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    Hsu, Daphne T. 2015. Challenges of designing multicenter trials in pediatric heart failure. Progress in Pediatric Cardiology, Vol. 39, Issue. 1, p. 49.


Intensive care management of neonates with d-transposition of the great arteries and common arterial trunk

  • Pirouz Shamszad (a1), Ryan A. Moore (a1), Nancy Ghanayem (a2) and David S. Cooper (a1)
  • DOI:
  • Published online: 18 January 2013

Although mortality rates for patients with d-transposition of the great arteries remain quite low, these patients have a unique circulation that requires careful management in the peri-operative period. Despite the improved mortality for patients with common arterial trunk, the course in the intensive care unit is remarkable for significant morbidity and utilisation of significant resources. Pre-operative patient management focuses on balancing competing circulations, pulmonary and systemic, which exist in parallel rather than in series, as in the normal circulation. Post-operative patient management in both lesions focuses on optimising systemic output, respiratory status, and mitigating the effects of cardiopulmonary bypass. In this article, we review pre- and post-operative intensive care management in neonates with d-transposition of the great arteries and common arterial trunk.

Corresponding author
Correspondence to: Dr D. S. Cooper, MD, MPH, The Heart Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine, 3333 Burnet Avenue, MLC 2003, Cincinnati, Ohio 45229, United States of America. Tel: 513 803 1801; Fax: 513 636 3952; E-mail:
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Cardiology in the Young
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