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Relative abundance of enterovirus serotypes in sewage differs from that in patients: clinical and epidemiological implications

Published online by Cambridge University Press:  15 May 2009

T. Hovi ,
M. Stenvik  and
M. Rosenlew
T. Hovi
Affiliation:
Enterovirus Laboratory, National Public Health Institute (KTL), Mannerheimintie 166, FIN-00300 Helsinki, Finland
M. Stenvik
Affiliation:
Enterovirus Laboratory, National Public Health Institute (KTL), Mannerheimintie 166, FIN-00300 Helsinki, Finland
M. Rosenlew
Affiliation:
Enterovirus Laboratory, National Public Health Institute (KTL), Mannerheimintie 166, FIN-00300 Helsinki, Finland
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Summary

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One thousand one hundred and sixty-one non-polio enterovirus strains, isolated during regular screening of Finnish sewage specimens, were analysed for serotype distribution seasonally through 20 years, and the findings were compared with similar data based on 1681 clinical isolates. Coxsackievirus B4 (CBV-4), CBV-5, echovirus 11 (EV-11), EV-6, CBV-2 and CBV-3 were the most common serotypes in sewage, whilst CBV-5, EV-11, coxsackievirus A9, EV-22, CBV-3 and EV-30 were the most common clinical isolates. Reasons for the differences are not known but several explanations are possible. Seasonal variation of enterovirus occurrence in both sources showed an expected peak in the autumn with a trough in the spring. The occurrence of enteroviruses was closely correlated with monthly recordings of mean relative humidity. A further observation concerning the clinical specimens in Finland was the relative excess of some serotypes, such as echovirus 22 and coxsackievirus A9, and paucity of others, for instance, echoviruses 4 and 9, when compared to published data from other countries. This is consistent with the idea of geographically restricted circulation of enteroviruses.

Type
Research Article
Information
Epidemiology & Infection , Volume 116 , Issue 1 , February 1996 , pp. 91 - 97
Copyright
Copyright © Cambridge University Press 1996

References

1.Cherry, JD. Enteroviruses: Polioviruses (poliomyelitis), coxsackieviruses, echoviruses, and enteroviruses. In: Feigin, RD, Cherry, JD, eds. Textbook of pediatric infections, 2nd ed.Philadelphia: Saunders, 1987: 1729–90.Google Scholar
2.Melnick, JL. Enteroviruses: Polioviruses, coxsackie-viruses, echoviruses and newer enteroviruses. In: Fields, BN, Knipe, DM, Chanoch, RM, eds. Fields virology 2nd ed. vol 1. New York: Raven Press, 1990: 549–605.Google Scholar
3.Strikas, RA, Andersson, LJ, Parker, RA. Temporal and geographic patterns of isolates of nonpolio enterovirus in the United States, 1970–1983. J Infect Dis 1986; 159: 346–51.CrossRefGoogle Scholar
4.Kogon, A, Spigland, I, Frothingham, TC et al. , The virus watch program: A continuous surveillance of viral infections in metropolitan New York families. VII. Observations on viral excretion, intrafamilial spread and illness association in coxsackievirus and echovirus infections. Am J Epidemiol 1969; 89: 51–61.CrossRefGoogle Scholar
5.Berg, G, Bodily, H, Lennette, EH, Melnick, JL, Metcalf, TG, eds. Viruses in water. Washington DC: American Public Health Association, 1976.Google Scholar
6.Rao, VC, Metcalf, TG, Melnick, JL. Human viruses in sediments, sludges, and soils. Bull WHO 1986; 64: 1–14.Google ScholarPubMed
7.Lapinleimu, K, Stenvik, M. Experiences with polio vaccination and herd immunity in Finland. Dev Biol Standard 1981; 47: 241–6.Google ScholarPubMed
8.Lapinleimu, K, Stenvik, M, Soininen, L. Virus isolations from sewage in Finland. In: Fortuine, R. Proceedings of the Sixth International Symposium on Circumpolar Health (Anchorage, Alaska, 1984). Seattle: University of Washington Press, 1985: 213–6.Google Scholar
9.Pöyry, T, Stenvik, M, Hovi, T. Viruses in sewage waters during and after a poliomyelitis outbreak and subsequent nationwide oral poliovirus vaccine campaign in Finland. Appl Environ Microbiol 1988; 54: 371–4.CrossRefGoogle ScholarPubMed
10.Hovi, T, Cantell, K, Huovilainen, A et al. , Outbreak of paralytic poliomyelitis in Finland: widespread circulation of antigenically altered poliovirus type 3 in a vaccinated population. Lancet 1986; 1: 1427–32.CrossRefGoogle Scholar
11.Heino, R, Hellsten, E. Climatological statistics in Finland 1961–1980. Meteorol Yearbook of Finland 1980: 80, Part 1 a.Google Scholar
12.Rico-Hesse, R, Pallansch, MA, Nottay, BK, Kew, OM. Geographic distribution of poliovirus type 1 genotypes. Virology 1987; 160: 311–22.CrossRefGoogle ScholarPubMed
13.Hyöty, H, Hiltunen, M, Knip, M et al. , A prospective study on the role of coxsackie B and other enterovirus infections in the pathogenesis of insulin-dependent diabetes mellitus. Diabetes 1995; 44: 652–7.CrossRefGoogle Scholar
14.Grist, NR, Bell, EJ, Assaad, F. Enteroviruses in human disease. Progr Med Virol 1978; 24: 114–57.Google ScholarPubMed
15.Hovi, T, Stenvik, M. Selective isolation of poliovirus in recombinant murine cell line expressing the human poliovirus receptor gene. J Clin Microbiol 1994; 32: 1366–8.CrossRefGoogle ScholarPubMed
16.Hemmes, JH, Winkler, KC, Kool, SM. Virus survival as a seasonal factor in influenza and poliomyelitis. Nature 1960; 188: 431–1.CrossRefGoogle Scholar
17.Ijaz, MK, Sattar, SA, Johnson-Lussenburg, CM, Springthorpe, VS. Comparison of the airborne survival of calf rotavirus and poliovirus type 1 (Sabin) aerosolized as a mixture. Appl Environ Microbiol 1985; 49: 289–93.CrossRefGoogle ScholarPubMed
18.Martins, MT, Scares, LA, Marques, E, Molina, AG. Human enteric viruses isolated from influents of sewage treatment plants in S. Paulo, Brazil. Water Sci Technol 1983; 15: 69–73.CrossRefGoogle Scholar