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Clam-associated vibriosis, USA, 1988–2010

  • R. B. SLAYTON (a1) (a2), A. E. NEWTON (a2), A. DEPAOLA (a3), J. L. JONES (a3) and B. E. MAHON (a2)...

Infections with Vibrio spp. have frequently been associated with consumption of bivalve molluscs, especially oysters, but illness associated with clams has also been well documented. We describe the 2312 domestically acquired foodborne Vibrio infections reported to the Cholera and Other Vibrio Illness Surveillance system from 1988 to 2010. Clams were associated with at least 4% (93 persons, ‘only clams’) and possibly as many as 24% (556 persons, ‘any clams’) of foodborne cases. Of those who consumed ‘only clams’, 77% of infections were caused by V. parahaemolyticus. Clam-associated illnesses were generally similar to those associated with other seafood consumption. Clams associated with these illnesses were most frequently harvested from the Atlantic coastal states and eaten raw. Our study describes the contribution of clams to the overall burden of foodborne vibriosis and indicates that a comprehensive programme to prevent foodborne vibriosis need to address the risks associated with clams.

Corresponding author
* Author for correspondence: Dr R. B. Slayton, U.S. Centers for Disease Control and Prevention, 1600 Clifton Road, MS A-31, Atlanta, GA 303 33 USA. (Email:
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1. Cazorla C, et al. Fatal Vibrio vulnificus infection associated with eating raw oysters, New Caledonia. Emerging Infectious Diseases 2011; 17: 136137.
2. Chen Y, et al. Foodborne pathogens in retail oysters in south China. Biomedical and Environmental Sciences 2010; 23: 3236.
3. Depaola A, et al. Survey of postharvest-processed oysters in the United States for levels of Vibrio vulnificus and Vibrio parahaemolyticus. Journal of Food Protection 2009; 72: 21102113.
4. Han F, et al. Characterization of clinical and environmental types of Vibrio vulnificus isolates from Louisiana oysters. Foodborne Pathogens and Disease 2009; 6: 12511258.
5. Haq SM, Dayal HH. Chronic liver disease and consumption of raw oysters: a potentially lethal combination – a review of Vibrio vulnificus septicemia. American Journal of Gastroenterology 2005; 100: 11951199.
6. Kirs M, et al. A survey of oysters (Crassostrea gigas) in New Zealand for Vibrio parahaemolyticus and Vibrio vulnificus. International Journal of Food Microbiology 2011; 147: 149153.
7. Vieira RH, et al. Raw oysters can be a risk for infections. Brazilian Journal of Infectious Diseases 2010; 14: 6670.
8. Weis KE, et al. Vibrio illness in Florida, 1998–2007. Epidemiology and Infection 2011; 139: 591598.
9. Dunn J, Fullerton K. Update to vibriosis case definition: Council of State and Territorial Epidemiologists (CSTE). 11-ID-12 Committee, 2011.
10. CDC. Foodborne Disease Outbreak Surveillance System (FDOSS).
11. U.S. Food & Drug Administration. National Shellfish Sanitation Program Guide for the Control of Molluscan Shellfish – 2007 Revision. Department of Health and Human Services, 2007.
12. U.S. Food & Drug Administration. National Shellfish Sanitation Program Guide for the Control of Molluscan Shellfish – 2009 Revision. Department of Health and Human Services, 2009.
13. DePaola A, et al. Bacterial and viral pathogens in live oysters: 2007 United States market survey. Applied and Environmental Microbiology 2010; 76: 27542768.
14. National Oceanic and Atmospheric Administration (NOAA). FishWatch U.S. Seafood Facts ( Accessed 19 June 2013.
15. Gooch JA, et al. Growth and survival of Vibrio parahaemolyticus in postharvest American oysters. Journal of Food Protection 2002; 65: 970974.
16. DePaola A, et al. Analysis of Vibrio vulnificus from market oysters and septicemia cases for virulence markers. Applied and Environmental Microbiology 2003; 69: 40064011.
17. Interstate Shellfish Sanitation Conference (ISSC), Vibrio Management Committee. Vibrio vulnificus controls: Proposal No. 11-201 ( Accessed 22 July 2013.
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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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