Hostname: page-component-8448b6f56d-dnltx Total loading time: 0 Render date: 2024-04-23T17:25:14.881Z Has data issue: false hasContentIssue false
  • English
  • Français

Differentiation between serological responses to Brucella suis and Yersinia enterocolitica serotype O[ratio ]9 after natural or experimental infection in pigs

Published online by Cambridge University Press:  07 September 2005

G. JUNGERSEN ,
V. SØRENSEN ,
S. B. GIESE ,
J. A. STACK  and
U. RIBER
G. JUNGERSEN
Affiliation:
Department of Veterinary Diagnostics and Research, Danish Institute of Food and Veterinary Research, Copenhagen, Denmark
V. SØRENSEN
Affiliation:
Department of Veterinary Diagnostics and Research, Danish Institute of Food and Veterinary Research, Copenhagen, Denmark
S. B. GIESE
Affiliation:
Department of Veterinary Diagnostics and Research, Danish Institute of Food and Veterinary Research, Copenhagen, Denmark
J. A. STACK
Affiliation:
Department of Bacterial Diseases, Veterinary Laboratories Agency, Addlestone, Surrey, UK
U. RIBER
Affiliation:
Department of Veterinary Diagnostics and Research, Danish Institute of Food and Veterinary Research, Copenhagen, Denmark
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

False-positive serological reactions (FPSR) due to infections with Yersinia enterocolitica serotype O[ratio ]9 (YeO[ratio ]9) are a problem in tests for brucellosis. In the present study, FPSR in classical and novel tests for brucellosis following experimental infections of pigs with YeO[ratio ]9 were compared with responses of B. suis biovar 2-inoculated pigs. FPSR were limited to 2–9 weeks post-YeO[ratio ]9 inoculation, while B. suis-infected pigs were test-positive throughout the 21-week period of investigation. Although YeO[ratio ]9-inoculated pigs exhibited FPSR in Brucella tests for a limited period of time, the serological responses in a YeO[ratio ]9-purified O-antigen indirect ELISA did not decrease accordingly. Analysis of available cross-sectional serum samples from pig herds naturally infected with YeO[ratio ]9 or B. suis biovar 2 confirmed that the observed difference in the duration of the serological responses between the two infections could be used to discriminate between herds infected with B. suis biovar 2 and YeO[ratio ]9.

Type
Research Article
Information
Epidemiology & Infection , Volume 134 , Issue 2 , April 2006 , pp. 347 - 357
Copyright
2005 Cambridge University Press