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A three-year diagnostic and epidemiological study on viral infantile diarrhoea in Rome

Published online by Cambridge University Press:  19 October 2009

G. Donelli ,
F. M. Ruggeri ,
A. Tinari ,
M. L. Marziano ,
D. Menichella ,
D. Caione ,
C. Concato ,
G. Rocchi  and
S. Vella
G. Donelli
Affiliation:
Laboratorio di Ultrastrutture, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome
F. M. Ruggeri
Affiliation:
Laboratorio di Ultrastrutture, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome
A. Tinari
Affiliation:
Laboratorio di Ultrastrutture, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome
M. L. Marziano
Affiliation:
Laboratorio di Ultrastrutture, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome
D. Menichella
Affiliation:
Ospedale del Bambino Gesù, Piazza S. Onofrio 4, 00165 Rome
D. Caione
Affiliation:
Ospedale del Bambino Gesù, Piazza S. Onofrio 4, 00165 Rome
C. Concato
Affiliation:
Ospedale del Bambino Gesù, Piazza S. Onofrio 4, 00165 Rome
G. Rocchi
Affiliation:
Clinica Medica III, Università ‘La Sapienza’, Viale Regina Elena, 00161 Rome, Italy
S. Vella
Affiliation:
Clinica Medica III, Università ‘La Sapienza’, Viale Regina Elena, 00161 Rome, Italy
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Rotavirus infection was demonstrated in 168 (29·3%) of 573 children hospitalized for acute diarrhoea in Rome between January 1982 and December 1984. Laboratory diagnosis of these infections was made by transmission electron microscopy and enzyme immunoassay techniques with an overall agreement of 91·3%. Astroviruses, adenoviruses and small round viruses were detected in the faeces of 36 patients (6·4%). Whereas in 1982 rotavirus positive patients were clustered in the winter and following spring, in the following years cases were recorded all year round. The median age of patients with rotavirus infections was 17, 10 and 11·5 months in 1982, 1983 and 1984, respectively. In addition, a smaller number of rotavirus positive cases were admitted in 1983 when compared to those admitted during the previous as well as the subsequent years. It is suggested that a herd immunity was induced in the population by epidemic spread of rotavirus in the first half of 1982.

Type
Research Article
Information
Epidemiology & Infection , Volume 100 , Issue 2 , April 1988 , pp. 311 - 320
Copyright
Copyright © Cambridge University Press 1988

References

REFERENCES

Albert, M. J. (1986). Enteric adenovirus. Archives of Virology 88, 1–17.Google Scholar
Brandt, C. D., Kim, H. W., Rodriguez, W. J., Arrobio, J. O., Jeffries, B. C. & Parrott, R. H. (1982). Rotavirus gastroenteritis and weather. Journal of Clinical Microbiology 16, 478–482.Google Scholar
Brandt, C. D., Kim, H. W., Rodriguez, W. J., Arrobio, J. O., Jeffries, B. C.Stallings, E. P., Lewis, C., Miles, A. J., Chanock, R. M., Kapikian, A. Z. & Parrott, R. H. (1983). Pediatric viral gastroenteritis during eight years of study. Journal of Clinical Microbiology 18, 71–78.Google Scholar
Brandt, C. D., Kim, H. W., Yolken, R. H., Kapikian, A. Z., Arrobio, J. O., Rodriguez, W. J., Wyatt, R. G., Chanock, R. M. & Parrott, R. H. (1979). Comparative epidemiology of two rotavirus serotypes and other viral agents associated with pediatric gastroenteritis. American Journal of Epidemiology 110, 243–254.Google Scholar
Bryden, A. S., Davies, H. A., Hadley, R. E., Flewett, T. H., Morris, C. A. & Oliver, P. (1975). Rotavirus enteritis in the West Midlands during 1974. Lancet ii, 241–243.Google Scholar
Caul, E. O., Paver, W. K. & Clarke, S. K. R. (1975). Coronavirus particles in faeces from patients with gastroenteritis. Lancet i, 1192.CrossRefGoogle Scholar
Cukor, G. & Blacklow, N. R. (1984). Human viral gastroenteritis. Microbiological Reviews 48, 157–179.Google Scholar
Flewett, T. H., Bryden, A. S. & Davies, H. (1974). Diagnostic electron microscopy of faeces. I. The viral flora of the faeces as seen by electron microscopy. Journal of Clinical Pathology 27, 603–614.Google Scholar
Hammond, G. W., Ahluwalia, G. S., Barker, F. G., Horsman, G. & Hazelton, P. R. (1982). Comparison of direct and indirect enzyme immunoassays with direct ultracentrifugation before electron microscopy for detection of rotaviruses. Journal of Clinical Microbiology 16, 53–59.Google Scholar
Herring, A. J., Inglis, N. F., Ojeh, C. K., Snodgrass, D. R. & Menzies, J. D. (1982). Rapid diagnosis of rotavirus infection by direct detection of viral nucleic acid in silver-stained polyacrylamidc gels. Journal of Clinical Microbiology 16, 473–477.Google Scholar
Kapikian, A. Z., Greenberg, H. B., Wyatt, R. G., Kalica, A. R. & Chanock, R. M. (1982). The Norwalk group of viruses. Agents associated with epidemic viral gastroenteritis. In Virus Infections of the Gastrointestinal Tract (ed. Tyrrell, D. A. J. & Kapikian, A. Z.), pp. 147–177. New York Basel: Marcel Dekkcr, Inc.Google Scholar
Kapikian, A. Z., Kim, H. W., Wyatt, R. G., Cline, W. L., Arrobio, J. O., Brandt, C. D., Rodriguez, W. J., Sack, D. A., Chanock, R. M. & Parrott, R. H. (1970). Human rcoviruslike agent as tho major pathogen associated with ‘winter’ gastroenteritis in hospitalized infants and young children. New England Journal of Medicine 294, 965–972.CrossRefGoogle Scholar
Konno, T., Suzuki, H., Tmai, A., Kutsuzawa, T., Ishida, N., Katsushima, N., Sakamoto, M., Kitaoka, S., Tsuboi, R. & Adachi, M. (1978). A long-term survey of rotavirus infection in Japanese children with acute gastroenteritis. Journal of Infectious Diseases 138, 569–570.Google Scholar
Konno, T., Suzuki, H., Katsushima, N., Imai, A., Tazawa, F., Kutsuzawa, T., Kitaoka, S., Sakamoto, M., Yazaki, N. & Ishida, N. (1983). Influence of temperature and relative humidity on human rotavirus infection in Japan. Journal of Infectious Diseases 147, 125–128.CrossRefGoogle ScholarPubMed
Laemmli, U. K. (1970). Cleavage of structural proteins during tho assembly of tho head of bacteriophago T4. Nature 227, 680–685.CrossRefGoogle Scholar
Madeley, C. R. & Cosgrove, B. P. (1975). 28 nm particles in faeces in infantile gastroenteritis. Lancet ii, 451–452.Google Scholar
Madeley, C. R. & Cosgrove, B. P. (1976). Caliciviruses in man. lancet i, 199–200.Google Scholar
Madeley, C. R., Cosgrove, B. P., Bell, E. J. & Fallon, R. J. (1977). Stool viruses in babies in Glasgow. 1. Hospital admissions with diarrhoea. Journal of Hygiene 78, 261–273.CrossRefGoogle Scholar
Middleton, P. J., Szymanski, M. T. & Petric, M. (1977). Viruses associated with acute gastroenteritis in young children. American Journal of Diseases of Children 131, 733–737.Google Scholar
Miotti, P. G., Eiden, J. & Yolken, R. H. (1985). Comparative efficiency of commercial immunoassays for tho diagnosis of rotavirus gastroenteritis during tho course of infection. Journal of Clinical Microbiology 22, 693–698.Google Scholar
Monto, A. S. & Koopman, J. S. (1980). The Tecumsch study. XI. Occurrence of acute enteric illness in the community. American Journal of Epidemiology 112, 323–333.Google Scholar
Riepenhoff-Talty, M., Saif, L. J., Barrett, H. J., Suzuki, H. & Ogra, P. L. (1983). Potential spectrum of etiological agents of viral enteritis in hospitalized infants. Journal of Clinical Microbiology 17, 352–356.CrossRefGoogle ScholarPubMed
Snyder, J. D. & Merson, M. H. (1982). The magnitude of the global problem of acute diarrhoeal disease: a review of active surveillance data. Bulletin of the World Health Organisation 60, 605–613.Google ScholarPubMed
Steering Committee of the Scientific Working Group on Viral Diarrhoeas, Who Programme for Diarrhoeal Diseases Control (1984). Nomenclature of human rotaviruses: designation of subgroups and serotypes. Bulletin of the World Health Organization 62, 501–503.Google Scholar
Tufvesson, B. & Johnsson, T. (1976). Occurrence of reo-like viruses in young children with acute gastroenteritis. Ada Pathologica Microbiologica Scandinavica. Sect. B 84, 22–28.Google Scholar
Uhnoo, I., Wadell, G., Svensson, L. & Johansson, M. E. (1984). Importance of enteric adenoviruses 40 and 41 in acute gastroenteritis in infants and young children. Journal of Clinical Microbiology 20, 365–372.CrossRefGoogle ScholarPubMed
Who Scientific Working Group (1980). Rotavirus and other viral diarrhoeas. Bulletin of the World Health Organization 58, 183–198.Google Scholar