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The Effect of Childhood Conduct Disorder and Cognitive Functioning on Adolescent Substance Use

Published online by Cambridge University Press:  07 November 2014

Seth C. Harty ,
Nicole K. Thorn ,
Jessica H. Kalmar ,
Jeffrey H. Newcorn  and
Jeffrey M. Halperin
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Abstract

Objective: To assess the impact of childhood conduct disorder (CD) and intelligence quotient (IQ) on later substance use in adolescence.

Methods: Neuropsychological and structured diagnostic evaluations were initially administered to 32 children with disruptive behavior disorder when they were 7–11 years of age. They were then re-evaluated on average 6.7 years later using an array of interviews and rating scales with a focus on substance use.

Results: Early CD and IQ scores together accounted for a significant proportion of the variance in later substance use (R2=.248). In addition, there was a significant CD and Verbal IQ interaction (R2=.164) such that high Verbal IQ was linked to increased substance use in adolescents who had childhood CD.

Conclusion: These data indicate that the presence of conduct disorder may interact with high Verbal IQ during childhood in such a way as to predict later adolescent substance use in disruptive behavior disorder populations.

Type
Original Research
Information
CNS Spectrums , Volume 9 , Issue 9 , September 2004 , pp. 661 - 666
Copyright
Copyright © Cambridge University Press 2004

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References

REFERENCES

1. Barkley, RA. Attention Deficit Hyperactivity Disorder: A Handbook for Diagnosis and Treatment. 2nd ed. New York, NY: The Guilford Press; 1998.Google Scholar
2. Fischer, M, Barkley, RA, Fletcher, KE, Smallish, L. The stability of dimensions of behavior in adhd and normal children over an 8 year followup. J Abnorm Child Psychol. 1993;21:315–337.CrossRefGoogle ScholarPubMed
3. Taylor, E, Chadwick, O, Heptinstall, E, Danckaerts, M. Hyperactivity and conduct problems as risk factors for adolescent development. J Am Acad Child Adolesc Psychiatry. 1996;35:1213–1226.CrossRefGoogle ScholarPubMed
4. Mannuzza, S, Klein, RG, Bessler, A, Malloy, P, Hynes, ME. Educational and Occupational outcome of hyperactive boys grown up. J Am Acad Child Adolesc Psychiatry. 1997;36:1222–127.CrossRefGoogle ScholarPubMed
5. Fischer, M, Barkley, RA, Edelbrock, CS, Smallish, L. The adolescent outcome of hyperactive children diagnosed by research criteria: II. Academic, attentional, and neuropsychological status. J Consult Clin Psychol. 1990;58:580–588.CrossRefGoogle ScholarPubMed
6. McGee, R, Partridge, F, Williams, S, Silva, PA. A twelve year follow-up of preschool hyperactive children. J Am Acad Child Adolesc Psychiatry. 1991;30:224–232.CrossRefGoogle ScholarPubMed
7. Mannuzza, S, Klein, R, Konig, PH, Giampino, TL. Hyperactive boys almost-grown up. IV. Criminality and its relationship to psychiatric status. Arch Gen Psychiatry. 1989;46:1073–1079.CrossRefGoogle ScholarPubMed
8. Lambert, NM, Hartsough, CS, Sassone, D, Sandoval, J. Persistence of hyperactivity symptoms from childhood to adolescence and associated outcomes. Am J Orthopsychiatry. 1987;57:22–32.CrossRefGoogle ScholarPubMed
9. Barkley, RA, Fischer, M, Edelbrock, CS, Smallish, L. The adolescent outcome of hyperactive children diagnosed by research criteria: I. An 8-year prospective follow-up study. J Am Acad Child Adolesc Psychiatry. 1990;29:546–557.CrossRefGoogle ScholarPubMed
10. MacDonald, VM, Achenbach, TM. Attention problems versus conduct problems as six-year predictors of problem scores in a national sample. J Am Acad Child Adolesc Psychiatry. 1996;35:1237–1246.CrossRefGoogle ScholarPubMed
11. Mannuzza, S, Klein, RG, Bonagura, N, Konig, PH, Shenker, R. Hyperactive boys almost grown up. II: Status of subjects without a mental disorder. Arch Gen Psychiatry. 1988;45:13–18.CrossRefGoogle ScholarPubMed
12. Boyle, MH, et al. Predicting substance use in early adolescence based on parent and teacher assessments of childhood psychiatric disorder: results from the Ontario Child Health Study follow-up. J Child Psychol Psychiatry. 1993;34:535–544.CrossRefGoogle ScholarPubMed
13. Biederman, J, Wilens, T, Mick, E, et al. Is ADHD a risk factor for psychoactive substance use disorders? Findings from a four-year prospective follow-up study. J Am Acad Child Adolesc Psychiatry. 1997;36:21–29.CrossRefGoogle ScholarPubMed
14. Flory, K, Milich, R, Lynman, DR, Leukefeld, C, Clayton, R. Relation between childhood disruptive behavior disorders and substance use and dependence symptoms in young adulthood: individuals with symptoms of attention-deficit/hyperactivity disorder and conduct disorder are uniquely at risk. Psychol Addict Behav. 2003;17:151–158.CrossRefGoogle ScholarPubMed
15. Molina, BSG, Pelham, WE Jr.Childhood predictors of adolescent substance use in a longitudinal study of children with ADHD. J Abnorm Psychol. 2003;112:497–507.CrossRefGoogle Scholar
16. Mannuzza, S, Klein, RG, Bonagura, N, Malloy, P, Giampino, TL, Addalli, KA. Hyperactive boys almost grown up. V: Replication of psychiatric status. Arch Gen Psychiatry. 1991;48:77–83.CrossRefGoogle ScholarPubMed
17. Schubiner, H, Tzelepis, A, Milberger, S, et al. Prevelance of attention-deficit/hyperactivity disorder and conduct disorder among substance abusers. J Clin Psychiatry. 2000;61:244–251.CrossRefGoogle Scholar
18. Boyle, MH, Offord, DR, Racine, YA, Szatmari, P, Fleming, JE, Links, PS. Predicting substance use in late adolescence: results from the Ontario Child Health Study follow-up. Am J Psychiatry. 1992;149:761–767.Google ScholarPubMed
19. Crowley, TJ, Mikulich, SK, MacDonald, M, Young, SE, Zerbe, GO. Substance-dependent, conduct-disordered adolescent males: severity of diagnosis predicts 2-year outcome. Drug Alcohol Depend. 1998;49:225–237.CrossRefGoogle ScholarPubMed
20. Windle, M. A longitudinal study of antisocial behaviors in early adolescence as predictors of late adolescent substance use: gender and ethnic group differences. J Abnorm Psychol. 1990;99:86–91.CrossRefGoogle ScholarPubMed
21. Elkins, IJ, Iacono, WG, Doyle, AE, McGue, M. Characteristics associated with the persistence of antisocial behavior: results from recent longitudinal research. Aggress Violent Behav. 1997;2:101–124.CrossRefGoogle Scholar
22. Hinshaw, SP. Externalizing behavior problems and academic underachievement in childhood and adolescence: causal relationships and underlying mechanisms. Psychol Bull. 1992;111:127–155.CrossRefGoogle ScholarPubMed
23. Lynam, D, Moffitt, T, Stouthamer-Loeber, M. Explaining the relation between IQ and delinquency: class, race, test motivation, school failure, or self-control? J Abnorm Psychol. 1993;102:187–196.CrossRefGoogle ScholarPubMed
24. Bassarath, L. Conduct disorder: a biopsychosocial review. Can J Psychiatry. 2001;46:609–616.CrossRefGoogle ScholarPubMed
25. Flemming, JP, Kellam, SG, Brown, CH. Early predictors of age at first use of alcohol, marijuana, and cigarettes. Drug Alcohol Depend. 1982;9:285–303.CrossRefGoogle Scholar
26. Grant, BF, Dawson, DA. Age of onset of drug use and its association with DSM-IV drug abuse and dependence: results from the National Longitudinal Alcohol Epidemiologic Survey. J Subst Abuse. 1998;10:163–173.CrossRefGoogle ScholarPubMed
27. Span, SA, Earleywine, M. Cognitive functioning moderates the relation between hyperactivity and drinking habits. Alcohol Clin Exp Res. 1999;23:224–229.CrossRefGoogle ScholarPubMed
28. Block, RI, Erwin, WJ, Ghoneim, MM. Chronic drug use and cognitive impairments. Pharmacol Biochem Behav. 2002;73:491–504.CrossRefGoogle ScholarPubMed
29. Halperin, JM, Sharma, V, Siever, LJ, et al. Serotonergic function in aggressive and nonaggressive boys with attention deficit hyperactivity disorder. Am J Psychiatry. 1994;151:243–248.Google ScholarPubMed
30. Diagnostic and Statistical Manual of Mental Disorders. 3rd ed. rev. Washington, DC: American Psychiatric Association; 1987.Google Scholar
31. Ivanov, I, Schulz, K, Kalmar, J, Newcorn, J, Halperin, J. Stimulant treatment for childhood and adolescent substance use outcome. Poster presented at: the annual meeting of the American Academy of Child and Adolescent Psychiatry; October 14–19, 2003: Miami, FL.Google Scholar
32. Rourke, BP. Socioemotional disturbances of learning disabled children. J Consult Clin Psychol. 1988;56:801–810.CrossRefGoogle ScholarPubMed