch with reversed Patrick-McGoon for corrected transposition of the great arteries with double outlet right ventricle. Jpn J Thorac Cardiovasc Surg 2004; 52: 300304.



Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed