Skip to main content
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 5
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Hascoët, Sebastien Baruteau, Alban Jalal, Zakaria Mauri, Lucia Acar, Philippe Elbaz, Meyer Boudjemline, Younes and Fraisse, Alain 2014. Stents in paediatric and adult congenital interventional cardiac catheterization. Archives of Cardiovascular Diseases, Vol. 107, Issue. 8-9, p. 462.

    Hayes, Nicholas Podnar, Tomaž and Qureshi, Shakeel 2014. Collapse of the advanta V12 large diameter covered stent following implantation for aortic coarctation. Catheterization and Cardiovascular Interventions, Vol. 83, Issue. 1, p. 109.

    Novosel, Luka Perkov, Dražen Dobrota, Savko Ćorić, Vedran and Padovan, Ranka Štern 2014. Aortic Coarctation Associated with Aortic Valve Stenosis and Mitral Regurgitation in an Adult Patient: A Two-Stage Approach Using a Large-Diameter Stent Graft. Annals of Vascular Surgery, Vol. 28, Issue. 2, p. 494.e9.

    Vanagt, Ward Y. Cools, Björn Boshoff, Derize E. Frerich, Stefan Heying, Ruth Troost, Els Louw, Jacoba Eyskens, Benedicte Budts, Werner and Gewillig, Marc 2014. Use of covered Cheatham-Platinum stents in congenital heart disease. International Journal of Cardiology, Vol. 175, Issue. 1, p. 102.

    OHNO, NAOKI CHATURVEDI, RAJIV LEE, KYONG-JIN HORLICK, ERIC M. OSTEN, MARK D. and BENSON, LEE N. 2013. Experience With the Atrium Advanta Covered Stent for Aortic Obstruction. Journal of Interventional Cardiology, Vol. 26, Issue. 4, p. 411.


Large-diameter graft-stent (Advanta V12) implantation in various locations: early results

  • Dietmar Schranz (a1), Christian Jux (a1), Melanie Vogel (a1), Jürgen Bauer (a1), Hakan Akintürk (a1) and Klaus Valeske (a1)
  • DOI:
  • Published online: 27 October 2010

Transcatheter stent placement carries the risk of cardiovascular aneurysm or rupture. Covered stent implantation reduces these risks. The recently marketed Advanta V12 large-diameter-covered stent is pre-mounted and requires 9 (8)-11 Fr delivery systems. The aim was to report on the early results of the treatment of various cardiovascular obstructions by the implantation of a new polytetrafluoroethylene-covered stent (V12).


Graft stents on balloons with a diameter (12, 14, 16 millimetres) sufficient to anchor the stent in various obstructions (congenital aortic coarctation, n = 5; obstruction after ascending aorta repair, n = 2; pulmonary arteries, n = 5; inferior caval vein, n = 1; atretic superior caval vein, n = 1; pulmonary vein obstruction, n = 1; and right ventricular outflow tract, n = 1) were implanted using the smallest available delivery system. Secondary dilation with larger-diameter balloons was performed when the residual pressure was gradient, the stent-vessel wall relationship or stent re-coiling due to different reasons needed a re-intervention by pure ballooning or second stent placement.


All 16 patients aged 5–46 years underwent V12 implantation. The variability of the treated lesions and the need for additional interventions were responsible for large ranges in fluoroscopy time between 7.3 to 48.2 minutes (median 17.3). Considering the additional procedures, the V12 stent achieved the desired result in all cases. There were no major complications. At short-term median follow-up of 2 months, all patients are alive and well with no evidence of stent failing.


These initial results show that the covered Advanta V12 large-diameter stent is safe and effective in the immediate treatment of various cardiovascular obstructions. Long-term follow-up is required.

Corresponding author
Correspondence to: Professor Dr D. Schranz, Pediatric Heart Center, Justus-Liebig University, Feulgenstrasse 12, 35385 Giessen, Germany. Tel: 049 641 9943461 Fax: 049 641 9943469; E-mail:
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1.MP O’Laughlin , SB Perry , JE lock , CE Mullins . Use of endovascular stents in congenital heart disease. Circulation 1991; 83: 19231939.

2.R Fogelman , D Nykanen , JF Smallhorn , Endovascular stents in the pulmonary circulation: clinical impact on management and medium-term follow-up. Circulation 1995; 92: 881885.

3.MR Ebeid , LR Prieto , LA Latson . Use of balloon-expandable stents for coarctation of the aorta: initial results and intermediate-term follow-up. J Am Coll Cardiol 1997; 30: 18471852.

4.C Ovaert , CA Calderone , BW McCrindle , Endovascular stent implantation for the management of postoperative right ventricular outflow tract obstruction: clinical efficacy. J Thorac Cardiovasc Surg 1999; 118: 886893.

5.F Ing . Stents: what’s available to the pediatric interventional cardiologist’s. Catheter Cardiovasc Interv 2002; 57: 374386.

6.J Kreutzer , JJ Rome . Open-cell design stents in congenital heart disease: a comparison of IntraStent vs Palmaz stents. Catheter Cardiovasc Interv 2002; 56: 400409.

7.H Hussein , K Walsh . First in man use of the Advanta trademark V12 e PTFE-coated stent in aortic coarctation. Catheter Cardiovasc Interv 2009; 74: 101102.

8.E Bruckheimer , E Birk , R Santiago , T Dagan , C Esteves , CAC Pedra . Coarctation of the aorta treated with the Advanta V12 large diameter stent: acute results. Catheter Cardiovasc Interv 2010; 75: 402406.

9.R Bokenkamp , N Blom , D deWolf , Intraoperative stenting of pulmonary arteries. Eur J Cardiothorac Surg 2005; 27: 544547.

10.H Tomita , S Yazaki , K Kimura , Potential goals for the dimensions of the pulmonary arteries and aorta with stenting after the Fontan operation. Catheter Cardiovasc Interv 2002; 56: 246253.

11.EA Bacha , AC Marshall , DB McElhinney , PJ del Nido . Expanding the hybrid concept in congenital heart surgery. Semin Thorac Cardiovasc Surg pediatr Card Surg Annu 2007: 146150.

12.FF Ing , RG Grifka , MR Nihill , CE Mullins . Repeat dilatation of intravascular stents in congenital heart defects. Circulation 1995; 92: 893897.

13.N Carano , A Agnetti , B Tchana , A Squarcia , U Saquarcia . Descending thoracic aorta to left pulmonary fistula after stent implantation for acquired left pulmonary artery stenosis. J Interv Cardiol 2002; 15: 11413.

14.P Ewert , S Schubert , B Peters , H Abdul-Khaliq , N Nagdyman , PE Lange . The CP stent – short, long, covered – for the treatment of aortic coarctation, stenosis of pulmonary arteries and caval veins, and Fontan anastomosis in children and adults: an evaluation of 60 stents in 53 patients. Heart 2005; 91: 948953.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Cardiology in the Young
  • ISSN: 1047-9511
  • EISSN: 1467-1107
  • URL: /core/journals/cardiology-in-the-young
Please enter your name
Please enter a valid email address
Who would you like to send this to? *