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Cortical hyperostosis as a side-effect of prolonged use of prostaglandins

Published online by Cambridge University Press:  01 October 2015

Natalia Rivero Jiménez ,
Montserrat Bret-Zurita  and
Luis García-Guereta Silva
Natalia Rivero Jiménez*
Affiliation:
Department of Pediatric Cardiology, La Paz Hospital, Madrid, Spain
Montserrat Bret-Zurita
Affiliation:
Department of Pediatric Radiology, La Paz Hospital, Madrid, Spain
Luis García-Guereta Silva
Affiliation:
Department of Pediatric Cardiology, La Paz Hospital, Madrid, Spain
*
Correspondence to: N. R. Jiménez, Department of Pediatric Cardiology, La Paz Hospital, 261 Paseo de la Castellana, Madrid 28046, Spain. Tel: +61 990 5837; Fax: 91 727 70 50; E-mail: natalia17rj@hotmail.com
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Abstract

Cortical hyperostosis is a very uncommon side-effect of prolonged prostaglandin therapy with distinctive radiological signs that may be accompanied by painful swelling of the limbs and responds rapidly to withdrawal of therapy.

Keywords

Cortical hyperostosisprostaglandin E1side-effectsCHDductus arteriosus
Type
Images in Congenital Cardiac Disease
Information
Cardiology in the Young , Volume 26 , Issue 1 , January 2016 , pp. 149 - 150
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Copyright
© Cambridge University Press 2015 

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References

1. Jorgensen, HR, Svanholm, H, Host, A. Bone formation induced in an infant by systemic prostaglandin E2 administration. Acta Orthop Scand 1988; 59: 464–466.CrossRefGoogle Scholar