Skip to main content
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 7
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Beasley, David WC 2011. Vaccines and immunotherapeutics for the prevention and treatment of infections with West Nile virus. Immunotherapy, Vol. 3, Issue. 2, p. 269.

    Brault, Aaron C. Langevin, Stanley A. Bowen, Richard A. Panella, Nicholas A. Biggerstaff, Brad J. Miller, Barry R. and Komar, Nicholas 2004. Differential Virulence of West Nile Strains for American Crows. Emerging Infectious Diseases, Vol. 10, Issue. 12, p. 2161.

    Kuno, Goro 2003. Advances in Virus Research Volume 61.

    Takasaki, Tomohiko Yabe, Sadao Nerome, Reiko Ito, Mikako Yamada, Ken-Ichiro and Kurane, Ichiro 2003. Partial protective effect of inactivated Japanese encephalitis vaccine on lethal West Nile virus infection in mice. Vaccine, Vol. 21, Issue. 31, p. 4514.

    Beasley, David W.C. Li, Li Suderman, Miguel T. and Barrett, Alan D.T. 2002. Mouse Neuroinvasive Phenotype of West Nile Virus Strains Varies Depending upon Virus Genotype. Virology, Vol. 296, Issue. 1, p. 17.

    Burt, Felicity J. Grobbelaar, Antoinette A. Leman, Patricia A. Anthony, Fiona S. Gibson, Georgina V.F. and Swanepoel, Robert 2002. Phylogenetic Relationships of Southern African West Nile Virus Isolates. Emerging Infectious Diseases, Vol. 8, Issue. 8, p. 820.

    Morvan, J. Besselaar, T. Fontenille, D. and Coulanges, P. 1990. Antigenic variations in West Nile virus strains isolated in Madagascar since 1978. Research in Virology, Vol. 141, Issue. 6, p. 667.


Antigenic relationship of West Nile strains by titre ratios calculated from cross-neutralization test results

  • N. K. Blackburn (a1), D. L. Thompson (a1) and P. G. Jupp (a1)
  • DOI:
  • Published online: 19 October 2009

The antigenic relationship of ten South African West Nile isolates, the South African prototype virus H442, the Egyptian strain EG101 and the Indian strain G2266 were compared using titre ratios. The titre ratios or ‘R’ values were calculated from heterologous and homologous neutralization titres and expressed as a percentage.

Substantial antigenic differences were demonstrated between the South African prototype strain and the majority of the recently obtained South African isolates, seven of which were fairly closely related and possibly form a distinct antigenic sub-set. The recent isolates also differed from the Egyptian and Indian West Nile isolates. The heterologous results between the South African West Nile strains and the Indian strain G2266 suggest that prior infection with an Indian West Nile virus would give poor protection against the South African viruses, whereas the reverse would not be so.

Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

M. A. Odelala & A. Fabiyi (1976). Antigenic relationships among Nigerian strains of West Nile virus by complement fixation and agar gel precipitation techniques. Transactions of the Royal Society of Tropical Medicine and Hygiene 70, 138140.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *