1.Bishop, SP. The myocardial cell: normal growth, cardiac hypertrophy and response to injury. Toxicol Pathol 1990; 18: 438–453.
2.Saiki, Y, Konig, A, Waddell, J, Rebeyka, IM. Hemodynamic alteration by fetal surgery accelerates myocyte proliferation in fetal guinea pig hearts. Surgery 1997; 122: 412–419.
3.Clark, EB, Hu, N, Frommelt, P, Vandekieft, GK, Dummett, JL, Tomanek, RJ. Effect of increased pressure on ventricular growth in stage 21 chick embryos. Am J Physiol 1989; 257: H55–H61.
4.Sedmera, D, Hu, N, Weiss, KM, Keller, BB, Denslow, S, Thompson, RP. Cellular changes in experimental left heart hypoplasia. Anat Rec 2002; 267: 137–145.
5.Hefti, MA, Harder, BA, Eppenberger, HM, Schaub, MC. Signaling pathways in cardiac myocyte hypertrophy. J Mol Cell Cardiol 1997; 29: 2873–2892.
6.Pasumarthi, KB, Field, LJ. Cardiomyocyte cell cycle regulation. Circ Res 2002; 90: 1044–1054.
7.Sylven, C. Angiogenic gene therapy. Drugs Today (Barc) 2002; 38: 819–827.
8.Stern, CD. The chick; a great model system becomes even greater. Dev Cell 2005; 8: 9–17.
9.Antin, PB, Fallon, JF, Schoenwolf, GC. The chick embryo rules (still)! Dev Dyn 2004; 229: 413.
10.Sedmera, D, Pexieder, T, Rychterova, V, Hu, N, Clark, EB. Remodeling of chick embryonic ventricular myoarchitecture under experimentally changed loading conditions. Anat Rec 1999; 254: 238–252.
11.Tobita, K, Keller, BB. Right and left ventricular wall deformation patterns in normal and left heart hypoplasia chick embryos. Am J Physiol Heart Circ Physiol 2000; 279: H959–969.
12.Sedmera, D, Cook, AC, Shirali, G, McQuinn, TC. Current issues and perspectives in hypoplasia of the left heart. Cardiol Young 2005; 15: 56–72.
13.Itoh, N, Ornitz, DM. Evolution of the Fgf and Fgfr gene families. Trends Genet 2004; 20: 563–569.
14.Ornitz, DM. FGFs, heparan sulfate and FGFRs: complex interactions essential for development. Bioessays 2000; 22: 108–112.
15.Eswarakumar, VP, Lax, I, Schlessinger, J. Cellular signaling by fibroblast growth factor receptors. Cytokine Growth Factor Rev 2005; 16: 139–149.
16.Lynch, P, Lee, TC, Fallavollita, JA, Canty, JM Jr, Suzuki, G. Intracoronary administration of AdvFGF-5 (fibroblast growth factor-5) ameliorates left ventricular dysfunction and prevents myocyte loss in swine with developing collaterals and ischemic cardiomyopathy. Circulation 2007; 116: I71–I76.
17.Suzuki, G, Lee, TC, Fallavollita, JA, Canty, JM Jr. Adenoviral gene transfer of FGF-5 to hibernating myocardium improves function and stimulates myocytes to hypertrophy and reenter the cell cycle. Circ Res 2005; 96: 767–775.
18.Demiroglu, A, Steer, EJ, Heath, C, et al. The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins. Blood 2001; 98: 3778–3783.
19.Lee, PL, Johnson, DE, Cousens, LS, Fried, VA, Williams, LT. Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor. Science 1989; 245: 57–60.
20.Powers, CJ, McLeskey, SW, Wellstein, A. Fibroblast growth factors, their receptors and signaling. Endocr Relat Cancer 2000; 7: 165–197.
21.Detillieux, KA, Sheikh, F, Kardami, E, Cattini, PA. Biological activities of fibroblast growth factor-2 in the adult myocardium. Cardiovasc Res 2003; 57: 8–19.
22.Speir, E, Tanner, V, Gonzalez, AM, Farris, J, Baird, A, Casscells, W. Acidic and basic fibroblast growth factors in adult rat heart myocytes. Localization, regulation in culture, and effects on DNA synthesis. Circ Res 1992; 71: 251–259.
23.Lavine, KJ, Yu, K, White, AC, et al. Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo. Dev Cell 2005; 8: 85–95.
24.Colvin, JS, Feldman, B, Nadeau, JH, Goldfarb, M, Ornitz, DM. Genomic organization and embryonic expression of the mouse fibroblast growth factor 9 gene. Dev Dyn 1999; 216: 72–88.
25.Pennisi, DJ, Ballard, VL, Mikawa, T. Epicardium is required for the full rate of myocyte proliferation and levels of expression of myocyte mitogenic factors FGF2 and its receptor, FGFR-1, but not for transmural myocardial patterning in the embryonic chick heart. Dev Dyn 2003; 228: 161–172.
26.Parlow, MH, Bolender, DL, Kokan-Moore, NP, Lough, J. Localization of bFGF-like proteins as punctate inclusions in the preseptation myocardium of the chicken embryo. Dev Biol 1991; 146: 139–147.
27.Sugi, Y, Sasse, J, Lough, J. Inhibition of precardiac mesoderm cell proliferation by antisense oligodeoxynucleotide complementary to fibroblast growth factor-2 (FGF- 2). Dev Biol 1993; 157: 28–37.
28.Jimenez, SK, Sheikh, F, Jin, Y, et al. Transcriptional regulation of FGF-2 gene expression in cardiac myocytes. Cardiovasc Res 2004; 62: 548–557.
29.Sheikh, F, Hirst, CJ, Jin, Y, et al. Inhibition of TGFbeta signaling potentiates the FGF-2-induced stimulation of cardiomyocyte DNA synthesis. Cardiovasc Res 2004; 64: 516–525.
30.Velez, C, Aranega, AE, Melguizo, C, Fernandez, JE, Prados, J, Aranega, A. Modulation of contractile protein troponin-T in chick myocardial cells by basic fibroblast growth factor and platelet-derived growth factor during development. J Cardiovasc Pharmacol 1994; 24: 906–913.
31.Franciosi, JP, Bolender, DL, Lough, J, Kolesari, GL. FGF-2-induced imbalance in early embryonic heart cell proliferation: a potential cause of late cardiovascular anomalies. Teratology 2000; 62: 189–194.
32.Mima, T, Ueno, H, Fischman, DA, Williams, LT, Mikawa, T. Fibroblast growth factor receptor is required for in vivo cardiac myocyte proliferation at early embryonic stages of heart development. Proc Natl Acad Sci U S A 1995; 92: 467–471.
33.Mikawa, T. Retroviral targeting of FGF and FGFR in cardiomyocytes and coronary vascular cells during heart development. Ann N Y Acad Sci 1995; 752: 506–516.
34.Kardami, E, Liu, L, Kishore, S, Pasumarthi, B, Doble, BW, Cattini, PA. Regulation of basic fibroblast growth factor (bFGF) and FGF receptors in the heart. Ann N Y Acad Sci 1995; 752: 353–369.
35.Sheikh, F, Fandrich, RR, Kardami, E, Cattini, PA. Overexpression of long or short FGFR-1 results in FGF-2-mediated proliferation in neonatal cardiac myocyte cultures. Cardiovasc Res 1999; 42: 696–705.
36.Hamburger, V, Hamilton, HL. A series of normal stages in the development of the chick embryo. J Morphol 1951; 88: 49–92.
37.Nesbit, M, Nesbit, HK, Bennett, J, et al. Basic fibroblast growth factor induces a transformed phenotype in normal human melanocytes. Oncogene 1999; 18: 6469–6476.
38.Kajstura, J, Rota, M, Whang, B, et al. Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion. Circ Res 2005; 96: 127–137.
39.Zhou, M, Sutliff, RL, Paul, RJ, et al. Fibroblast growth factor 2 control of vascular tone. Nat Med 1998; 4: 201–207.
40.Kang, J, Gu, Y, Li, P, Johnson, BL, Sucov, HM, Thomas, PS. PDGF-A as an epicardial mitogen during heart development. Dev Dyn 2008; 237: 692–701.
41.Lavine, KJ, Schmid, GJ, Smith, CS, Ornitz, DM. Novel tool to suppress cell proliferation in vivo demonstrates that myocardial and coronary vascular growth represent distinct developmental programs. Dev Dyn 2008; 237: 713–724.
42.Liechty, KW, Nesbit, M, Herlyn, M, Radu, A, Adzick, NS, Crombleholme, TM. Adenoviral-mediated overexpression of platelet-derived growth factor-B corrects ischemic impaired wound healing. J Invest Dermatol 1999; 113: 375–383.
43.Donahue, JK, Heldman, AW, Fraser, H, et al. Focal modification of electrical conduction in the heart by viral gene transfer. Nat Med 2000; 6: 1395–1398.
44.Christensen, G, Minamisawa, S, Gruber, PJ, Wang, Y, Chien, KR. High-efficiency, long-term cardiac expression of foreign genes in living mouse embryos and neonates. Circulation 2000; 101: 178–184.
45.Cheng, G, Litchenberg, WH, Cole, GJ, Mikawa, T, Thompson, RP, Gourdie, RG. Development of the cardiac conduction system involves recruitment within a multipotent cardiomyogenic lineage. Development 1999; 126: 5041–5049.
46.Orlic, D, Kajstura, J, Chimenti, S, et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001; 410: 701–705.
47.Zhang, N, Mustin, D, Reardon, W, et al. Blood-borne stem cells differentiate into vascular and cardiac lineages during normal development. Stem Cells Dev 2006; 15: 17–28.
48.Linke, A, Muller, P, Nurzynska, D, et al. Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function. Proc Natl Acad Sci U S A 2005; 102: 8966–8971.
49.Tobita, K, Garrison, JB, Li, JJ, Tinney, JP, Keller, BB. Three-dimensional myofiber architecture of the embryonic left ventricle during normal development and altered mechanical loads. Anat Rec A Discov Mol Cell Evol Biol 2005; 283: 193–201.
50.Dow, JK, deVere White, RW. Fibroblast growth factor 2: its structure and property, paracrine function, tumor angiogenesis, and prostate-related mitogenic and oncogenic functions. Urology 2000; 55: 800–806.
51.Kumar-Singh, S, Weyler, J, Martin, MJ, Vermeulen, PB, Van Marck, E. Angiogenic cytokines in mesothelioma: a study of VEGF, FGF-1 and -2, and TGF beta expression. J Pathol 1999; 189: 72–78.
52.deAlmeida, A, McQuinn, T, Sedmera, D. Increased ventricular preload is compensated by myocyte proliferation in normal and hypoplastic fetal chick left ventricle. Circ Res 2007; 100: 1363–1370.