Skip to main content
×
Home
    • Aa
    • Aa

Serological evidence for the reservoir hosts of cowpox virus in British wildlife

  • A. C. Crouch (a1) (a2) (a3), D. Baxby (a1), C. M. McCracken (a2) (a3), R. M. Gaskell (a2) and M. Bennett (a3)...
Abstract
Summary

The reservoir host of cowpox virus in Western Europe is not known, but epidemiological evidence from human and feline infections indicates that the virus is probably endemic in small wild rodents. Therefore, serum and tissue samples were collected from a variety of wild British mammals and some birds, and tested for evidence of Orthopoxvirus infection. Antibody reacting with cowpox virus was detected in 9/44 (20%) bank voles (Clethrionomys glareolus), 8/24 (33%) field voles (Microtus agrestis), 17/86 (20%) wood mice (Apodemus sylvaticus) and 1/44 house mice (Mus musculus), but in no other animal species tested. Although virus was not isolated from any animal, this serological survey, together with other evidence, suggests that bank and field voles and wood mice are the main reservoir hosts of cowpox virus in Great Britain.

Copyright
Corresponding author
* Author for correspondence.
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

3.D Baxby , M Bennett , B Getty . Human cowpox; a review based on 54 cases, 1969–93. Br J Dermatol 1994; 131: 598607.

6.M Bennett , CJ Gaskell , RM Gaskell , D Baxby , TJ Gruffydd-Jones . Poxvirus infection in the domestic cat. Some clinical and epidemiological observations. Vet Rec 1986; 118: 387–90.

8.D Baxby . Is cowpox misnamed ? - a review of 10 human cases. B M J 1977; 1: 1379–81.

10.N Nowotny . The domestic cat: a possible transmitter of viruses from rodents to man. Lancet 1994; 343: 921.

14.JL Burton . Of mice and milkmaids, cats and cowpox. Lancet 1994; 343: 67.

16.D Boulanger , B Brochier , A Crouch , Comparison of the susceptibility of the red fox (Vulpes vulpes) to a vaccinia-rabies recombinant virus and to cowpox virus. Vaccine 1995; 13: 215–9.

17.C Kaplan . Vaccinia virus: a suitable vehicle for recombinant vaccines? Arch Virol 1989; 106: 127–39.

19.RM Gaskell , CJ Gaskell , RJ Evans , Natural and experimental pox virus infection in the domestic cat. Vet Rec 1983; 112: 164–70.

20.J Naidoo , D Baxby , M Bennett , RM Gaskell , CJ Gaskell . Characterisation of ortho-poxviruses isolated from feline infections in Britain. Arch Virol 1992; 125: 261–72.

25.D Baxby . Poxvirus hosts and reservoirs. Arch Virol 1977; 55: 169–79.

27.RML Buller , M Potter , GD Wallace . Variable resistance to ectromelia (mousepox) virus among general of Mus. In: M Potter , ed. The wild mouse in immunology. New York: Springer1986; 319–22.

28.CA McGaughey , R Whitehead . Outbreaks of infectious ectromelia in laboratory and wild mice. J Path Bact 1933; 37: 253–6.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×