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Phentolamine improves clinical outcome after balloon valvoplasty in neonates with severe pulmonary stenosis

  • Omar Galal (a1), Avedis Kalloghlian (a1), Babu M. Pittappilly (a1) and Nduna Dzimiri (a2)
Abstract

Two neonates with severe pulmonary stenosis deteriorated immediately after successful balloon valvoplasty as a result of increased infundibular obstruction. They were treated with β-adrenoceptor blockers and intravascular expansion with limited success. Phentolamine was then given, resulting in dramatic improvement. The children could be weaned from the ventilator within hours of starting this new therapeutic modality.

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Corresponding author
Moh. Omar Galal, MD, PH.D., Cardiovascular Department, MBC 16, King Faisal Specialist Hospital and RC, PO BOX 3354, Riyadh 11211, Saudi Arabia. Tel: 996-1-4647272; Fax: 009661-1-4427482
References
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1.Ben–Shachar, G, Cohen, MH, Sivakoff, Mc, Portman, MA, Riemenschneider, TA, Van Heeckeren, DW. Development of infundibular obstruction after percutaneous pulmonary balloon valvuloplasty. J Am Coll Cardiol 1985: 5; 754756.
2.Galal, O, Dzimiri, N, Moorji, A, Bakr, S, Almotrefi, AA. Sympathetic activity in children undergoing balloon vavuloplasty of pulmonary stenosis. Pediatr Res 1996; 39: 774778.
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Cardiology in the Young
  • ISSN: 1047-9511
  • EISSN: 1467-1107
  • URL: /core/journals/cardiology-in-the-young
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